Recruitment and Early Retention of Women with Advanced Breast Cancer in a Complementary and Alternative Medicine (CAM) Trial

2.50
Hdl Handle:
http://hdl.handle.net/10755/159974
Type:
Presentation
Title:
Recruitment and Early Retention of Women with Advanced Breast Cancer in a Complementary and Alternative Medicine (CAM) Trial
Abstract:
Recruitment and Early Retention of Women with Advanced Breast Cancer in a Complementary and Alternative Medicine (CAM) Trial
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2009
Author:Adams, Lora, MSN
P.I. Institution Name:Michigan State University
Title:College of Nursing
Contact Address:E515 West Fee Hall, East Lansing, MI, 48824, USA
Contact Telephone:5178622388
Co-Authors:L. Adams, G.K. Wyatt, A. Siddiqi, College of Nursing, Michigan State University, East Lansing, MI; A. Sikorskii, Department of Statistics and Probability, Michigan State University, East Lansing, MI;
Purpose: 1) Assess reasons for refusal to participate and for dropping out before intake interview from an ongoing CAM trial of reflexology; and 2) Investigate the utility of demographics, disease characteristics, and Palliative Prognostic Score (PPS) as predictors of early dropout from the trial following consent. Conceptual Framework: The Wyatt Quality of Life Model provides the conceptual framework for the CAM trial. Subjects: Eligible women had a diagnosis of advanced breast cancer, were on chemotherapy, and had a PPS of 11 or less (i.e., a 30 day survival probability of less than or equal to 70%). Methods: Eligible women (N=326) were approached at 12 Midwestern cancer centers. Refusal reasons were obtained for N=91 women. Twenty-five women dropped out before the intake interview; 210 completed the intake interview. Medical records data included demographics, cancer recurrence and metastasis, and the PPS. Differences between groups were using t-tests and Fisher's exact tests. Results: Fewer than 10% of the women who refused to participate gave the reasons of being "too sick" or "overwhelmed". "Disinterest in research," was the most frequent refusal reason. Among 25 early dropouts, 28% were Black women as compared to 9.7% of Black women among those who completed the intake interview (p=.03). Among early dropouts, 64% had metastasis; among those who completed the intake interview, 73.9% had metastasis (p=.10). Cancer recurrence, age, and the PPS were not predictive of early retention. Conclusions: Women with advanced disease were likely to enter and remain in the trial despite deteriorating health. Using the PPS as part of inclusion criteria was not effective in improving retention. Acknowledgement of Funding: NCI 1RO1CA104883-01A1
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleRecruitment and Early Retention of Women with Advanced Breast Cancer in a Complementary and Alternative Medicine (CAM) Trialen_GB
dc.identifier.urihttp://hdl.handle.net/10755/159974-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Recruitment and Early Retention of Women with Advanced Breast Cancer in a Complementary and Alternative Medicine (CAM) Trial</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2009</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Adams, Lora, MSN</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Michigan State University</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">College of Nursing</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">E515 West Fee Hall, East Lansing, MI, 48824, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">5178622388</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">adamslo1@msu.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">L. Adams, G.K. Wyatt, A. Siddiqi, College of Nursing, Michigan State University, East Lansing, MI; A. Sikorskii, Department of Statistics and Probability, Michigan State University, East Lansing, MI;</td></tr><tr><td colspan="2" class="item-abstract">Purpose: 1) Assess reasons for refusal to participate and for dropping out before intake interview from an ongoing CAM trial of reflexology; and 2) Investigate the utility of demographics, disease characteristics, and Palliative Prognostic Score (PPS) as predictors of early dropout from the trial following consent. Conceptual Framework: The Wyatt Quality of Life Model provides the conceptual framework for the CAM trial. Subjects: Eligible women had a diagnosis of advanced breast cancer, were on chemotherapy, and had a PPS of 11 or less (i.e., a 30 day survival probability of less than or equal to 70%). Methods: Eligible women (N=326) were approached at 12 Midwestern cancer centers. Refusal reasons were obtained for N=91 women. Twenty-five women dropped out before the intake interview; 210 completed the intake interview. Medical records data included demographics, cancer recurrence and metastasis, and the PPS. Differences between groups were using t-tests and Fisher's exact tests. Results: Fewer than 10% of the women who refused to participate gave the reasons of being &quot;too sick&quot; or &quot;overwhelmed&quot;. &quot;Disinterest in research,&quot; was the most frequent refusal reason. Among 25 early dropouts, 28% were Black women as compared to 9.7% of Black women among those who completed the intake interview (p=.03). Among early dropouts, 64% had metastasis; among those who completed the intake interview, 73.9% had metastasis (p=.10). Cancer recurrence, age, and the PPS were not predictive of early retention. Conclusions: Women with advanced disease were likely to enter and remain in the trial despite deteriorating health. Using the PPS as part of inclusion criteria was not effective in improving retention. Acknowledgement of Funding: NCI 1RO1CA104883-01A1</td></tr></table>en_GB
dc.date.available2011-10-26T22:30:29Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T22:30:29Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
All Items in this repository are protected by copyright, with all rights reserved, unless otherwise indicated.