The Evaluation of Neuroendocrine Measures and Central Nervous System Responsiveness in Women with Diarrhea Predominant Irritable Bowel Syndrome

2.50
Hdl Handle:
http://hdl.handle.net/10755/158268
Type:
Presentation
Title:
The Evaluation of Neuroendocrine Measures and Central Nervous System Responsiveness in Women with Diarrhea Predominant Irritable Bowel Syndrome
Abstract:
The Evaluation of Neuroendocrine Measures and Central Nervous System Responsiveness in Women with Diarrhea Predominant Irritable Bowel Syndrome
Conference Sponsor:Western Institute of Nursing
Conference Year:2002
Author:FitzGerald, Leah
P.I. Institution Name:University of California-Los Angeles
Contact Address:100 Medical Plaza, Suite 255, Los Angeles, CA, 90095, USA
Contact Telephone:310.794.2277
To date, levels of CRF and NE in cerebrospinal fluid (CSF) of patients with IBS have not been reported. The purpose of this study is aimed at investigating if CRF and NE levels in CSF are increased in a subset of diarrhea predominant female IBS patients compared with matched control subjects, 2) if these levels correlate with peripheral measures of neuroendocrine activity and 3) if these levels correlate with IBS symptom severity and stress history. The conceptual framework is based on the upregulation of the interaction between corticotrophin releasing hormone (CRH) and noradrenergic neurons in the brain. A cross-sectional design will be used to describe and compare various neuroendocrine measures in 15 IBS diarrhea predominant women and 15 sex and age matched control subjects. The study will be completed at the University of California, Los Angeles Medical Center Clinical Research Unit.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Western Institute of Nursing

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleThe Evaluation of Neuroendocrine Measures and Central Nervous System Responsiveness in Women with Diarrhea Predominant Irritable Bowel Syndromeen_GB
dc.identifier.urihttp://hdl.handle.net/10755/158268-
dc.description.abstract<table><tr><td colspan="2" class="item-title">The Evaluation of Neuroendocrine Measures and Central Nervous System Responsiveness in Women with Diarrhea Predominant Irritable Bowel Syndrome</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Western Institute of Nursing</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2002</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">FitzGerald, Leah</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of California-Los Angeles</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">100 Medical Plaza, Suite 255, Los Angeles, CA, 90095, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">310.794.2277</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">lfitzgerald@mednet.ucla.edu</td></tr><tr><td colspan="2" class="item-abstract">To date, levels of CRF and NE in cerebrospinal fluid (CSF) of patients with IBS have not been reported. The purpose of this study is aimed at investigating if CRF and NE levels in CSF are increased in a subset of diarrhea predominant female IBS patients compared with matched control subjects, 2) if these levels correlate with peripheral measures of neuroendocrine activity and 3) if these levels correlate with IBS symptom severity and stress history. The conceptual framework is based on the upregulation of the interaction between corticotrophin releasing hormone (CRH) and noradrenergic neurons in the brain. A cross-sectional design will be used to describe and compare various neuroendocrine measures in 15 IBS diarrhea predominant women and 15 sex and age matched control subjects. The study will be completed at the University of California, Los Angeles Medical Center Clinical Research Unit.</td></tr></table>en_GB
dc.date.available2011-10-26T20:40:38Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T20:40:38Z-
dc.description.sponsorshipWestern Institute of Nursingen_GB
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