2.50
Hdl Handle:
http://hdl.handle.net/10755/153904
Type:
Presentation
Title:
Impact of Resistance Training on Balance in Multiple Sclerosis Patients
Abstract:
Impact of Resistance Training on Balance in Multiple Sclerosis Patients
Conference Sponsor:Sigma Theta Tau International
Conference Year:2008
Author:Filipi, Mary L., PhD, APRN, RN, BSN, MSN
P.I. Institution Name:University of Nebraska Medical Center
Title:Assistant Professor
[Research Paper or Poster Presentation] The purpose of this study is to test the hypothesis that standardized, structured resistance training programs will improve balance outcome measures in Multiple Sclerosis (MS) patients with differing levels of gait and balance problems. Secondary goals compare accuracy and precision of different balance measures in the MS population and evaluate the effect of resistance training on disease progression, fatigue and immuno-regulatory biomarkers. For over 12 years, pharamacologic therapy has effectively decreased the number and severity of MS relapses. However, MS patients continue to experience disease progression, fatigue, muscle weakness and balance problems. Physical rehabilitation has shown positive effect in MS patients. Early studies did not evaluate resistance or strength training programs because of the perception that they exacerbate the fatigue associated with MS. These studies also did not evaluate traditional strength outcome measures to determine how best to monitor changes in balance and fatigue in this population. Current clinical measures are limited and reliability of these measures is unknown. This unique collaborative study is being done in conjunction with physical therapy, a research grade gait lab and a private training gym. Forty five subjects are being stratified into 3 groups on the basis of disability: Group 1, no clinical evidence of mobility problems; Group 2, minimal mobility and balance problems and Group 3, moderate mobility and balance problems. Evaluation is at baseline, as well as 3 and 6 months after enrollment in a weight resistance program. The groups are evaluated separately for improvement in strength and balance and any correlation between any change in strength and balance. Secondary outcome measures include fatigue level, disease progression, general balance and circulating inflammatory biomarkers. Balance is measured by the current clinical tool, the Balance Master, and a biomechanics evaluation using a Vicon-Peak high speed system and Kistler force platform. Interim analysis is reviewed.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleImpact of Resistance Training on Balance in Multiple Sclerosis Patientsen_GB
dc.identifier.urihttp://hdl.handle.net/10755/153904-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Impact of Resistance Training on Balance in Multiple Sclerosis Patients</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2008</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Filipi, Mary L., PhD, APRN, RN, BSN, MSN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of Nebraska Medical Center</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Assistant Professor</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">mfilipi@unmc.edu</td></tr><tr><td colspan="2" class="item-abstract">[Research Paper or Poster Presentation] The purpose of this study is to test the hypothesis that standardized, structured resistance training programs will improve balance outcome measures in Multiple Sclerosis (MS) patients with differing levels of gait and balance problems. Secondary goals compare accuracy and precision of different balance measures in the MS population and evaluate the effect of resistance training on disease progression, fatigue and immuno-regulatory biomarkers. For over 12 years, pharamacologic therapy has effectively decreased the number and severity of MS relapses. However, MS patients continue to experience disease progression, fatigue, muscle weakness and balance problems. Physical rehabilitation has shown positive effect in MS patients. Early studies did not evaluate resistance or strength training programs because of the perception that they exacerbate the fatigue associated with MS. These studies also did not evaluate traditional strength outcome measures to determine how best to monitor changes in balance and fatigue in this population. Current clinical measures are limited and reliability of these measures is unknown. This unique collaborative study is being done in conjunction with physical therapy, a research grade gait lab and a private training gym. Forty five subjects are being stratified into 3 groups on the basis of disability: Group 1, no clinical evidence of mobility problems; Group 2, minimal mobility and balance problems and Group 3, moderate mobility and balance problems. Evaluation is at baseline, as well as 3 and 6 months after enrollment in a weight resistance program. The groups are evaluated separately for improvement in strength and balance and any correlation between any change in strength and balance. Secondary outcome measures include fatigue level, disease progression, general balance and circulating inflammatory biomarkers. Balance is measured by the current clinical tool, the Balance Master, and a biomechanics evaluation using a Vicon-Peak high speed system and Kistler force platform. Interim analysis is reviewed.</td></tr></table>en_GB
dc.date.available2011-10-26T12:36:01Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T12:36:01Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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