Treatment Time Variable as a Determinant of TRSC-C Symptoms & Severity Among Pediatric Outpatients with Acute Lymphoblastic Leukemia

2.50
Hdl Handle:
http://hdl.handle.net/10755/158901
Type:
Presentation
Title:
Treatment Time Variable as a Determinant of TRSC-C Symptoms & Severity Among Pediatric Outpatients with Acute Lymphoblastic Leukemia
Abstract:
Treatment Time Variable as a Determinant of TRSC-C Symptoms & Severity Among Pediatric Outpatients with Acute Lymphoblastic Leukemia
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2010
Author:Riddle, Ryane, Master's In Science
P.I. Institution Name:University of Kansas
Contact Address:8921 E 81st, Raytown, MO, 64138, USA
Contact Telephone:913-205-9013
Co-Authors:R.M. Riddle, P.D. Williams, School of Nursing, University of Kansas , Kansas City, KS; K. Stegenga, Oncology/Hematology, Children's Mercy Hospital & Clinics, Kansas City, MO; L. Ridder, N. Potter, A.R. Williams, Pediatric Hem/Onc, KU Medical Center, Kansa
Questions: Using the Therapy-Related Symptoms Checklist-Children (TRSC-C): (a) What symptoms are reported most frequently/severely by caregivers/children with leukemia? (b) Are there significant differences in symptom severity between those in early intense treatment 9 months or less from start, n=15 (and those on later, less intense treatment, more than 9 months from start, n=22)? Method: Sample, 37 pediatric oncology outpatients. Instrument, TRSC-C: higher scores, greater symptom frequency/severity. Self-report/parent-report scale, 34 symptoms: severity ratings, "0" [None], "1" [Little bit], "2" [Quite a bit], "3" [A lot], and "4" [Whole lot]; Cronbach's alpha=.89. Secondary data analysis; Fisher's exact tests on each symptom, comparing 2 Time groupings (Question 2); and frequencies/percentages (Question 1). Results: Question 1: 7/34 symptoms reported by 50 plus in "early" group [top 5: feeling sluggish, 80%; taste change, 73%; nausea& vomiting, 67%; loss appetite,60%]. In "later" group, 4/34 symptoms [top 4: nausea 73%, feeling sluggish 68%, irritable 64%, constipation 50%. In "Early" group, severity score Means near "quite a bit" on: taste change, feeling sluggish, nausea, appetite loss, dizzy, hair loss; in "Later" group: feeling sluggish, appetite loss, taste change, constipation. Question 2: Significant differences in severity by Time during treatment on 3 symptoms. "Vomiting" and "Taste change" reported by "Early" group more than "Later" group (p<.02, one-tailed). "Agitation" reported by "Later" group more than "Early" group (p<.03). No symptoms added to list. Conclusions: Pilot study; power low. Larger study may show more significant differences between groups. TRSC-C may be a comprehensive symptom list for oncology patients; helps prioritize symptoms needing intervention, evaluate outcomes.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleTreatment Time Variable as a Determinant of TRSC-C Symptoms & Severity Among Pediatric Outpatients with Acute Lymphoblastic Leukemiaen_GB
dc.identifier.urihttp://hdl.handle.net/10755/158901-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Treatment Time Variable as a Determinant of TRSC-C Symptoms &amp; Severity Among Pediatric Outpatients with Acute Lymphoblastic Leukemia</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2010</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Riddle, Ryane, Master's In Science</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of Kansas</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">8921 E 81st, Raytown, MO, 64138, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">913-205-9013</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">ryanemeredyth@hotmail.com</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">R.M. Riddle, P.D. Williams, School of Nursing, University of Kansas , Kansas City, KS; K. Stegenga, Oncology/Hematology, Children's Mercy Hospital &amp; Clinics, Kansas City, MO; L. Ridder, N. Potter, A.R. Williams, Pediatric Hem/Onc, KU Medical Center, Kansa</td></tr><tr><td colspan="2" class="item-abstract">Questions: Using the Therapy-Related Symptoms Checklist-Children (TRSC-C): (a) What symptoms are reported most frequently/severely by caregivers/children with leukemia? (b) Are there significant differences in symptom severity between those in early intense treatment 9 months or less from start, n=15 (and those on later, less intense treatment, more than 9 months from start, n=22)? Method: Sample, 37 pediatric oncology outpatients. Instrument, TRSC-C: higher scores, greater symptom frequency/severity. Self-report/parent-report scale, 34 symptoms: severity ratings, &quot;0&quot; [None], &quot;1&quot; [Little bit], &quot;2&quot; [Quite a bit], &quot;3&quot; [A lot], and &quot;4&quot; [Whole lot]; Cronbach's alpha=.89. Secondary data analysis; Fisher's exact tests on each symptom, comparing 2 Time groupings (Question 2); and frequencies/percentages (Question 1). Results: Question 1: 7/34 symptoms reported by 50 plus in &quot;early&quot; group [top 5: feeling sluggish, 80%; taste change, 73%; nausea&amp; vomiting, 67%; loss appetite,60%]. In &quot;later&quot; group, 4/34 symptoms [top 4: nausea 73%, feeling sluggish 68%, irritable 64%, constipation 50%. In &quot;Early&quot; group, severity score Means near &quot;quite a bit&quot; on: taste change, feeling sluggish, nausea, appetite loss, dizzy, hair loss; in &quot;Later&quot; group: feeling sluggish, appetite loss, taste change, constipation. Question 2: Significant differences in severity by Time during treatment on 3 symptoms. &quot;Vomiting&quot; and &quot;Taste change&quot; reported by &quot;Early&quot; group more than &quot;Later&quot; group (p&lt;.02, one-tailed). &quot;Agitation&quot; reported by &quot;Later&quot; group more than &quot;Early&quot; group (p&lt;.03). No symptoms added to list. Conclusions: Pilot study; power low. Larger study may show more significant differences between groups. TRSC-C may be a comprehensive symptom list for oncology patients; helps prioritize symptoms needing intervention, evaluate outcomes.</td></tr></table>en_GB
dc.date.available2011-10-26T21:30:27Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T21:30:27Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
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