The Influence of Enteral Feeding Regimens on Necrotizing Enterocolitis in Preterm Infants

2.50
Hdl Handle:
http://hdl.handle.net/10755/162124
Category:
Abstract
Type:
Presentation
Title:
The Influence of Enteral Feeding Regimens on Necrotizing Enterocolitis in Preterm Infants
Author(s):
Gregory, Katherine E.
Author Details:
Katherine E. Gregory, RN, PhD, Boston College, Chestnut Hill, Massachusetts, USA, email: katherine.gregory.2@bc.edu
Abstract:
Purpose: The purpose of this study is to explain how factors related to enteral feeding regimens play a role in the pathogenesis of necrotizing enterocolitis (NEC) in preterm infants. The research aims to guide multidisciplinary neonatal intensive care teams seeking to decrease the incidence of NEC and enhance preterm infant growth and development through the implementation of improved enteral feeding regimens. Theoretical Framework: The findings of this study are informed by a critical care nursing perspective, which is grounded in the knowledge of physiologic homeostasis and structural integrity. This framework considers the integrated nature of bio-demographic variables, physiologic factors, and clinical interventions that characterize the preterm infant population. Methods (Design, Sample, Setting, Measures, Analysis): This retrospective, predictive case controlled study used data collected from the medical records of 241 preterm infants born at New England Medical Center during 1997-2003. In this matched sample, multivariate analysis techniques were used to differentiate preterm infants who developed NEC from those who did not develop NEC based on six enteral feeding factors. Results: Logistic regression indicated that four enteral feeding factors were significant in predicting NEC. The odds of NEC were 2.5 times greater in preterm infants who received enteral feedings in the first 48 hours of life (p=.004), 2.9 times greater when the enteral feeding regimen was advanced (> 20)ml/kg/day (p=.014), and 5.4 and 3.3 times greater in infants who were not fed nutritionally fortified breast milk (p=.000) or infant formula (p=.001), respectively. Conclusions and Implications: The results of this study emphasize the role that specific factors related to enteral feeding regimens play in the pathogenesis of neonatal comorbidities such as NEC. This sample of preterm infants was less likely to develop NEC after progressing to a point at which enteral feedings were nutritionally fortified. Thus, these findings highlight the need to focus future research on identifying the time at which NEC ensues along the enteral feeding regimen.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2007
Conference Name:
19th Annual Scientific Sessions
Conference Host:
Eastern Nursing Research Society
Conference Location:
Providence, Rhode Island, USA
Description:
Conference theme: Building Communities of Scholarship and Research, held April 12-14, 2007 at The Westin Providence.
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleThe Influence of Enteral Feeding Regimens on Necrotizing Enterocolitis in Preterm Infantsen_GB
dc.contributor.authorGregory, Katherine E.en_US
dc.author.detailsKatherine E. Gregory, RN, PhD, Boston College, Chestnut Hill, Massachusetts, USA, email: katherine.gregory.2@bc.eduen_US
dc.identifier.urihttp://hdl.handle.net/10755/162124-
dc.description.abstractPurpose: The purpose of this study is to explain how factors related to enteral feeding regimens play a role in the pathogenesis of necrotizing enterocolitis (NEC) in preterm infants. The research aims to guide multidisciplinary neonatal intensive care teams seeking to decrease the incidence of NEC and enhance preterm infant growth and development through the implementation of improved enteral feeding regimens. Theoretical Framework: The findings of this study are informed by a critical care nursing perspective, which is grounded in the knowledge of physiologic homeostasis and structural integrity. This framework considers the integrated nature of bio-demographic variables, physiologic factors, and clinical interventions that characterize the preterm infant population. Methods (Design, Sample, Setting, Measures, Analysis): This retrospective, predictive case controlled study used data collected from the medical records of 241 preterm infants born at New England Medical Center during 1997-2003. In this matched sample, multivariate analysis techniques were used to differentiate preterm infants who developed NEC from those who did not develop NEC based on six enteral feeding factors. Results: Logistic regression indicated that four enteral feeding factors were significant in predicting NEC. The odds of NEC were 2.5 times greater in preterm infants who received enteral feedings in the first 48 hours of life (p=.004), 2.9 times greater when the enteral feeding regimen was advanced (> 20)ml/kg/day (p=.014), and 5.4 and 3.3 times greater in infants who were not fed nutritionally fortified breast milk (p=.000) or infant formula (p=.001), respectively. Conclusions and Implications: The results of this study emphasize the role that specific factors related to enteral feeding regimens play in the pathogenesis of neonatal comorbidities such as NEC. This sample of preterm infants was less likely to develop NEC after progressing to a point at which enteral feedings were nutritionally fortified. Thus, these findings highlight the need to focus future research on identifying the time at which NEC ensues along the enteral feeding regimen.en_GB
dc.date.available2011-10-27T11:01:18Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T11:01:18Z-
dc.conference.date2007en_US
dc.conference.name19th Annual Scientific Sessionsen_US
dc.conference.hostEastern Nursing Research Societyen_US
dc.conference.locationProvidence, Rhode Island, USAen_US
dc.descriptionConference theme: Building Communities of Scholarship and Research, held April 12-14, 2007 at The Westin Providence.en_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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