Sleep Disturbances and Quality of Life in Patients with Advanced Lung and Colorectal Cancer

2.50
Hdl Handle:
http://hdl.handle.net/10755/149138
Type:
Presentation
Title:
Sleep Disturbances and Quality of Life in Patients with Advanced Lung and Colorectal Cancer
Abstract:
Sleep Disturbances and Quality of Life in Patients with Advanced Lung and Colorectal Cancer
Conference Sponsor:Sigma Theta Tau International
Conference Year:2003
Author:Vena, Catherine I., RN, MSN
P.I. Institution Name:Emory University
Title:Doctoral Candidate
Co-Authors:Kathy P. Parker, PhD, RN, FAAN; Rebecca Allen, PhD; Donald L. Bliwise, PhD; Sanjay R. Jain, MD, PhD; Laura P. Kimble, PhD, RN
OBJECTIVE: Since few studies have specifically focused on the impact of sleep quantity and quality on the quality of life (QOL) of advanced cancer patients, we are examining these variables in a cohort of patients with late-stage malignancy. DESIGN: Descriptive, correlational. SAMPLE: Fourteen stage IV colorectal (n = 7) or lung cancer (n = 7) outpatients (mean ± SD age 52.6±12.68, range 28-69) who were cognitively intact, had no history of a sleep, neurologic, mood, anxiety or psychotic disorder, or known cerebral metastases. METHODS: Sleep variables (total sleep time – TST, subjective sleep quality) were measured by the Pittsburgh Sleep Quality Index (PSQI; score of >=5 indicates sleep disturbance). QOL variables, measured by the Medical Outcomes Study Short Form 36, version 2 (SF36v2), included two summary and eight domain scores (population norm 50): physical composite, mental composite, physical function, role physical, bodily pain, general health, vitality, social function, role emotional and mental health. FINDINGS: Averages for sleep variables were: TST 7.1±1.11 hours and PSQI global sleep quality 7.5±3.2. Thirty-six percent reported less than 7 hours nocturnal sleep and 79% had a PSQI >= 5. Average QOL composite and domain scores ranged from 42.60-54.58; 14-71% of subjects scored below the norm across categories. Bivariate correlations (Spearman’s rho) indicated that TST was positively associated with the mental composite score (r=0.52, p=.05). Higher PSQI scores were associated with lower physical function (r=-0.55, p=.04), vitality (r=-0.52, p=.05), social function (r=-0.55, p=.04) and mental health (r=-0.679, p=.008) scores. CONCLUSIONS: Patients with advanced lung and colorectal cancer have poor nocturnal sleep quantity and quality that may be related to reductions in several QOL domains. IMPLICATIONS: As we enroll additional subjects, we will be able to further explore and characterize the association between self-reported quantity and quality of sleep and QOL in this population.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleSleep Disturbances and Quality of Life in Patients with Advanced Lung and Colorectal Canceren_GB
dc.identifier.urihttp://hdl.handle.net/10755/149138-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Sleep Disturbances and Quality of Life in Patients with Advanced Lung and Colorectal Cancer</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2003</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Vena, Catherine I., RN, MSN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Emory University</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Doctoral Candidate</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">cvena@emory.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Kathy P. Parker, PhD, RN, FAAN; Rebecca Allen, PhD; Donald L. Bliwise, PhD; Sanjay R. Jain, MD, PhD; Laura P. Kimble, PhD, RN</td></tr><tr><td colspan="2" class="item-abstract">OBJECTIVE: Since few studies have specifically focused on the impact of sleep quantity and quality on the quality of life (QOL) of advanced cancer patients, we are examining these variables in a cohort of patients with late-stage malignancy. DESIGN: Descriptive, correlational. SAMPLE: Fourteen stage IV colorectal (n = 7) or lung cancer (n = 7) outpatients (mean &plusmn; SD age 52.6&plusmn;12.68, range 28-69) who were cognitively intact, had no history of a sleep, neurologic, mood, anxiety or psychotic disorder, or known cerebral metastases. METHODS: Sleep variables (total sleep time &ndash; TST, subjective sleep quality) were measured by the Pittsburgh Sleep Quality Index (PSQI; score of &gt;=5 indicates sleep disturbance). QOL variables, measured by the Medical Outcomes Study Short Form 36, version 2 (SF36v2), included two summary and eight domain scores (population norm 50): physical composite, mental composite, physical function, role physical, bodily pain, general health, vitality, social function, role emotional and mental health. FINDINGS: Averages for sleep variables were: TST 7.1&plusmn;1.11 hours and PSQI global sleep quality 7.5&plusmn;3.2. Thirty-six percent reported less than 7 hours nocturnal sleep and 79% had a PSQI &gt;= 5. Average QOL composite and domain scores ranged from 42.60-54.58; 14-71% of subjects scored below the norm across categories. Bivariate correlations (Spearman&rsquo;s rho) indicated that TST was positively associated with the mental composite score (r=0.52, p=.05). Higher PSQI scores were associated with lower physical function (r=-0.55, p=.04), vitality (r=-0.52, p=.05), social function (r=-0.55, p=.04) and mental health (r=-0.679, p=.008) scores. CONCLUSIONS: Patients with advanced lung and colorectal cancer have poor nocturnal sleep quantity and quality that may be related to reductions in several QOL domains. IMPLICATIONS: As we enroll additional subjects, we will be able to further explore and characterize the association between self-reported quantity and quality of sleep and QOL in this population.</td></tr></table>en_GB
dc.date.available2011-10-26T09:56:49Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T09:56:49Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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