2.50
Hdl Handle:
http://hdl.handle.net/10755/160081
Type:
Presentation
Title:
Quantitative Ultrasound Predicts Cervical Ripening in the Rat
Abstract:
Quantitative Ultrasound Predicts Cervical Ripening in the Rat
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2006
Author:McFarlin, Barbara, PhD, CNM
P.I. Institution Name:University of Illinois at Chicago
Title:Assistant Professor
Contact Address:Maternal Child Nursing, 845 S. Damen Ave, Chicago, IL, 61801, USA
Contact Telephone:312-996-0516
Co-Authors:William D. O'Brien, PhD, Professor; Michael L. Oelze, PhD, Assistant Professor; Zachary F. James, PhD, Professor; and Rosemary White-Traut, DNSc, Associate Professor
The incidence of preterm birth has risen 16% since 1990. Prevention programs have focused on controlling uterine contractions rather than cervical ripening, which precedes labor. The purpose of this study was to test a new ultrasound methodology to quantify cervical ripening. The cervices of 13 non-pregnant and 65 timed-pregnant (pregnancy days 15, 17, 19, 20 & 21) Sprague-Dawley rats were scanned with a 70-MHz transducer. Ultrasound scattering from the cervices was quantified [scatterer diameter (SD), scatterer acoustic concentration (AC )and scatterer strength factor (SSF)] and compared to hydroxyproline and water content. Significant differences were observed between the groups in: SD, F(5,72)=10.7; AC, F(5,72)=19.5 and SSF, F(5,72)=26.5, p<.0001. Percentage of hydroxyproline decreased from non-pregnant group to the day 21 of pregnancy, F(5,72)=107.5, p<.0001. Hydroxyproline per cervix significantly correlated with gestational age group, SD, AC and SSF. Given the ultrasound variables of SD, AC and SSF, discriminant analysis significantly classified gestational group assignment. Quantitative ultrasound detected cervical ripening in the rat.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleQuantitative Ultrasound Predicts Cervical Ripening in the Raten_GB
dc.identifier.urihttp://hdl.handle.net/10755/160081-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Quantitative Ultrasound Predicts Cervical Ripening in the Rat</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2006</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">McFarlin, Barbara, PhD, CNM</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">University of Illinois at Chicago</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Assistant Professor</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">Maternal Child Nursing, 845 S. Damen Ave, Chicago, IL, 61801, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">312-996-0516</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">bmcfar1@uic.edu</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">William D. O'Brien, PhD, Professor; Michael L. Oelze, PhD, Assistant Professor; Zachary F. James, PhD, Professor; and Rosemary White-Traut, DNSc, Associate Professor</td></tr><tr><td colspan="2" class="item-abstract">The incidence of preterm birth has risen 16% since 1990. Prevention programs have focused on controlling uterine contractions rather than cervical ripening, which precedes labor. The purpose of this study was to test a new ultrasound methodology to quantify cervical ripening. The cervices of 13 non-pregnant and 65 timed-pregnant (pregnancy days 15, 17, 19, 20 &amp; 21) Sprague-Dawley rats were scanned with a 70-MHz transducer. Ultrasound scattering from the cervices was quantified [scatterer diameter (SD), scatterer acoustic concentration (AC )and scatterer strength factor (SSF)] and compared to hydroxyproline and water content. Significant differences were observed between the groups in: SD, F(5,72)=10.7; AC, F(5,72)=19.5 and SSF, F(5,72)=26.5, p&lt;.0001. Percentage of hydroxyproline decreased from non-pregnant group to the day 21 of pregnancy, F(5,72)=107.5, p&lt;.0001. Hydroxyproline per cervix significantly correlated with gestational age group, SD, AC and SSF. Given the ultrasound variables of SD, AC and SSF, discriminant analysis significantly classified gestational group assignment. Quantitative ultrasound detected cervical ripening in the rat.</td></tr></table>en_GB
dc.date.available2011-10-26T22:36:30Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T22:36:30Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
All Items in this repository are protected by copyright, with all rights reserved, unless otherwise indicated.