2.50
Hdl Handle:
http://hdl.handle.net/10755/158601
Type:
Presentation
Title:
Preventing Osteoporosis in Postmenopausal Breast Cancer Survivors
Abstract:
Preventing Osteoporosis in Postmenopausal Breast Cancer Survivors
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2002
Author:Waltman, Nancy
P.I. Institution Name:University of Nebraska Medical Center
Title:Associate Professor
Contact Address:College of Nursing, 113 Fairfield Hall, PO Box 880620, Lincoln, NE, 68588-0620, USA
Contact Telephone:402.472.7354
Breast cancer survivors are at risk for osteoporosis because women with a history of estrogen positive tumors are not candidates for hormone replacement therapy (HRT). After menopause and without HRT, bone loss occurs rapidly. This study examined the feasibility of a 12 month intervention [alendronate (5 to 10 mg/day), calcium (1500 mg/day), vitamin D (400 IU/day), and strength/weight training exercises] for preventing osteoporosis in postmenopausal breast cancer survivors. Facilitative strategies based on Prochaska's transtheoretical model promoted adherence to the intervention. Data were analyzed for 22 women, and at 12 months mean adherence rates for exercises was 79.4%, calcium/vitamin D, 94.8%, and alendronate, 95.6%. Changes in lbs lifted with exercises were significant (mean lbs lifted for the biceps curl (arm exercise) was 4.75 lbs (SD=3.5) at baseline and l2.00 lbs (SD=4.2) at 12 months (t=3.5, p=.037), and for the knee extension (leg exercise) was 4.5 lbs (SD=5.0) at baseline and 18.25 lbs (SD=4.0) at 12 months (t=8.9, p=.003). However, subjects were slower than anticipated in progressively lifting heavier weights. For example, for the biceps curl, 5 women lifted less than 10 lbs at 12 months and only 2 women progressed to 20 lb hand weights. At 12 months, muscle strength in the hip improved significantly (t=3.7, p=.002) and there was some improvement (not significant) for the knee and wrist. Mean percent change in bone mineral density (BMD, gm/cm2) for the spine was +2.49%, the hip +2.55%, and the forearm -2.46%. Increases in BMD at the spine and hip were not significant and women lost BMD in the forearm; however, without HRT, postmenopausal women are likely to lose bone every year. This intervention may be an effective alternative to HRT for preventing osteoporosis in postmenopausal breast cancer survivors.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titlePreventing Osteoporosis in Postmenopausal Breast Cancer Survivorsen_GB
dc.identifier.urihttp://hdl.handle.net/10755/158601-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Preventing Osteoporosis in Postmenopausal Breast Cancer Survivors</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2002</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Waltman, Nancy</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of Nebraska Medical Center</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Associate Professor</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">College of Nursing, 113 Fairfield Hall, PO Box 880620, Lincoln, NE, 68588-0620, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">402.472.7354</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">nwaltman@unmc.edu</td></tr><tr><td colspan="2" class="item-abstract">Breast cancer survivors are at risk for osteoporosis because women with a history of estrogen positive tumors are not candidates for hormone replacement therapy (HRT). After menopause and without HRT, bone loss occurs rapidly. This study examined the feasibility of a 12 month intervention [alendronate (5 to 10 mg/day), calcium (1500 mg/day), vitamin D (400 IU/day), and strength/weight training exercises] for preventing osteoporosis in postmenopausal breast cancer survivors. Facilitative strategies based on Prochaska's transtheoretical model promoted adherence to the intervention. Data were analyzed for 22 women, and at 12 months mean adherence rates for exercises was 79.4%, calcium/vitamin D, 94.8%, and alendronate, 95.6%. Changes in lbs lifted with exercises were significant (mean lbs lifted for the biceps curl (arm exercise) was 4.75 lbs (SD=3.5) at baseline and l2.00 lbs (SD=4.2) at 12 months (t=3.5, p=.037), and for the knee extension (leg exercise) was 4.5 lbs (SD=5.0) at baseline and 18.25 lbs (SD=4.0) at 12 months (t=8.9, p=.003). However, subjects were slower than anticipated in progressively lifting heavier weights. For example, for the biceps curl, 5 women lifted less than 10 lbs at 12 months and only 2 women progressed to 20 lb hand weights. At 12 months, muscle strength in the hip improved significantly (t=3.7, p=.002) and there was some improvement (not significant) for the knee and wrist. Mean percent change in bone mineral density (BMD, gm/cm2) for the spine was +2.49%, the hip +2.55%, and the forearm -2.46%. Increases in BMD at the spine and hip were not significant and women lost BMD in the forearm; however, without HRT, postmenopausal women are likely to lose bone every year. This intervention may be an effective alternative to HRT for preventing osteoporosis in postmenopausal breast cancer survivors.</td></tr></table>en_GB
dc.date.available2011-10-26T21:12:57Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T21:12:57Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
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