Comparison of Glycerine Payayor and Benzydamine in Prevention and Relief of Oral Mucositis among Patients with Head and Neck Cancer Receiving Radiotherapy

2.50
Hdl Handle:
http://hdl.handle.net/10755/150700
Type:
Presentation
Title:
Comparison of Glycerine Payayor and Benzydamine in Prevention and Relief of Oral Mucositis among Patients with Head and Neck Cancer Receiving Radiotherapy
Abstract:
Comparison of Glycerine Payayor and Benzydamine in Prevention and Relief of Oral Mucositis among Patients with Head and Neck Cancer Receiving Radiotherapy
Conference Sponsor:Sigma Theta Tau International
Conference Year:2007
Author:Putwatana, Panwadee, DSc, RN
P.I. Institution Name:Faculty of Medicine Ramathibodi Hospital, Mahidol University
Title:Associate Professor
[Research Presentation] This study is a prospective, randomized clinical trial, aims to compare the efficacy of glycerine Payayor oral drop with Benzydamine mouth rinse in prevention and relief of oral mucositis in patients with head and neck cancer receiving radiotherapy. Sixty patients with cancer of head and/or neck who started to receive radiotherapy during a ten-month period from March to December 2005 who met the predetermined criteria were included in the study. The study was performed in an Out Patient Department of a tertiary care hospital, Bangkok, Thailand. Thirty patients were randomly assigned into each study group receiving glycerine Payayor or Benzydamine hydrochloride. Subject was followed up six times throughout the radiotherapy course. Glycerine Payayor is a finished-herb product, made in Thailand.áIt was dripped into the mouth or upon the lesion, while Benzydamine was used as mouth rinsing from the first to the last day of radiation or till the lesion was recovered. Oral status of each subject was recorded once weekly by a nurse-researcher, blind to the group, followed the WHO criteria during the treatment period and two weeks after. Other related factors, consequences of oral mucositis, and satisfaction with the solutions were also assessed. Comparison of each parameter between the two groups was performed by t-test. It was found that the average onset of oral mucositis was significantly later, its severity and pain score were significantly less throughout the study period in the glycerine Payayor group than the Benzydamine group. Significantly higher score of satisfaction of the solution, and higher body weight at the end of the study were shown in the same group. Glycerine Payayor is low price and no side effects found. It is recommended to use for prevention and relief of oral mucositis related to radiotherapy in adult and elder cancer patients.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleComparison of Glycerine Payayor and Benzydamine in Prevention and Relief of Oral Mucositis among Patients with Head and Neck Cancer Receiving Radiotherapyen_GB
dc.identifier.urihttp://hdl.handle.net/10755/150700-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Comparison of Glycerine Payayor and Benzydamine in Prevention and Relief of Oral Mucositis among Patients with Head and Neck Cancer Receiving Radiotherapy</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2007</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Putwatana, Panwadee, DSc, RN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Faculty of Medicine Ramathibodi Hospital, Mahidol University</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Associate Professor</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">rappw@mahidol.ac.th</td></tr><tr><td colspan="2" class="item-abstract">[Research Presentation] This study is a prospective, randomized clinical trial, aims to compare the efficacy of glycerine Payayor oral drop with Benzydamine mouth rinse in prevention and relief of oral mucositis in patients with head and neck cancer receiving radiotherapy. Sixty patients with cancer of head and/or neck who started to receive radiotherapy during a ten-month period from March to December 2005 who met the predetermined criteria were included in the study. The study was performed in an Out Patient Department of a tertiary care hospital, Bangkok, Thailand. Thirty patients were randomly assigned into each study group receiving glycerine Payayor or Benzydamine hydrochloride. Subject was followed up six times throughout the radiotherapy course. Glycerine Payayor is a finished-herb product, made in Thailand.&aacute;It was dripped into the mouth or upon the lesion, while Benzydamine was used as mouth rinsing from the first to the last day of radiation or till the lesion was recovered. Oral status of each subject was recorded once weekly by a nurse-researcher, blind to the group, followed the WHO criteria during the treatment period and two weeks after. Other related factors, consequences of oral mucositis, and satisfaction with the solutions were also assessed. Comparison of each parameter between the two groups was performed by t-test. It was found that the average onset of oral mucositis was significantly later, its severity and pain score were significantly less throughout the study period in the glycerine Payayor group than the Benzydamine group. Significantly higher score of satisfaction of the solution, and higher body weight at the end of the study were shown in the same group. Glycerine Payayor is low price and no side effects found. It is recommended to use for prevention and relief of oral mucositis related to radiotherapy in adult and elder cancer patients.</td></tr></table>en_GB
dc.date.available2011-10-26T10:40:28Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T10:40:28Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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