2.50
Hdl Handle:
http://hdl.handle.net/10755/160667
Type:
Presentation
Title:
Detection of pulmonary aspiration using pulse oximetry
Abstract:
Detection of pulmonary aspiration using pulse oximetry
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2001
Author:Edwards, Sharon
P.I. Institution Name:Saint Louis University
Contact Address:School of Nursing, 3525 Caroline Street, St. Louis, MO, 63104, USA
Contact Telephone:314.577.8930
The proposed research study was designed to investigate the ability of pulse oximetry (based on the principles of plethysmography and spectrophotometry) to detect small-volume aspiration in a mechanically ventilated animal model. A sample of 24 experimental animals (rabbits) will undergo 3 forced intra-tracheal micro-aspirations of a 1:1 mixture of human gastric fluid and enteral formula during a 6-hour period. An additional 6 control animals will receive a 0.9% normal saline intra-tracheal instillation. Further, the presence of fiber in the enteral formula is likely to increase the degree of lung injury. Therefore, two types of formula (fiber-free and fiber-containing) will be investigated. During the experiment, pulse oximetry measurements will be recorded every 15 minutes. In accordance with previous pulse oximetry studies, detection of pulmonary aspiration will be operationally defined as a decrease in SpO2 greater than or equal to three percent. The data will be analyzed with several planned comparisons. A 2 x 3 x 8 repeated measures analysis of covariance will be done to determine the interaction between the presence/absence of fiber, period of infusion of micro-aspirate, and time of observation. This data will be analyzed with additional data gathered in the parent study (detecting aspiration associated with tube-feedings).
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleDetection of pulmonary aspiration using pulse oximetryen_GB
dc.identifier.urihttp://hdl.handle.net/10755/160667-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Detection of pulmonary aspiration using pulse oximetry</td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2001</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Edwards, Sharon</td></tr><tr class="item-institute"><td class="label">P.I. Institution Name:</td><td class="value">Saint Louis University</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">School of Nursing, 3525 Caroline Street, St. Louis, MO, 63104, USA</td></tr><tr class="item-phone"><td class="label">Contact Telephone:</td><td class="value">314.577.8930</td></tr><tr class="item-email"><td class="label">Email:</td><td class="value">edwards@slu.edu</td></tr><tr><td colspan="2" class="item-abstract">The proposed research study was designed to investigate the ability of pulse oximetry (based on the principles of plethysmography and spectrophotometry) to detect small-volume aspiration in a mechanically ventilated animal model. A sample of 24 experimental animals (rabbits) will undergo 3 forced intra-tracheal micro-aspirations of a 1:1 mixture of human gastric fluid and enteral formula during a 6-hour period. An additional 6 control animals will receive a 0.9% normal saline intra-tracheal instillation. Further, the presence of fiber in the enteral formula is likely to increase the degree of lung injury. Therefore, two types of formula (fiber-free and fiber-containing) will be investigated. During the experiment, pulse oximetry measurements will be recorded every 15 minutes. In accordance with previous pulse oximetry studies, detection of pulmonary aspiration will be operationally defined as a decrease in SpO2 greater than or equal to three percent. The data will be analyzed with several planned comparisons. A 2 x 3 x 8 repeated measures analysis of covariance will be done to determine the interaction between the presence/absence of fiber, period of infusion of micro-aspirate, and time of observation. This data will be analyzed with additional data gathered in the parent study (detecting aspiration associated with tube-feedings).</td></tr></table>en_GB
dc.date.available2011-10-26T23:08:43Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T23:08:43Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
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