Functional Limitations, Exercise, and Quality of Life: A Longitudinal Study of Persons With Multiple Sclerosis

2.50
Hdl Handle:
http://hdl.handle.net/10755/152583
Type:
Presentation
Title:
Functional Limitations, Exercise, and Quality of Life: A Longitudinal Study of Persons With Multiple Sclerosis
Abstract:
Functional Limitations, Exercise, and Quality of Life: A Longitudinal Study of Persons With Multiple Sclerosis
Conference Sponsor:Sigma Theta Tau International
Conference Year:2005
Author:Stuifbergen, Alexa, PhD, RN, FAAN
P.I. Institution Name:The University of Texas at Austin
Title:Professor, Associate Dean for Research
Co-Authors:Shelley Blozis, PhD; Tracie C. Harrison, PhD, MSN, RN, FNP; Heather Becker, PhD
During the last decade substantial progress has been made in defining the pathologic changes of multiple sclerosis (MS) and developing disease-modifying medications. However, little is known about the natural history of MS and specifically how functional limitations change over time, what factors influence the rate of change and the resulting impact on quality of life. The purpose of this study was to explore the trajectories of functional limitations, health behaviors (exercise) and perceived quality of life over a seven-year time period. A sample of 621 persons with MS enrolled in the longitudinal study and completed an annual questionnaire battery with instruments measuring demographic and illness characteristics, health-related attitudes and behaviors, and quality of life. At the start of the longitudinal study participants ranged in age from 21 to 81 (mean 50.44). The majority were female (83%), white/non Hispanic (93%), and married (73%). Most (85%) had completed high school and only 25 % were currently employed full-time. A multivariate latent curve model was estimated in which self-reports of functional limitations, exercise behaviors and quality of life scores were considered simultaneously to study the correlations between characteristics of change between the variables. Covariates (age, gender and years since diagnosis) were included in the model to study potential moderating effects of these variables on the correlations between change features in the repeated measures. Change in functional limitation scores were negatively correlated with change in exercise behaviors and quality of life scores (r = -.43 and r = -.66, respectively). Change in exercise behaviors and quality of life scores were positively correlated (r = .45). Longitudinal studies of functional limitations, disability, and quality of life offer an opportunity to gain critical information about the challenges that persons with MS face over time and identify potential moderators of the course of the disease-related limitations.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleFunctional Limitations, Exercise, and Quality of Life: A Longitudinal Study of Persons With Multiple Sclerosisen_GB
dc.identifier.urihttp://hdl.handle.net/10755/152583-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Functional Limitations, Exercise, and Quality of Life: A Longitudinal Study of Persons With Multiple Sclerosis</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2005</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Stuifbergen, Alexa, PhD, RN, FAAN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">The University of Texas at Austin</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Professor, Associate Dean for Research</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">astuifbergen@mail.utexas.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Shelley Blozis, PhD; Tracie C. Harrison, PhD, MSN, RN, FNP; Heather Becker, PhD</td></tr><tr><td colspan="2" class="item-abstract">During the last decade substantial progress has been made in defining the pathologic changes of multiple sclerosis (MS) and developing disease-modifying medications. However, little is known about the natural history of MS and specifically how functional limitations change over time, what factors influence the rate of change and the resulting impact on quality of life. The purpose of this study was to explore the trajectories of functional limitations, health behaviors (exercise) and perceived quality of life over a seven-year time period. A sample of 621 persons with MS enrolled in the longitudinal study and completed an annual questionnaire battery with instruments measuring demographic and illness characteristics, health-related attitudes and behaviors, and quality of life. At the start of the longitudinal study participants ranged in age from 21 to 81 (mean 50.44). The majority were female (83%), white/non Hispanic (93%), and married (73%). Most (85%) had completed high school and only 25 % were currently employed full-time. A multivariate latent curve model was estimated in which self-reports of functional limitations, exercise behaviors and quality of life scores were considered simultaneously to study the correlations between characteristics of change between the variables. Covariates (age, gender and years since diagnosis) were included in the model to study potential moderating effects of these variables on the correlations between change features in the repeated measures. Change in functional limitation scores were negatively correlated with change in exercise behaviors and quality of life scores (r = -.43 and r = -.66, respectively). Change in exercise behaviors and quality of life scores were positively correlated (r = .45). Longitudinal studies of functional limitations, disability, and quality of life offer an opportunity to gain critical information about the challenges that persons with MS face over time and identify potential moderators of the course of the disease-related limitations.</td></tr></table>en_GB
dc.date.available2011-10-26T11:41:44Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T11:41:44Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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