2.50
Hdl Handle:
http://hdl.handle.net/10755/161312
Type:
Presentation
Title:
Effects of exercise on the fatigue of Myasthenia gravis
Abstract:
Effects of exercise on the fatigue of Myasthenia gravis
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2004
Author:Grohar-Murray, Mary, PhD, RN
Title:Associate Professor
Contact Address:SON, 3525 Caroline Mall, St. Louis, MO, 63104-1099 , USA
Co-Authors:Ethel Frese, Associate Professor; Becky Jo Parks, MD, Professor
Myasthenia Gravis (MG), a neuromuscular disease, is characterized by extreme fatigue. Exercise produces fatigue resistance in non-neuromuscular and in some neuromuscular clinical conditions (Vignosis, 1983, Florence and Hagberg, 1984, Wright et al., 1996). The purpose of this study was to evaluate the effect of a mild sustained exercise program on the fatigue of patients with Myasthenia Gravis. Eleven Participants were randomized into control or treatment groups and subjected to the following measures (1) a pre-exercise assessment including maximal inspiratory and expiratory pressures, (2) a self-report demographic sheet with history of MG status; (3) Leidy Functional Status Survey; (4) the Myasthenia Gravis Fatigue Scale; (5) dynamometer readings on dominant hand; (6) the "six minute walk test" and requested to (7) maintain a daily activity diary. Participants in the treatment group engaged in a home based walking program. At six weeks and upon completion of the study the same set of measures (1) through (6) were repeated and the activity logs from both groups were collected (at completion). Data analysis, using SPSS, compared pre and post measures between groups and within subjects. Results revealed the treatment group increased endurance (T test, p .02) as measured by the cycles walked with the six-minute walk test. There were no other significant relationships found on the other variables. Anecdotally, it was revealed the treatment group was also exercising. Fatigue scores and Functional Status scores within or between subjects were not significant but improvement was reported. This study provides evidence that a mid exercise program among stable MG patients is safe and effective in increasing endurance. Further study with a larger group including aerobic and strengthening exercises is indicated to evaluate whether sustained systematic exercise reduces fatigue encountered by MG patient.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleEffects of exercise on the fatigue of Myasthenia gravisen_GB
dc.identifier.urihttp://hdl.handle.net/10755/161312-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Effects of exercise on the fatigue of Myasthenia gravis </td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2004</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Grohar-Murray, Mary, PhD, RN</td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Associate Professor</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">SON, 3525 Caroline Mall, St. Louis, MO, 63104-1099 , USA</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Ethel Frese, Associate Professor; Becky Jo Parks, MD, Professor</td></tr><tr><td colspan="2" class="item-abstract">Myasthenia Gravis (MG), a neuromuscular disease, is characterized by extreme fatigue. Exercise produces fatigue resistance in non-neuromuscular and in some neuromuscular clinical conditions (Vignosis, 1983, Florence and Hagberg, 1984, Wright et al., 1996). The purpose of this study was to evaluate the effect of a mild sustained exercise program on the fatigue of patients with Myasthenia Gravis. Eleven Participants were randomized into control or treatment groups and subjected to the following measures (1) a pre-exercise assessment including maximal inspiratory and expiratory pressures, (2) a self-report demographic sheet with history of MG status; (3) Leidy Functional Status Survey; (4) the Myasthenia Gravis Fatigue Scale; (5) dynamometer readings on dominant hand; (6) the &quot;six minute walk test&quot; and requested to (7) maintain a daily activity diary. Participants in the treatment group engaged in a home based walking program. At six weeks and upon completion of the study the same set of measures (1) through (6) were repeated and the activity logs from both groups were collected (at completion). Data analysis, using SPSS, compared pre and post measures between groups and within subjects. Results revealed the treatment group increased endurance (T test, p .02) as measured by the cycles walked with the six-minute walk test. There were no other significant relationships found on the other variables. Anecdotally, it was revealed the treatment group was also exercising. Fatigue scores and Functional Status scores within or between subjects were not significant but improvement was reported. This study provides evidence that a mid exercise program among stable MG patients is safe and effective in increasing endurance. Further study with a larger group including aerobic and strengthening exercises is indicated to evaluate whether sustained systematic exercise reduces fatigue encountered by MG patient.</td></tr></table>en_GB
dc.date.available2011-10-26T23:19:21Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T23:19:21Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
All Items in this repository are protected by copyright, with all rights reserved, unless otherwise indicated.