2.50
Hdl Handle:
http://hdl.handle.net/10755/161795
Category:
Abstract
Type:
Presentation
Title:
Isolated Limb Infusion: Alternate to Isolated Limb Perfusion
Author(s):
Simon, Margaret O.
Author Details:
Margaret O. Simon, RN, CNOR, Memorial Sloan Kettering Cancer Center, New York, New York, USA, email: simonm@mskcc.org
Abstract:
Poster presented at AORN's 58th Annual Congress: Isolated limb perfusion (ILP) using cytotoxic agents is a complex treatment modality to treat recurrent melanoma of an extremity. In our institution, we have instituted a simpler approach: Isolated Limb Infusion (ILI). In this procedure, cytotoxic agents are delivered to the extremity via catheters without systemic side effects. This unique method offers a limb-sparing option for patients who have unresectable tumors of their extremities, who previously were candidates for amputation. The room is warmed to 74 degrees F through induction. In addition, three forced air warming devices are used to maintain body temperature of 38 degrees C. Minimal supplies are required: 60cc syringes, web roll, kerlix, marking pen, temperature probes, needle driver, mayo scissor, and an extra large sheet. Cytotoxic agents are ordered in advance and delivered just in time to insure potency. Papaverine is obtained from the OR pharmacy. Both the artery and vein catheters are inserted and secured in radiology. Before infusion of the chemotherapeutic agent, complete vascular isolation of the limb is achieved. Once the proximal tourniquet is inflated, papaverine is introduced to the limb, then a normothermic, low flow, hypoxic infusion of melphalan and dactinomycin is circulated through the involved limb. postoperatively, the patient remains on bed rest with the effective limb elevated on pillows to reduce swelling. Vital signs, pedal pulses, pain level, skin integrity, and neurovascular status are monitored. The average length of stay is five days. A partial or complete response was achieved in 85% of patients.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2011
Conference Name:
AORN 58th Annual Congress
Conference Host:
Association of periOperative Registered Nurses
Conference Location:
Philadelphia, Pennsylvania, USA
Description:
AORN 58th Annual Congress, 2011 held March 18, 2011 - March 24, 2011 in Philadelphia Convention Center
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleIsolated Limb Infusion: Alternate to Isolated Limb Perfusionen_GB
dc.contributor.authorSimon, Margaret O.en_US
dc.author.detailsMargaret O. Simon, RN, CNOR, Memorial Sloan Kettering Cancer Center, New York, New York, USA, email: simonm@mskcc.orgen_US
dc.identifier.urihttp://hdl.handle.net/10755/161795-
dc.description.abstractPoster presented at AORN's 58th Annual Congress: Isolated limb perfusion (ILP) using cytotoxic agents is a complex treatment modality to treat recurrent melanoma of an extremity. In our institution, we have instituted a simpler approach: Isolated Limb Infusion (ILI). In this procedure, cytotoxic agents are delivered to the extremity via catheters without systemic side effects. This unique method offers a limb-sparing option for patients who have unresectable tumors of their extremities, who previously were candidates for amputation. The room is warmed to 74 degrees F through induction. In addition, three forced air warming devices are used to maintain body temperature of 38 degrees C. Minimal supplies are required: 60cc syringes, web roll, kerlix, marking pen, temperature probes, needle driver, mayo scissor, and an extra large sheet. Cytotoxic agents are ordered in advance and delivered just in time to insure potency. Papaverine is obtained from the OR pharmacy. Both the artery and vein catheters are inserted and secured in radiology. Before infusion of the chemotherapeutic agent, complete vascular isolation of the limb is achieved. Once the proximal tourniquet is inflated, papaverine is introduced to the limb, then a normothermic, low flow, hypoxic infusion of melphalan and dactinomycin is circulated through the involved limb. postoperatively, the patient remains on bed rest with the effective limb elevated on pillows to reduce swelling. Vital signs, pedal pulses, pain level, skin integrity, and neurovascular status are monitored. The average length of stay is five days. A partial or complete response was achieved in 85% of patients.en_GB
dc.date.available2011-10-27T08:40:43Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T08:40:43Z-
dc.conference.date2011en_US
dc.conference.nameAORN 58th Annual Congressen_US
dc.conference.hostAssociation of periOperative Registered Nursesen_US
dc.conference.locationPhiladelphia, Pennsylvania, USAen_US
dc.descriptionAORN 58th Annual Congress, 2011 held March 18, 2011 - March 24, 2011 in Philadelphia Convention Centeren_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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