2.50
Hdl Handle:
http://hdl.handle.net/10755/159963
Type:
Presentation
Title:
Effect of Cognitive Impairment on Quality of Life among Breast Cancer Survivors
Abstract:
Effect of Cognitive Impairment on Quality of Life among Breast Cancer Survivors
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2010
Author:Von Ah, Diane, PhD
P.I. Institution Name:Indiana University
Contact Address:1111 Middle Drive, Indianapolis, IN, 46202, USA
Contact Telephone:317-278-2827
Co-Authors:D. Von Ah, V. Champion, School of Nursing, Indiana University, Indianapolis, IN; L. Moser, F. Unverzagt, Department of Psychiatry, Indiana University, Indianapolis, IN; P. Monahan , Q. Zhoa, Department of Medicine, Indiana University, Indianapolis, IN;
Objective: Research has documented significant cognitive impairment among women treated for breast cancer, yet little is known about its impact on quality of life. Therefore, the purpose of this study was to examine the impact of cognitive impairment on psychological (depressive symptoms, overall well-being, perceived stress and personal growth) and physical well-being (physical functioning and fatigue) of breast cancer survivors compared to a healthy control group. Methods: 444 breast cancer survivors who were 3 to 8 years post-chemotherapy treatment and 355 healthy women completed a one-time neuropsychological assessment. Cognitive impairment was defined as scoring 1.5 standard deviations (SD) below the mean of the control group on a test. An overall composite impairment score was also calculated for each individual survivor as the average of the standard Z scores over all five cognitive tests. Impairment on the standardized composite score was again defined as a standardized score less than 1.5 SD below the healthy control mean. Linear regression models were used controlling for age, education, and income. Results: Small percentages of breast cancer survivors (< 12% across all tests) evidenced deficits in memory (immediate recall and delayed recall), cognitive processing speed, attention, and verbal fluency. However, breast cancer survivors who were identified as having overall cognitive impairment had both significantly greater perceived stress and less personal growth. Specifically, those survivors who had deficits in attention had greater stress and breast cancer survivors who had memory problems (poorer immediate recall) experienced significantly less personal growth. Conclusion: Cognitive impairment may be subtle yet have significant impact on psychological well-being among breast cancer survivors. Further research is needed to validate these potential relationships, which suggest that cognitive impairment among breast cancer survivors may warrant intervention.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleEffect of Cognitive Impairment on Quality of Life among Breast Cancer Survivorsen_GB
dc.identifier.urihttp://hdl.handle.net/10755/159963-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Effect of Cognitive Impairment on Quality of Life among Breast Cancer Survivors</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2010</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Von Ah, Diane, PhD</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Indiana University</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">1111 Middle Drive, Indianapolis, IN, 46202, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">317-278-2827</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">dvonah@iupui.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">D. Von Ah, V. Champion, School of Nursing, Indiana University, Indianapolis, IN; L. Moser, F. Unverzagt, Department of Psychiatry, Indiana University, Indianapolis, IN; P. Monahan , Q. Zhoa, Department of Medicine, Indiana University, Indianapolis, IN;</td></tr><tr><td colspan="2" class="item-abstract">Objective: Research has documented significant cognitive impairment among women treated for breast cancer, yet little is known about its impact on quality of life. Therefore, the purpose of this study was to examine the impact of cognitive impairment on psychological (depressive symptoms, overall well-being, perceived stress and personal growth) and physical well-being (physical functioning and fatigue) of breast cancer survivors compared to a healthy control group. Methods: 444 breast cancer survivors who were 3 to 8 years post-chemotherapy treatment and 355 healthy women completed a one-time neuropsychological assessment. Cognitive impairment was defined as scoring 1.5 standard deviations (SD) below the mean of the control group on a test. An overall composite impairment score was also calculated for each individual survivor as the average of the standard Z scores over all five cognitive tests. Impairment on the standardized composite score was again defined as a standardized score less than 1.5 SD below the healthy control mean. Linear regression models were used controlling for age, education, and income. Results: Small percentages of breast cancer survivors (&lt; 12% across all tests) evidenced deficits in memory (immediate recall and delayed recall), cognitive processing speed, attention, and verbal fluency. However, breast cancer survivors who were identified as having overall cognitive impairment had both significantly greater perceived stress and less personal growth. Specifically, those survivors who had deficits in attention had greater stress and breast cancer survivors who had memory problems (poorer immediate recall) experienced significantly less personal growth. Conclusion: Cognitive impairment may be subtle yet have significant impact on psychological well-being among breast cancer survivors. Further research is needed to validate these potential relationships, which suggest that cognitive impairment among breast cancer survivors may warrant intervention.</td></tr></table>en_GB
dc.date.available2011-10-26T22:29:52Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T22:29:52Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
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