2.50
Hdl Handle:
http://hdl.handle.net/10755/159540
Type:
Presentation
Title:
Standard and Immune-Enhancing Oral Formulas in HIV-Infected Persons
Abstract:
Standard and Immune-Enhancing Oral Formulas in HIV-Infected Persons
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2002
Author:Keithley, Joyce, DNS/DNSc/DSN
P.I. Institution Name:Rush University
Title:Professor
Contact Address:College of Nursing, 600 South Paulina, Suite 1080, Chicago, IL, 60612-3873, USA
Contact Telephone:312.942.5820
Purpose: The aim of this study was to compare the effects of an immune-enhancing oral formula and a standard oral formula on nutrition and immune measures in asymptomatic HIV-infected persons. A secondary aim was to evaluate the feasibility of maintaining a diverse sample of outpatients on a long-term oral formula protocol. Methods: In this multicenter controlled non-blinded study, 90 asymptomatic HIV-infected persons with CD4 cell counts between 275 and 550 cells/mm3 were randomized to a control group; a standard oral formula group (Ensure Plus(r)[Ross Laboratories, Columbus, Ohio]); or an immune-enhancing oral formula group (Advera(r)[Ross Laboratories, Columbus, Ohio]). All groups received basic nutritional counseling. Participants were evaluated on nutrition, immune, and feasibility measures at three-month intervals during the twelve-month study period. Differences in nutrition and immune measures among the three groups were analyzed using the Kruskal-Wallis and Wilcoxon tests. Wilcoxon tests and correlation coefficients were used to analyze feasibility data. Results: Among the three groups, there were no significant differences with respect to body weight, BIA-derived body cell and fat mass, daily caloric intake, and serum albumin at any of the study visits. Moreover, absolute CD4+ T lymphocytes and percentages did not significantly differ at any time point among the three groups. Acceptability and tolerance of the formulas were high for both the standard and immune-enhancing oral formula groups. Conclusions: Within the context and limitations of this study, standard and immune-enhancing oral formulas consumed daily for a year had no differential effects on nutrition or immune parameters in asymptomatic HIV-infected persons. Long-term treatment with nutritional supplements is feasible in diverse and predominantly low-income HIV-infected individuals.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleStandard and Immune-Enhancing Oral Formulas in HIV-Infected Personsen_GB
dc.identifier.urihttp://hdl.handle.net/10755/159540-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Standard and Immune-Enhancing Oral Formulas in HIV-Infected Persons</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2002</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Keithley, Joyce, DNS/DNSc/DSN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Rush University</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Professor</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">College of Nursing, 600 South Paulina, Suite 1080, Chicago, IL, 60612-3873, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">312.942.5820</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">jkeithley@rushu.rush.edu</td></tr><tr><td colspan="2" class="item-abstract">Purpose: The aim of this study was to compare the effects of an immune-enhancing oral formula and a standard oral formula on nutrition and immune measures in asymptomatic HIV-infected persons. A secondary aim was to evaluate the feasibility of maintaining a diverse sample of outpatients on a long-term oral formula protocol. Methods: In this multicenter controlled non-blinded study, 90 asymptomatic HIV-infected persons with CD4 cell counts between 275 and 550 cells/mm3 were randomized to a control group; a standard oral formula group (Ensure Plus(r)[Ross Laboratories, Columbus, Ohio]); or an immune-enhancing oral formula group (Advera(r)[Ross Laboratories, Columbus, Ohio]). All groups received basic nutritional counseling. Participants were evaluated on nutrition, immune, and feasibility measures at three-month intervals during the twelve-month study period. Differences in nutrition and immune measures among the three groups were analyzed using the Kruskal-Wallis and Wilcoxon tests. Wilcoxon tests and correlation coefficients were used to analyze feasibility data. Results: Among the three groups, there were no significant differences with respect to body weight, BIA-derived body cell and fat mass, daily caloric intake, and serum albumin at any of the study visits. Moreover, absolute CD4+ T lymphocytes and percentages did not significantly differ at any time point among the three groups. Acceptability and tolerance of the formulas were high for both the standard and immune-enhancing oral formula groups. Conclusions: Within the context and limitations of this study, standard and immune-enhancing oral formulas consumed daily for a year had no differential effects on nutrition or immune parameters in asymptomatic HIV-infected persons. Long-term treatment with nutritional supplements is feasible in diverse and predominantly low-income HIV-infected individuals.</td></tr></table>en_GB
dc.date.available2011-10-26T22:06:32Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T22:06:32Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
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