2.50
Hdl Handle:
http://hdl.handle.net/10755/149588
Type:
Presentation
Title:
Biobehavioral Interactions in Neuro-Oncology Caregivers
Abstract:
Biobehavioral Interactions in Neuro-Oncology Caregivers
Conference Sponsor:Sigma Theta Tau International
Conference Year:2007
Author:Sherwood, Paula R., PhD, RN, CNRN
P.I. Institution Name:University of Pittsburgh
Title:Assistant Professor
Co-Authors:Heidi Donovan, PhD, RN; Barbara A. Given, RN, PhD, FAAN; Allison Hricik, MS, BS; Catherine M. Bender, RN, PhD; Alyssa G. Newberry, ; Sarah Bradley, BS; Frank Lieberman, MD
[Clinical session research presentation] Although negative biological and behavioral responses have been identified in family caregivers, little research has examined bio-behavioral interactions in caregivers, particularly over the course of the care situation. The purpose of this longitudinal, descriptive pilot study, based on the Pittsburgh Mind Body Center Model, was to evaluate whether changes in caregivers' biological responses [measured by interleukin (IL) 1 and 6] are associated with changes in behavioral responses to care.  Ten adult caregivers (superscript 3) 21 years of age) of persons with a primary malignant brain tumor were recruited within one month of diagnosis. Data were collected at baseline and 3-months.  Behavioral responses (e.g. anxiety, sleep disturbance) were gathered via telephone interviews.  Specimens for IL-1 and IL-6 were obtained via venipuncture and analyzed using enzyme-linked immunosorbent assays.  Spearman's rho coefficients were generated and p equal to or greater than 07 was considered meaningful due to the small sample size.  Several bio-behavioral relationships were found.  A decrease in social support during the first three months following diagnosis was associated with an increase in IL-6 (r = -.87, p=.02).  Similarly, a decrease in caregivers' sleep quality was associated with an increase in IL-6 (r = -.90, p=.04).  An increase in caregiver anxiety was associated with an increase in IL-1 levels (r = .77, p=.07).  These preliminary data suggest caregivers may be at risk for altered immune function resulting from behavioral responses to the stress of providing care, which may occur as early as the first three months following the care recipient's diagnosis.  Data also underscore the importance of concomitantly assessing biological and behavioral phenomena when evaluating an individual's response to stress. Results may help health care practitioners identify which caregivers will suffer negative physical health as a result of the stress of providing care, so that interventions to lessen caregiver distress may be implemented.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleBiobehavioral Interactions in Neuro-Oncology Caregiversen_GB
dc.identifier.urihttp://hdl.handle.net/10755/149588-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Biobehavioral Interactions in Neuro-Oncology Caregivers</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2007</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Sherwood, Paula R., PhD, RN, CNRN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of Pittsburgh</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Assistant Professor</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">prs11@pitt.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Heidi Donovan, PhD, RN; Barbara A. Given, RN, PhD, FAAN; Allison Hricik, MS, BS; Catherine M. Bender, RN, PhD; Alyssa G. Newberry, ; Sarah Bradley, BS; Frank Lieberman, MD</td></tr><tr><td colspan="2" class="item-abstract">[Clinical session research presentation] Although negative biological and behavioral responses have been identified in family caregivers, little research has examined bio-behavioral interactions in caregivers, particularly over the course of the care situation. The purpose of this longitudinal, descriptive pilot study, based on the Pittsburgh Mind Body Center Model, was to evaluate whether changes in caregivers' biological responses [measured by interleukin (IL) 1 and 6] are associated with changes in behavioral responses to care.&nbsp; Ten adult caregivers (superscript 3) 21 years of age) of persons with a primary malignant brain tumor were recruited within one month of diagnosis.&nbsp;Data were collected at baseline and 3-months.&nbsp; Behavioral responses (e.g. anxiety, sleep disturbance) were gathered via telephone interviews.&nbsp; Specimens for IL-1 and IL-6 were obtained via venipuncture and analyzed using enzyme-linked immunosorbent assays.&nbsp; Spearman's rho coefficients were generated and p equal to or greater than 07 was considered meaningful due to the small sample size.&nbsp; Several bio-behavioral relationships were found.&nbsp; A decrease in social support during the first three months following diagnosis was associated with an increase in IL-6 (r = -.87, p=.02).&nbsp; Similarly, a decrease in caregivers' sleep quality was associated with an increase in IL-6 (r = -.90, p=.04).&nbsp; An increase in caregiver anxiety was associated with an increase in IL-1 levels (r = .77, p=.07).&nbsp; These preliminary data suggest caregivers may be at risk for altered immune function resulting from behavioral responses to the stress of providing care, which may occur as early as the first three months following the care recipient's diagnosis.&nbsp; Data also underscore the importance of concomitantly assessing biological and behavioral phenomena when evaluating an individual's response to stress.&nbsp;Results may help health care practitioners identify which caregivers will suffer negative physical health as a result of the stress of providing care, so that interventions to lessen caregiver distress may be implemented.</td></tr></table>en_GB
dc.date.available2011-10-26T10:05:26Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T10:05:26Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
All Items in this repository are protected by copyright, with all rights reserved, unless otherwise indicated.