Examining the Impact of Trauma-Induced Immune Depression on the Development of Nosocomial Infections

2.50
Hdl Handle:
http://hdl.handle.net/10755/148944
Type:
Presentation
Title:
Examining the Impact of Trauma-Induced Immune Depression on the Development of Nosocomial Infections
Abstract:
Examining the Impact of Trauma-Induced Immune Depression on the Development of Nosocomial Infections
Conference Sponsor:Sigma Theta Tau International
Conference Year:2005
Author:Fox-Wasylyshyn, Susan M., RN, MScN
P.I. Institution Name:University of Windsor
Title:Mrs.
Co-Authors:Maher M. El-Masri, RN, PhD; Margaret MAE Oldfield, BScN, BA, RN
Background: Early identification of the risk factors associated with the development of nosocomial infections (NI) is key to the prevention and control of these infections in critically ill trauma patients. To date, little attention has been paid to the impact of trauma-induced humoral and cell-mediated immune depression on the risk of developing NI. Purpose: The purposes of this study are to: (1) examine the effect of immune depression on the risk of developing NI among critically ill patients, and (2) examine whether immune depression differs between trauma and non-trauma patients. Research Questions: 1) After adjusting for other known risk factors, what is the effect of immune depression on the risk of developing NI among critically ill patients? 2) Are the risk factors for developing NI different between trauma and non-trauma patients? Methods: A prospective non-experimental cohort design was conducted on 212 critical care patients in the intensive care unit of a community hospital. Patients were followed until they: (a) developed NI or, (b) were discharged from the intensive care unit without infection. Data Analysis: Data analysis procedures are in progress and they include basic descriptive statistics, univariate analysis (chi square and t-tests). Hierarchical multivariate logistic regression analyses will be used to examine the research questions. Implications: The findings of this study are expected to facilitate new directions for the early recognition of ?high-risk? individuals which may lead to decreased hospital length of stay, decreased costs, improved health outcomes, and decreased mortality. Further, this study will provide information that can be used by critical care practitioners to develop clinical standards for the prevention and control of risk factors associated with NI.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleExamining the Impact of Trauma-Induced Immune Depression on the Development of Nosocomial Infectionsen_GB
dc.identifier.urihttp://hdl.handle.net/10755/148944-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Examining the Impact of Trauma-Induced Immune Depression on the Development of Nosocomial Infections</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2005</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Fox-Wasylyshyn, Susan M., RN, MScN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of Windsor</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Mrs.</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">sfox@uwindsor.ca</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Maher M. El-Masri, RN, PhD; Margaret MAE Oldfield, BScN, BA, RN</td></tr><tr><td colspan="2" class="item-abstract">Background: Early identification of the risk factors associated with the development of nosocomial infections (NI) is key to the prevention and control of these infections in critically ill trauma patients. To date, little attention has been paid to the impact of trauma-induced humoral and cell-mediated immune depression on the risk of developing NI. Purpose: The purposes of this study are to: (1) examine the effect of immune depression on the risk of developing NI among critically ill patients, and (2) examine whether immune depression differs between trauma and non-trauma patients. Research Questions: 1) After adjusting for other known risk factors, what is the effect of immune depression on the risk of developing NI among critically ill patients? 2) Are the risk factors for developing NI different between trauma and non-trauma patients? Methods: A prospective non-experimental cohort design was conducted on 212 critical care patients in the intensive care unit of a community hospital. Patients were followed until they: (a) developed NI or, (b) were discharged from the intensive care unit without infection. Data Analysis: Data analysis procedures are in progress and they include basic descriptive statistics, univariate analysis (chi square and t-tests). Hierarchical multivariate logistic regression analyses will be used to examine the research questions. Implications: The findings of this study are expected to facilitate new directions for the early recognition of ?high-risk? individuals which may lead to decreased hospital length of stay, decreased costs, improved health outcomes, and decreased mortality. Further, this study will provide information that can be used by critical care practitioners to develop clinical standards for the prevention and control of risk factors associated with NI.</td></tr></table>en_GB
dc.date.available2011-10-26T09:53:20Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T09:53:20Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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