2.50
Hdl Handle:
http://hdl.handle.net/10755/156763
Type:
Presentation
Title:
Oxygen therapy: Harmful to patients with obstructive sleep apnea
Abstract:
Oxygen therapy: Harmful to patients with obstructive sleep apnea
Conference Sponsor:Sigma Theta Tau International
Conference Year:1992
Conference Date:August 6 - 8, 1992
Author:Cammermeyer, Margarethe, PhD
P.I. Institution Name:American Lake VAMC
Title:Clinical Nurse Specialist
Sleep apnea occurs in approximately 40 percent of males over 60

years of age. It results in disrupted and disrupting sleep,

deteriorating day time functioning and alertness and

physiologically contributes to hypertension, cardiac arrhythmias

and sudden death. As the disorder becomes more severe the episodes

of apnea become associated with hypoxemia which currently is

empirically treated with low flow oxygen. This study reports on

the adverse affect of oxygen therapy in subjects with obstructive

sleep apnea even though the hypoxemia is reversed.



Eleven male subjects participated in a 23 day, experimental,

randomized study comparing low flow oxygen therapy to continuous

positive airway pressure (CPAP) therapy for the purpose of

reversing hypoxemia, sleep fragmentation and apnea/hypopnea.

Subjects were monitored with six hours of polysomnography and

oximetry before and after one week treatment with low flow oxygen,

one week without treatment and then one week with CPAP treatment or

the reversed sequence.



Low flow oxygen therapy reversed the hypoxemia, increased the mean

apnea/hypopnea index and did not alter the mean sleep arousal

index. CPAP therapy reversed hypoxemia and nearly obliterated the

apnea/hypopnea and sleep arousals.



Apnea/Hypopnea Index, Oxygen Desaturation and Sleep Arousal Index

Before and After One Week with Oxygen and Continuous Positive

Airway Pressure (N=11)



PreOxygen Oxygen PreCPAP CPAP

AHI 53 56 52 4*

%TST<90 Sat 26 4 22 2*

SAI 50 46 47 9*

*p<.05



Nurses are in a unique position to assess patients during sleep and

identify sleep disordered breathing. They are also frequently

required to determine the appropriateness of oxygen therapy in

patients who are hypoxemic or whose cardiac status is being

monitored. This study again illustrates the importance of research

to determine the appropriateness of historical practice.



Repository Posting Date:
26-Oct-2011
Date of Publication:
6-Aug-1992
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleOxygen therapy: Harmful to patients with obstructive sleep apneaen_GB
dc.identifier.urihttp://hdl.handle.net/10755/156763-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Oxygen therapy: Harmful to patients with obstructive sleep apnea</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Sigma Theta Tau International</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">1992</td></tr><tr class="item-conference-date"><td class="label">Conference Date:</td><td class="value">August 6 - 8, 1992</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Cammermeyer, Margarethe, PhD</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">American Lake VAMC</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Clinical Nurse Specialist</td></tr><tr><td colspan="2" class="item-abstract">Sleep apnea occurs in approximately 40 percent of males over 60<br/><br/>years of age. It results in disrupted and disrupting sleep,<br/><br/>deteriorating day time functioning and alertness and<br/><br/>physiologically contributes to hypertension, cardiac arrhythmias<br/><br/>and sudden death. As the disorder becomes more severe the episodes<br/><br/>of apnea become associated with hypoxemia which currently is<br/><br/>empirically treated with low flow oxygen. This study reports on<br/><br/>the adverse affect of oxygen therapy in subjects with obstructive<br/><br/>sleep apnea even though the hypoxemia is reversed.<br/><br/><br/><br/>Eleven male subjects participated in a 23 day, experimental,<br/><br/>randomized study comparing low flow oxygen therapy to continuous<br/><br/>positive airway pressure (CPAP) therapy for the purpose of<br/><br/>reversing hypoxemia, sleep fragmentation and apnea/hypopnea.<br/><br/>Subjects were monitored with six hours of polysomnography and<br/><br/>oximetry before and after one week treatment with low flow oxygen,<br/><br/>one week without treatment and then one week with CPAP treatment or<br/><br/>the reversed sequence.<br/><br/><br/><br/>Low flow oxygen therapy reversed the hypoxemia, increased the mean<br/><br/>apnea/hypopnea index and did not alter the mean sleep arousal<br/><br/>index. CPAP therapy reversed hypoxemia and nearly obliterated the<br/><br/>apnea/hypopnea and sleep arousals.<br/><br/><br/><br/>Apnea/Hypopnea Index, Oxygen Desaturation and Sleep Arousal Index<br/><br/>Before and After One Week with Oxygen and Continuous Positive<br/><br/>Airway Pressure (N=11)<br/><br/><br/><br/> PreOxygen Oxygen PreCPAP CPAP<br/><br/>AHI 53 56 52 4*<br/><br/>%TST&lt;90 Sat 26 4 22 2*<br/><br/>SAI 50 46 47 9*<br/><br/>*p&lt;.05<br/><br/><br/><br/>Nurses are in a unique position to assess patients during sleep and<br/><br/>identify sleep disordered breathing. They are also frequently<br/><br/>required to determine the appropriateness of oxygen therapy in<br/><br/>patients who are hypoxemic or whose cardiac status is being<br/><br/>monitored. This study again illustrates the importance of research<br/><br/>to determine the appropriateness of historical practice.<br/><br/><br/><br/></td></tr></table>en_GB
dc.date.available2011-10-26T15:06:47Z-
dc.date.issued1992-08-06en_GB
dc.date.accessioned2011-10-26T15:06:47Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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