2.50
Hdl Handle:
http://hdl.handle.net/10755/152694
Type:
Presentation
Title:
Cardiovascular Risks in Youth With Diabetes: Homocysteine, Lipids, and Diet
Abstract:
Cardiovascular Risks in Youth With Diabetes: Homocysteine, Lipids, and Diet
Conference Sponsor:Sigma Theta Tau International
Conference Year:2004
Conference Date:July 22-24, 2004
Author:Faulkner, Melissa Spezia, BSN, MSN, DSN
P.I. Institution Name:University of Illinois at Chicago
Title:Associate Professor
Co-Authors:Wei-Hsun Chao, MS; Laurie Quinn, PhD; Cynthia Fritschi, MS, CDE; Robert D. Reynolds, PhD
Objective: The purposes of this study were to compare total homocysteine (tHcy), lipids, and dietary intake of macronutrients, folate, and vitamins B6 and B12 in adolescents with type 1 and type 2 diabetes (DM) and healthy controls. The influences of age, gender, and body mass index on tHcy were explored. Design: A cross-sectional, descriptive design was used. Population, Sample, Setting, Years: Subjects included adolescents: 50 with type 1 DM, 14 with type 2 DM, and 53 controls. The mean ages for those with type 1 vs. type 2 DM were 15.2 ± 1.9 years vs. 16.1 ± 1.9 years. The mean age for the controls was 16.5 ± 1.0 years. Youth with DM were recruited from the pediatric diabetes clinic of a major Midwestern medical center. Controls were recruited from a suburban high school in the same metropolitan area. Variables Studied Together: Variables included fasting tHcy and lipids, and 24-hour dietary recalls for macronutrients and micronutrients. Hemoglobin A1c was obtained for those with DM. Methods: Dietary data were analyzed using Nutritionist V (First Data Bank, San Bruno, CA). Lab assays were performed at university-based facilities. Statistical analyses included one-way analyses of variance, Pearson correlations, and stepwise regression. Findings: Adolescents with type 1 DM had the lowest tHcy values (P < 0.05). Age was the strongest predictor for higher tHcy (P < 0.001). Hemoglobin A1c was related to total cholesterol and triglycerides in those with type 1 DM. Conclusions: Lower tHcy in those with type 1 DM were consistent with the limited extant research with this population. Age variation in tHcy was similar to recent NHANES data. Implications: Further research is needed to determine the efficacy of using tHcy as a predictor of CV risks in youth with DM. Better metabolic control is suggested to lower lipids in youth with DM.
Repository Posting Date:
26-Oct-2011
Date of Publication:
22-Jul-2004
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleCardiovascular Risks in Youth With Diabetes: Homocysteine, Lipids, and Dieten_GB
dc.identifier.urihttp://hdl.handle.net/10755/152694-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Cardiovascular Risks in Youth With Diabetes: Homocysteine, Lipids, and Diet</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2004</td></tr><tr class="item-conference-date"><td class="label">Conference Date:</td><td class="value">July 22-24, 2004</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Faulkner, Melissa Spezia, BSN, MSN, DSN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of Illinois at Chicago</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Associate Professor</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">melissaf@uic.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Wei-Hsun Chao, MS; Laurie Quinn, PhD; Cynthia Fritschi, MS, CDE; Robert D. Reynolds, PhD</td></tr><tr><td colspan="2" class="item-abstract">Objective: The purposes of this study were to compare total homocysteine (tHcy), lipids, and dietary intake of macronutrients, folate, and vitamins B6 and B12 in adolescents with type 1 and type 2 diabetes (DM) and healthy controls. The influences of age, gender, and body mass index on tHcy were explored. Design: A cross-sectional, descriptive design was used. Population, Sample, Setting, Years: Subjects included adolescents: 50 with type 1 DM, 14 with type 2 DM, and 53 controls. The mean ages for those with type 1 vs. type 2 DM were 15.2 &plusmn; 1.9 years vs. 16.1 &plusmn; 1.9 years. The mean age for the controls was 16.5 &plusmn; 1.0 years. Youth with DM were recruited from the pediatric diabetes clinic of a major Midwestern medical center. Controls were recruited from a suburban high school in the same metropolitan area. Variables Studied Together: Variables included fasting tHcy and lipids, and 24-hour dietary recalls for macronutrients and micronutrients. Hemoglobin A1c was obtained for those with DM. Methods: Dietary data were analyzed using Nutritionist V (First Data Bank, San Bruno, CA). Lab assays were performed at university-based facilities. Statistical analyses included one-way analyses of variance, Pearson correlations, and stepwise regression. Findings: Adolescents with type 1 DM had the lowest tHcy values (P &lt; 0.05). Age was the strongest predictor for higher tHcy (P &lt; 0.001). Hemoglobin A1c was related to total cholesterol and triglycerides in those with type 1 DM. Conclusions: Lower tHcy in those with type 1 DM were consistent with the limited extant research with this population. Age variation in tHcy was similar to recent NHANES data. Implications: Further research is needed to determine the efficacy of using tHcy as a predictor of CV risks in youth with DM. Better metabolic control is suggested to lower lipids in youth with DM.</td></tr></table>en_GB
dc.date.available2011-10-26T11:46:11Z-
dc.date.issued2004-07-22en_GB
dc.date.accessioned2011-10-26T11:46:11Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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