A Systematic Review: The Effect of Continuous Sedation Versus Interruption of Sedation on the Incidence of Delirium in Adult Intensive Care Unit Patients with Mechanical Ventilation

2.50
Hdl Handle:
http://hdl.handle.net/10755/152780
Type:
Presentation
Title:
A Systematic Review: The Effect of Continuous Sedation Versus Interruption of Sedation on the Incidence of Delirium in Adult Intensive Care Unit Patients with Mechanical Ventilation
Abstract:
A Systematic Review: The Effect of Continuous Sedation Versus Interruption of Sedation on the Incidence of Delirium in Adult Intensive Care Unit Patients with Mechanical Ventilation
Conference Sponsor:Sigma Theta Tau International
Conference Year:2011
Author:Tsou, Yin Yin, MS
P.I. Institution Name:Taipei Veterans General Hospital
Title:Researcher
[22nd International Nursing Research Congress - Research Presentation] Purpose: To assess the effect of continuous sedation versus interruption of sedation on the incidence of delirium in adult
intensive care unit patients with mechanical ventilation.
Methods: We search the databases(the Cochrane library, MEDLINE, CINHAL and PsycINFO), supplemented by a
manual review of bibliographies of identified articles and discussion with recognized content experts.
Selection Criteria: All randomised controlled trials involving adult ventilated patients were undertaken. The intervention
was a interruption of sedation and the control intervention was continuous sedation. The outcome was the incidence of
delirium based on the Diagnostic and Statistical Manual of Mental Disorders or WHO ICD-10 classification criteria for
delirium. A critical appraisal and data extraction were performed by two reviewers.
Results: Two randomized controlled trials were identified. Only one study (336 participants) discussed the incidence of
delirium and reported no significant difference between the two study groups. Regarding length of hospital stay, one
study reported no difference between the two groups while the second study showed the intervention group was
discharged earlier than the control group.
Conclusion: There was insufficient evidence to draw firm conclusions about the positive effects of the interruption of
sedation in either the incidence of delirium or the length of stay in hospital. More high quality research is needed in order
to answer this research question
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleA Systematic Review: The Effect of Continuous Sedation Versus Interruption of Sedation on the Incidence of Delirium in Adult Intensive Care Unit Patients with Mechanical Ventilationen_GB
dc.identifier.urihttp://hdl.handle.net/10755/152780-
dc.description.abstract<table><tr><td colspan="2" class="item-title">A Systematic Review: The Effect of Continuous Sedation Versus Interruption of Sedation on the Incidence of Delirium in Adult Intensive Care Unit Patients with Mechanical Ventilation</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2011</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Tsou, Yin Yin, MS</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Taipei Veterans General Hospital</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Researcher</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">yytsou@vghtpe.gov.tw</td></tr><tr><td colspan="2" class="item-abstract">[22nd International Nursing Research Congress - Research Presentation] Purpose: To assess the effect of continuous sedation versus interruption of sedation on the incidence of delirium in adult<br/>intensive care unit patients with mechanical ventilation. <br/>Methods: We search the databases(the Cochrane library, MEDLINE, CINHAL and PsycINFO), supplemented by a<br/>manual review of bibliographies of identified articles and discussion with recognized content experts.<br/>Selection Criteria: All randomised controlled trials involving adult ventilated patients were undertaken. The intervention<br/>was a interruption of sedation and the control intervention was continuous sedation. The outcome was the incidence of<br/>delirium based on the Diagnostic and Statistical Manual of Mental Disorders or WHO ICD-10 classification criteria for<br/>delirium. A critical appraisal and data extraction were performed by two reviewers. <br/>Results: Two randomized controlled trials were identified. Only one study (336 participants) discussed the incidence of<br/>delirium and reported no significant difference between the two study groups. Regarding length of hospital stay, one<br/>study reported no difference between the two groups while the second study showed the intervention group was<br/>discharged earlier than the control group. <br/>Conclusion: There was insufficient evidence to draw firm conclusions about the positive effects of the interruption of<br/>sedation in either the incidence of delirium or the length of stay in hospital. More high quality research is needed in order<br/>to answer this research question</td></tr></table>en_GB
dc.date.available2011-10-26T11:49:31Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T11:49:31Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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