2.50
Hdl Handle:
http://hdl.handle.net/10755/151678
Type:
Presentation
Title:
Standardizing Intervention Protocols: Maintaining Treatment Integrity
Abstract:
Standardizing Intervention Protocols: Maintaining Treatment Integrity
Conference Sponsor:Sigma Theta Tau International
Conference Year:2004
Conference Date:July 22-24, 2004
Author:Mock, Victoria, DNSc, FAAN
P.I. Institution Name:Johns Hopkins University
Title:associate professor
Problem: One of the most important methodological challenges in any experimental research study is that of maintaining consistently uniform treatment for subjects throughout the study as the intervention is being tested. The challenge of maintaining treatment integrity is particularly difficult and essential to address successfully in multi-institutional research studies where several research sites are involved. Purpose: This presentation will discuss approaches to maintaining treatment integrity from the researcher’s experiences in intervention research from several multisite studies. Approach: The treatment or intervention being tested must be the same treatment, administered in the same fashion, to all subjects across all sites. Inconsistent treatment or variations in the treatments across sites or even within one site can reduce the effect size and make it more difficult to determine the power or efficacy of the intervention. If there is a dose-response relationship, subjects who receive less than the optimal amount or quality of the treatment will have a reduced response. This will increase the variance in the posttest measures within the experimental group. Increased variability within the groups can decrease the effect size of the intervention. Standardizing the intervention involves three fundamental concepts. One, a careful detailed protocol for administering the treatment; two, a rigorous training process for all the research team members who are applying the treatment; and three, a vigilant plan for monitoring the entire process. When we use a rapidly changing clinical setting for research, and vulnerable patients– rather than mice or microorganisms or DNA –as our subjects, whatever can go wrong often does. Implications: Therefore, it is essential to specify the protocol in detail, carefully train the team members, and vigilantly monitor all aspects of the intervention in order to maintain treatment integrity and accurately determine the true effects of the intervention.
Repository Posting Date:
26-Oct-2011
Date of Publication:
22-Jul-2004
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleStandardizing Intervention Protocols: Maintaining Treatment Integrityen_GB
dc.identifier.urihttp://hdl.handle.net/10755/151678-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Standardizing Intervention Protocols: Maintaining Treatment Integrity</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2004</td></tr><tr class="item-conference-date"><td class="label">Conference Date:</td><td class="value">July 22-24, 2004</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Mock, Victoria, DNSc, FAAN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Johns Hopkins University</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">associate professor</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">vmock@son.jhmi.edu</td></tr><tr><td colspan="2" class="item-abstract">Problem: One of the most important methodological challenges in any experimental research study is that of maintaining consistently uniform treatment for subjects throughout the study as the intervention is being tested. The challenge of maintaining treatment integrity is particularly difficult and essential to address successfully in multi-institutional research studies where several research sites are involved. Purpose: This presentation will discuss approaches to maintaining treatment integrity from the researcher&rsquo;s experiences in intervention research from several multisite studies. Approach: The treatment or intervention being tested must be the same treatment, administered in the same fashion, to all subjects across all sites. Inconsistent treatment or variations in the treatments across sites or even within one site can reduce the effect size and make it more difficult to determine the power or efficacy of the intervention. If there is a dose-response relationship, subjects who receive less than the optimal amount or quality of the treatment will have a reduced response. This will increase the variance in the posttest measures within the experimental group. Increased variability within the groups can decrease the effect size of the intervention. Standardizing the intervention involves three fundamental concepts. One, a careful detailed protocol for administering the treatment; two, a rigorous training process for all the research team members who are applying the treatment; and three, a vigilant plan for monitoring the entire process. When we use a rapidly changing clinical setting for research, and vulnerable patients&ndash; rather than mice or microorganisms or DNA &ndash;as our subjects, whatever can go wrong often does. Implications: Therefore, it is essential to specify the protocol in detail, carefully train the team members, and vigilantly monitor all aspects of the intervention in order to maintain treatment integrity and accurately determine the true effects of the intervention.</td></tr></table>en_GB
dc.date.available2011-10-26T11:10:04Z-
dc.date.issued2004-07-22en_GB
dc.date.accessioned2011-10-26T11:10:04Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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