The Effects of Music on Circulating Cytokine Levels: A Randomized Controlled Trial

2.50
Hdl Handle:
http://hdl.handle.net/10755/153802
Type:
Presentation
Title:
The Effects of Music on Circulating Cytokine Levels: A Randomized Controlled Trial
Abstract:
The Effects of Music on Circulating Cytokine Levels: A Randomized Controlled Trial
Conference Sponsor:Sigma Theta Tau International
Conference Year:2011
Author:Lai, Hui-Ling, BSN, MPH, MS(PH), PhD, RN
P.I. Institution Name:Tzu Chi University/ Buddhist Tzu Chi General Hospital
Title:Associate Professor / Vice Director
[2nd International Nursing Research Conference for the World Academy of Nursing Science - Presentation] Purpose: To examine the effects of various types of music and quiet rest on the modulation of interleukin-6(IL-6), tumor necrosis factor-alpha (TNF-alpha), interleukin-10 (IL-10), heart rate, and mean arterial pressure among first-line nurses. The secondary purpose was to examine the music preferences of the two music groups.
Method: Using a three-group pretest-post test design during the period March to June 2007, 60 nurses, age 21?42 years, who worked in a hospital were randomly assigned to each group. Participants in the stimulating or sedating music groups listened to stimulating music or sedating music for 30 minutes. In the rest group, subjects sat quietly for 30 minutes. Participants? physiological and psychoneuroimmunological parameters were measured using a blood pressure monitor and enzyme linked immunosorbent assays. General estimating equation (GEE) was used to analyze data.
Results: After controlling for confounding factors, significant differences in IL-6 and IL-10 levels among groups were found (p = 0.021?0.001). Sedating music had greatest effect on decreasing plasma IL-6 levels, with the greatest increase of IL-10 levels in the quiet rest group. Stimulating music also had greatest effect on increasing MAP (p = 0.04). The sedating music group had significantly higher scores for music preference than in the stimulating music group (p = 0.013).
Conclusions: Sedating music, stimulating music, and quiet rest had immunomodulatory effects manifested in circulating IL-6 and IL-10 levels, with no significant change in TNF-a production. Any continuous effect, and whether or not it facilitates adaptation to future stress, requires further research. For the reason of gender differences in the prevalence of inflammatory disorders, future studies were suggested to speculate on gender disparities for the effect of music on cytokine production.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleThe Effects of Music on Circulating Cytokine Levels: A Randomized Controlled Trialen_GB
dc.identifier.urihttp://hdl.handle.net/10755/153802-
dc.description.abstract<table><tr><td colspan="2" class="item-title">The Effects of Music on Circulating Cytokine Levels: A Randomized Controlled Trial</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2011</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Lai, Hui-Ling, BSN, MPH, MS(PH), PhD, RN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Tzu Chi University/ Buddhist Tzu Chi General Hospital</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Associate Professor / Vice Director</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">snowjade@mail.tcu.edu.tw</td></tr><tr><td colspan="2" class="item-abstract">[2nd International Nursing Research Conference for the World Academy of Nursing Science - Presentation] Purpose: To examine the effects of various types of music and quiet rest on the modulation of interleukin-6(IL-6), tumor necrosis factor-alpha (TNF-alpha), interleukin-10 (IL-10), heart rate, and mean arterial pressure among first-line nurses. The secondary purpose was to examine the music preferences of the two music groups. <br/>Method: Using a three-group pretest-post test design during the period March to June 2007, 60 nurses, age 21?42 years, who worked in a hospital were randomly assigned to each group. Participants in the stimulating or sedating music groups listened to stimulating music or sedating music for 30 minutes. In the rest group, subjects sat quietly for 30 minutes. Participants? physiological and psychoneuroimmunological parameters were measured using a blood pressure monitor and enzyme linked immunosorbent assays. General estimating equation (GEE) was used to analyze data. <br/>Results: After controlling for confounding factors, significant differences in IL-6 and IL-10 levels among groups were found (p = 0.021?0.001). Sedating music had greatest effect on decreasing plasma IL-6 levels, with the greatest increase of IL-10 levels in the quiet rest group. Stimulating music also had greatest effect on increasing MAP (p = 0.04). The sedating music group had significantly higher scores for music preference than in the stimulating music group (p = 0.013). <br/>Conclusions: Sedating music, stimulating music, and quiet rest had immunomodulatory effects manifested in circulating IL-6 and IL-10 levels, with no significant change in TNF-a production. Any continuous effect, and whether or not it facilitates adaptation to future stress, requires further research. For the reason of gender differences in the prevalence of inflammatory disorders, future studies were suggested to speculate on gender disparities for the effect of music on cytokine production.</td></tr></table>en_GB
dc.date.available2011-10-26T12:31:38Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T12:31:38Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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