The Effect of Long-Term Depot Medroxyprogesterone (DMPA) use on Bone Mineral Density in Bangladeshi Women Under Age 21

2.50
Hdl Handle:
http://hdl.handle.net/10755/154916
Type:
Presentation
Title:
The Effect of Long-Term Depot Medroxyprogesterone (DMPA) use on Bone Mineral Density in Bangladeshi Women Under Age 21
Abstract:
The Effect of Long-Term Depot Medroxyprogesterone (DMPA) use on Bone Mineral Density in Bangladeshi Women Under Age 21
Conference Sponsor:Sigma Theta Tau International
Conference Year:2006
Author:Britt, Robin B., EdD, RNC
P.I. Institution Name:Texas Woman's University
Title:Professor
Co-Authors:Nahid J. Rianon, MD
PURPOSE:  The purpose of this cross-sectional, descriptive study was to determine if significant bone loss occurred in long-term (>2 years) Bangladeshi DMPA users who began depot medroxyprogesterone (DMPA) use in their adolescent years as compared to a non-hormonal control group matched for ethnicity (Bangladeshi), height, weight, BMI, nutritional diary intake and economic status. METHODS: One hundred married women in Dhaka, Bangladesh were recruited for this study.  Participants were clients in two reproductive health clinics who were divided into cases (n =50) (age 15-21) and controls (n = 50) (age 13-21) by DMPA history. A demographic questionnaire and a bone mineral density (BMD) scan were used for data collection.  After consent and questionnaire completion the participants had a bone mineral density (BMD) scan on their hip and spine. RESULTS:  A t-test revealed both the mean dexa lumbar spine scores (t=.160, df=98, p=.873) and mean femoral scores (t=-.145, df=98, p=.885) were not statistically significantly different. The BMD mean scores of both groups were low but not osteopenic.  A Pearson?s correlation between duration on DMPA and either lumbar dexa (r=.053, p=.716) or femoral dexa score (r=.038, p=.792) showed no relationship. CONCLUSIONS:  These results suggest that in this homogenous sample of adolescents, with low BMD there was no significant difference in BMD and no relationship between time on DMPA and BMD.  These findings conflict with some investigations and concur with others.  Further study is needed to validate the effects of DMPA on bone density in adolescents in both developing and developed countries.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleThe Effect of Long-Term Depot Medroxyprogesterone (DMPA) use on Bone Mineral Density in Bangladeshi Women Under Age 21en_GB
dc.identifier.urihttp://hdl.handle.net/10755/154916-
dc.description.abstract<table><tr><td colspan="2" class="item-title">The Effect of Long-Term Depot Medroxyprogesterone (DMPA) use on Bone Mineral Density in Bangladeshi Women Under Age 21</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2006</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Britt, Robin B., EdD, RNC</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Texas Woman's University</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Professor</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">rbritt@twu.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Nahid J. Rianon, MD</td></tr><tr><td colspan="2" class="item-abstract">PURPOSE: &nbsp;The purpose of this cross-sectional, descriptive study was to determine if significant bone loss occurred in long-term (&gt;2 years) Bangladeshi DMPA users who began depot medroxyprogesterone (DMPA) use in their adolescent years as compared to a non-hormonal control group matched for ethnicity (Bangladeshi), height, weight, BMI, nutritional diary intake and economic status. METHODS: One hundred married women in Dhaka, Bangladesh were recruited for this study.&nbsp; Participants were clients in two reproductive health clinics who were divided into cases (n =50) (age 15-21) and controls (n = 50) (age 13-21) by DMPA history. A demographic questionnaire and a bone mineral density (BMD) scan were used for data collection.&nbsp; After consent and questionnaire completion the participants had a bone mineral density (BMD) scan on their hip and spine. RESULTS:&nbsp; A t-test revealed both the mean dexa lumbar spine scores (t=.160, df=98, p=.873) and mean femoral scores (t=-.145, df=98, p=.885) were not statistically significantly different. The BMD mean scores of both groups were low but not osteopenic.&nbsp; A Pearson?s correlation between duration on DMPA and either lumbar dexa (r=.053, p=.716) or femoral dexa score (r=.038, p=.792) showed no relationship. CONCLUSIONS:&nbsp; These results suggest that in this homogenous sample of adolescents, with low BMD there was no significant difference in BMD and no relationship between time on DMPA and BMD.&nbsp; These findings conflict with some investigations and concur with others.&nbsp; Further study is needed to validate the effects of DMPA on bone density in adolescents in both developing and developed countries.</td></tr></table>en_GB
dc.date.available2011-10-26T13:22:57Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T13:22:57Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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