A Randomized Controlled Trial to Compare Effectiveness of Nylon Stitches Versus Dermabond (2-Octyl Cyanoacrylate) in Closing Laceration Wounds in Emergency Departments

2.50
Hdl Handle:
http://hdl.handle.net/10755/154097
Type:
Presentation
Title:
A Randomized Controlled Trial to Compare Effectiveness of Nylon Stitches Versus Dermabond (2-Octyl Cyanoacrylate) in Closing Laceration Wounds in Emergency Departments
Abstract:
A Randomized Controlled Trial to Compare Effectiveness of Nylon Stitches Versus Dermabond (2-Octyl Cyanoacrylate) in Closing Laceration Wounds in Emergency Departments
Conference Sponsor:Sigma Theta Tau International
Conference Year:2008
Author:Lau, Ping Fat, MPhil, BSN, RN
P.I. Institution Name:Pamela Youde Nethersole Eastern Hospital
Title:Nurse Specialist
Co-Authors:Eliza Wong
[Research Paper or Poster Presentation] Question: Is tissue adhesive (Dermabond) as effective as ordinary nylon stitches in closing laceration wounds? Method: A randomized (allocation concealed), unblinded, controlled trial design was adopted. Patients who meet inclusion criteria (>16 years old, ambulatory, able to use visual analogue scale, with acute laceration wound < 8 cm with no bony, joint, neurovascular damage & wound closure performed by nurses) were invited to join the study voluntarily. Consenting patients were randomly assigned to either nylon or Dermabond group. Wounds of control group were closed as usual using ordinary nylon stitches. Wounds of treatment group were closed by applying Dermabond. All patients returned for wound review on day 14 by the trained wound assessors. Primary outcomes: æwound evaluation score' rated by assessors, and æcosmetic appearance score' determined by patients Secondary outcomes: æprocedure time' and æoverall satisfaction score' Results: 193 subjects from two hospitals were recruited initially. Only 186 patients (N=186) completed the process with 90 (48.4%) in control arm and 96 (51.6%) in treatment arm. The drop out rate was 3.8%. Between groups homogeneity was identified in demographic variables like age, sex, mechanism of injury, wound length, wound life and past health. At D14 review by wound assessors, no significant difference was identified in wound appearance (P =0.27). However, patients expressed significantly higher overall satisfaction level (91.3 VS 85.2, P<0.005) & cosmetic appearance score (84.6 VS 74.9, p<0.05) for patients in Dermabond group than nylon group. Procedure time in treatment group was significantly shorter than control group by 6 minutes (p<0.05). Conclusion: Dermabond is comparable to nylon stitches as an alternative wound closure material that equally effective in cosmetic outcome perceived by patients and health care professionals. Use of Dermabond could reduce procedure time significantly which, no doubt beneficial to patients as well as the cost of nursing time concerned.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleA Randomized Controlled Trial to Compare Effectiveness of Nylon Stitches Versus Dermabond (2-Octyl Cyanoacrylate) in Closing Laceration Wounds in Emergency Departmentsen_GB
dc.identifier.urihttp://hdl.handle.net/10755/154097-
dc.description.abstract<table><tr><td colspan="2" class="item-title">A Randomized Controlled Trial to Compare Effectiveness of Nylon Stitches Versus Dermabond (2-Octyl Cyanoacrylate) in Closing Laceration Wounds in Emergency Departments</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2008</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Lau, Ping Fat, MPhil, BSN, RN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Pamela Youde Nethersole Eastern Hospital</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Nurse Specialist</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">pflau@hotmail.com</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Eliza Wong</td></tr><tr><td colspan="2" class="item-abstract">[Research Paper or Poster Presentation] Question: Is tissue adhesive (Dermabond) as effective as ordinary nylon stitches in closing laceration wounds? Method: A randomized (allocation concealed), unblinded, controlled trial design was adopted. Patients who meet inclusion criteria (&gt;16 years old, ambulatory, able to use visual analogue scale, with acute laceration wound &lt; 8 cm with no bony, joint, neurovascular damage &amp; wound closure performed by nurses) were invited to join the study voluntarily. Consenting patients were randomly assigned to either nylon or Dermabond group. Wounds of control group were closed as usual using ordinary nylon stitches. Wounds of treatment group were closed by applying Dermabond. All patients returned for wound review on day 14 by the trained wound assessors. Primary outcomes: &aelig;wound evaluation score' rated by assessors, and &aelig;cosmetic appearance score' determined by patients Secondary outcomes: &aelig;procedure time' and &aelig;overall satisfaction score' Results: 193 subjects from two hospitals were recruited initially. Only 186 patients (N=186) completed the process with 90 (48.4%) in control arm and 96 (51.6%) in treatment arm. The drop out rate was 3.8%. Between groups homogeneity was identified in demographic variables like age, sex, mechanism of injury, wound length, wound life and past health. At D14 review by wound assessors, no significant difference was identified in wound appearance (P =0.27). However, patients expressed significantly higher overall satisfaction level (91.3 VS 85.2, P&lt;0.005) &amp; cosmetic appearance score (84.6 VS 74.9, p&lt;0.05) for patients in Dermabond group than nylon group. Procedure time in treatment group was significantly shorter than control group by 6 minutes (p&lt;0.05). Conclusion: Dermabond is comparable to nylon stitches as an alternative wound closure material that equally effective in cosmetic outcome perceived by patients and health care professionals. Use of Dermabond could reduce procedure time significantly which, no doubt beneficial to patients as well as the cost of nursing time concerned.</td></tr></table>en_GB
dc.date.available2011-10-26T12:44:31Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T12:44:31Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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