Fatigue and Physical Activity Before and Immediately After Stem Cell Transplantation

2.50
Hdl Handle:
http://hdl.handle.net/10755/161313
Type:
Presentation
Title:
Fatigue and Physical Activity Before and Immediately After Stem Cell Transplantation
Abstract:
Fatigue and Physical Activity Before and Immediately After Stem Cell Transplantation
Conference Sponsor:Midwest Nursing Research Society
Conference Year:2004
Author:Hacker, Eileen, PhD, RN, AOCN
Title:Clinical Assistant Professor
Contact Address:CON, 845 S. Damen (M/C 802), Chicago, IL, 60612, USA
Co-Authors:Carol Ferrans, PhD, RN, FAAN, Professor, College of Nursing; Ellen Verlen, BSN, RN, Graduate Student; Farhad Ravandi, MD; Koen Van Besein, MD
Stem cell transplantation (SCT) impacts many aspects of a patient's life, particularly during the acute post-transplant period. Problems, such as fatigue and decreased physical activity, may result in long-term consequences and diminished quality of life (QOL). This study examined fatigue, physical activity, health status, and QOL immediately following SCT. A secondary purpose was to examine the feasibility of using wrist actigraphy as a patient tolerable means for obtaining fatigue and physical activity data. Conceptual Framework: Wilson and Cleary’s Conceptual Model of Patient Outcomes guided the study. Subjects: The convenience sample (n=20) included allogeneic and autologous transplant patient drawn from two academic medical centers. Methods: This feasibility study used a prospective, repeated measure design. Subjects were assessed over a five-day period before and after the transplant. Subjects wore a wrist actigraph to measure physical activity. They rated fatigue intensity three times daily. At the end of both five-day periods, subjects completed measures of perceived health status (EORTC QLQ C-30) and life satisfaction (QLI). Descriptive statistics, paired t-tests, and one-way repeated measures ANOVA were used to analyze the data. Results: Study results indicate that physical activity significantly declined following SCT (p<0.001). This decline coincided with diminished physical (p<0.05), emotional (p<0.01), role (p<0.01), and cognitive (p<0.05) functioning. Symptoms experienced increased during the acute post transplant period (fatigue, p<0.001; pain, p<0.001; nausea/vomiting, p<0.001; sleep disturbances, p<0.01; appetite loss, p<0.001; and diarrhea, p<0.001). Quality of life was significantly worse (p<0.005). Conclusions: Findings suggest that SCT patients experience reduced physical activity, diminished functioning, increased symptoms and poorer QOL during the acute post-transplant period. Findings demonstrate that it is feasible to obtain fatigue, physical activity, health status and QOL information if the patient burden is reasonable. This information can be used to develop interventions that alleviate symptoms, increase physical activity, improve health status and QOL.
Repository Posting Date:
26-Oct-2011
Date of Publication:
17-Oct-2011
Sponsors:
Midwest Nursing Research Society

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleFatigue and Physical Activity Before and Immediately After Stem Cell Transplantationen_GB
dc.identifier.urihttp://hdl.handle.net/10755/161313-
dc.description.abstract<table><tr><td colspan="2" class="item-title">Fatigue and Physical Activity Before and Immediately After Stem Cell Transplantation </td></tr><tr class="item-sponsor"><td class="label">Conference Sponsor:</td><td class="value">Midwest Nursing Research Society</td></tr><tr class="item-year"><td class="label">Conference Year:</td><td class="value">2004</td></tr><tr class="item-author"><td class="label">Author:</td><td class="value">Hacker, Eileen, PhD, RN, AOCN </td></tr><tr class="item-author-title"><td class="label">Title:</td><td class="value">Clinical Assistant Professor</td></tr><tr class="item-address"><td class="label">Contact Address:</td><td class="value">CON, 845 S. Damen (M/C 802), Chicago, IL, 60612, USA</td></tr><tr class="item-co-authors"><td class="label">Co-Authors:</td><td class="value">Carol Ferrans, PhD, RN, FAAN, Professor, College of Nursing; Ellen Verlen, BSN, RN, Graduate Student; Farhad Ravandi, MD; Koen Van Besein, MD </td></tr><tr><td colspan="2" class="item-abstract">Stem cell transplantation (SCT) impacts many aspects of a patient's life, particularly during the acute post-transplant period. Problems, such as fatigue and decreased physical activity, may result in long-term consequences and diminished quality of life (QOL). This study examined fatigue, physical activity, health status, and QOL immediately following SCT. A secondary purpose was to examine the feasibility of using wrist actigraphy as a patient tolerable means for obtaining fatigue and physical activity data. Conceptual Framework: Wilson and Cleary&rsquo;s Conceptual Model of Patient Outcomes guided the study. Subjects: The convenience sample (n=20) included allogeneic and autologous transplant patient drawn from two academic medical centers. Methods: This feasibility study used a prospective, repeated measure design. Subjects were assessed over a five-day period before and after the transplant. Subjects wore a wrist actigraph to measure physical activity. They rated fatigue intensity three times daily. At the end of both five-day periods, subjects completed measures of perceived health status (EORTC QLQ C-30) and life satisfaction (QLI). Descriptive statistics, paired t-tests, and one-way repeated measures ANOVA were used to analyze the data. Results: Study results indicate that physical activity significantly declined following SCT (p&lt;0.001). This decline coincided with diminished physical (p&lt;0.05), emotional (p&lt;0.01), role (p&lt;0.01), and cognitive (p&lt;0.05) functioning. Symptoms experienced increased during the acute post transplant period (fatigue, p&lt;0.001; pain, p&lt;0.001; nausea/vomiting, p&lt;0.001; sleep disturbances, p&lt;0.01; appetite loss, p&lt;0.001; and diarrhea, p&lt;0.001). Quality of life was significantly worse (p&lt;0.005). Conclusions: Findings suggest that SCT patients experience reduced physical activity, diminished functioning, increased symptoms and poorer QOL during the acute post-transplant period. Findings demonstrate that it is feasible to obtain fatigue, physical activity, health status and QOL information if the patient burden is reasonable. This information can be used to develop interventions that alleviate symptoms, increase physical activity, improve health status and QOL.</td></tr></table>en_GB
dc.date.available2011-10-26T23:19:22Z-
dc.date.issued2011-10-17en_GB
dc.date.accessioned2011-10-26T23:19:22Z-
dc.description.sponsorshipMidwest Nursing Research Societyen_GB
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