Explaining the influence of hope on health in nonlinear relationships among hope, beta-endorphin, and NK cell

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Hdl Handle:
http://hdl.handle.net/10755/163126
Category:
Abstract
Type:
Presentation
Title:
Explaining the influence of hope on health in nonlinear relationships among hope, beta-endorphin, and NK cell
Author(s):
Kim, Dal Sook
Author Details:
Dal Sook Kim, PhD, RN, Chungnam National University, Daejeon, South Korea, email: dskim@cnu.ac.kr
Abstract:
Purpose: The study's purpose were 1) to examine how hope, beta-endorphin as a biomedical mediator of brain to body, and NK cell to destroy tumor cells or virally infected cells are related 2) to explain the effect of hope on health. Theoretical Framework: It assumed hope, beta-endorphin, and N-K cell are communicating bidirectly in the idea of psychoneuroimmunology. Methods (Design, Sample, Setting, Measures, Analysis): The study obtained the results from a convenience sample of 21 female newly diagnosed breast and rectal cancer patients having no drugs in stage 1 or II and just the day before operation or radiation with questionnaire, chart review, and blood sampling. Informed consent was made. Kim & Lee's reliable hope scale for measuring hope, Flow Cytometric analysis of surface expression of NK cell marker CD56 for N-K cell and capillary electrophoresis for beta-endorphin were used. There were no relationships of disease, sampling, and demographic variables to hope, beta-endorphin, and NK cell. Minimum intervals of 15 min from measurement of hope to blood sampling were kept. Results: The relationship pattern of beta-endorphin to hope distinctly transformed at a definite point (13ng/ml of beta-endorphin) from positively to negatively in the figure of parabola on Scatter plot and Curve Estimation. The relationship between beta-endorphin and NK cell figured in parabola at a different point of beta endorphin, not steep especially in post-summit part of parabola. The two groups (the low level: less than 13ng/ml, the high level :above 13ng/ml) were made for appropriate explanation. In the low group, significant positive relationship both of hope to beta-endorphin and hope to N-K cell showed. But, in the high group, there's no significant positive relationship between hope and N-K cell but approaching significant value while Negative relationship between hope and beta-endorphin showed. Conclusions and Implications: The results indicate hope and immune (body) are related through beta-endorphin in nonlinearity and hope influence health positively.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2007
Conference Name:
19th Annual Scientific Sessions
Conference Host:
Eastern Nursing Research Society
Conference Location:
Providence, Rhode Island, USA
Description:
Conference theme: Building Communities of Scholarship and Research, held April 12-14, 2007 at The Westin Providence.
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleExplaining the influence of hope on health in nonlinear relationships among hope, beta-endorphin, and NK cellen_GB
dc.contributor.authorKim, Dal Sooken_US
dc.author.detailsDal Sook Kim, PhD, RN, Chungnam National University, Daejeon, South Korea, email: dskim@cnu.ac.kren_US
dc.identifier.urihttp://hdl.handle.net/10755/163126-
dc.description.abstractPurpose: The study's purpose were 1) to examine how hope, beta-endorphin as a biomedical mediator of brain to body, and NK cell to destroy tumor cells or virally infected cells are related 2) to explain the effect of hope on health. Theoretical Framework: It assumed hope, beta-endorphin, and N-K cell are communicating bidirectly in the idea of psychoneuroimmunology. Methods (Design, Sample, Setting, Measures, Analysis): The study obtained the results from a convenience sample of 21 female newly diagnosed breast and rectal cancer patients having no drugs in stage 1 or II and just the day before operation or radiation with questionnaire, chart review, and blood sampling. Informed consent was made. Kim & Lee's reliable hope scale for measuring hope, Flow Cytometric analysis of surface expression of NK cell marker CD56 for N-K cell and capillary electrophoresis for beta-endorphin were used. There were no relationships of disease, sampling, and demographic variables to hope, beta-endorphin, and NK cell. Minimum intervals of 15 min from measurement of hope to blood sampling were kept. Results: The relationship pattern of beta-endorphin to hope distinctly transformed at a definite point (13ng/ml of beta-endorphin) from positively to negatively in the figure of parabola on Scatter plot and Curve Estimation. The relationship between beta-endorphin and NK cell figured in parabola at a different point of beta endorphin, not steep especially in post-summit part of parabola. The two groups (the low level: less than 13ng/ml, the high level :above 13ng/ml) were made for appropriate explanation. In the low group, significant positive relationship both of hope to beta-endorphin and hope to N-K cell showed. But, in the high group, there's no significant positive relationship between hope and N-K cell but approaching significant value while Negative relationship between hope and beta-endorphin showed. Conclusions and Implications: The results indicate hope and immune (body) are related through beta-endorphin in nonlinearity and hope influence health positively.en_GB
dc.date.available2011-10-27T11:01:46Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T11:01:46Z-
dc.conference.date2007en_US
dc.conference.name19th Annual Scientific Sessionsen_US
dc.conference.hostEastern Nursing Research Societyen_US
dc.conference.locationProvidence, Rhode Island, USAen_US
dc.descriptionConference theme: Building Communities of Scholarship and Research, held April 12-14, 2007 at The Westin Providence.en_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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