2.50
Hdl Handle:
http://hdl.handle.net/10755/163291
Category:
Abstract
Type:
Presentation
Title:
The Symptom Experience of HIV/HCV Co-Infected Adults
Author(s):
Bova, Carol; Ogawa, Lisa; Jaffarian, Carol
Author Details:
Carol Bova, PhD, RN, ANP, University of Massachusetts, Worcester, Massachusetts, USA, email: carol.bova@umassmed.edu; Lisa Ogawa, MS, RN; Carol Jaffarian, MS, RN, ANP
Abstract:
Purpose: The purpose of this study was to describe the symptom experience of HIV/HCV co-infected adults at entry into a longitudinal multi-method study. Background: Chronic hepatitis C virus (HCV) infection affects between 150,000 to 300,000 HIV positive adults in the United States. Both HIV and HCV are characterized by a range of clinical signs and symptoms. However, little is known about the actual symptom burden associated with HIV/HCV co-infection. Methods (Design, Participants, Setting, Data Collection, Analytic approach): This study used a cross-sectional, descriptive, multi-method design. Purposive sampling was done to recruit adults with chronic HCV from three HIV specialty clinics. A standardized symptom experience inventory (HIV-SEI; alpha = .86) and qualitative in-depth interviews were used. Results: 39 HIV/HCV co-infected adults were enrolled in the study. The mean age of the participants was 44.7 years, 48.7% were female, 54% were racial or ethnic minorities, 33% had AIDS, 73% had HCV genotype 1, and 95% had a history of substance abuse. The mean number of symptoms experienced was 10.1 (range = 2-19) with a mean total symptom experience score of 18.6 (range = 2-47). The most common symptoms included fatigue (75%), dyspnea (72%), muscle aches (70%), insomnia (68%), pain (65%), bone aches (65%) and headache (63%). Symptom scores were significantly higher for women (p < .01) and persons with mental illness (p < .001). Symptom scores did not differ by HIV illness stage (p = .26). Qualitative data revealed that participants experienced profound fatigue and had trouble differentiating HIV from HCV-related symptoms. Conclusions and Implications: HIV/HCV co-infected adults experience a significant constellation of symptoms; with fatigue, dyspnea, sleep disturbances, and pain syndromes being the most prominent. Research is needed to test interventions that ease this symptom burden and examine whether HCV treatment influences the symptom experience of co-infected adults.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2007
Conference Name:
19th Annual Scientific Sessions
Conference Host:
Eastern Nursing Research Society
Conference Location:
Providence, Rhode Island, USA
Description:
Conference theme: Building Communities of Scholarship and Research, held April 12-14, 2007 at The Westin Providence.
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleThe Symptom Experience of HIV/HCV Co-Infected Adultsen_GB
dc.contributor.authorBova, Carolen_US
dc.contributor.authorOgawa, Lisaen_US
dc.contributor.authorJaffarian, Carolen_US
dc.author.detailsCarol Bova, PhD, RN, ANP, University of Massachusetts, Worcester, Massachusetts, USA, email: carol.bova@umassmed.edu; Lisa Ogawa, MS, RN; Carol Jaffarian, MS, RN, ANPen_US
dc.identifier.urihttp://hdl.handle.net/10755/163291-
dc.description.abstractPurpose: The purpose of this study was to describe the symptom experience of HIV/HCV co-infected adults at entry into a longitudinal multi-method study. Background: Chronic hepatitis C virus (HCV) infection affects between 150,000 to 300,000 HIV positive adults in the United States. Both HIV and HCV are characterized by a range of clinical signs and symptoms. However, little is known about the actual symptom burden associated with HIV/HCV co-infection. Methods (Design, Participants, Setting, Data Collection, Analytic approach): This study used a cross-sectional, descriptive, multi-method design. Purposive sampling was done to recruit adults with chronic HCV from three HIV specialty clinics. A standardized symptom experience inventory (HIV-SEI; alpha = .86) and qualitative in-depth interviews were used. Results: 39 HIV/HCV co-infected adults were enrolled in the study. The mean age of the participants was 44.7 years, 48.7% were female, 54% were racial or ethnic minorities, 33% had AIDS, 73% had HCV genotype 1, and 95% had a history of substance abuse. The mean number of symptoms experienced was 10.1 (range = 2-19) with a mean total symptom experience score of 18.6 (range = 2-47). The most common symptoms included fatigue (75%), dyspnea (72%), muscle aches (70%), insomnia (68%), pain (65%), bone aches (65%) and headache (63%). Symptom scores were significantly higher for women (p < .01) and persons with mental illness (p < .001). Symptom scores did not differ by HIV illness stage (p = .26). Qualitative data revealed that participants experienced profound fatigue and had trouble differentiating HIV from HCV-related symptoms. Conclusions and Implications: HIV/HCV co-infected adults experience a significant constellation of symptoms; with fatigue, dyspnea, sleep disturbances, and pain syndromes being the most prominent. Research is needed to test interventions that ease this symptom burden and examine whether HCV treatment influences the symptom experience of co-infected adults.en_GB
dc.date.available2011-10-27T11:04:50Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T11:04:50Z-
dc.conference.date2007en_US
dc.conference.name19th Annual Scientific Sessionsen_US
dc.conference.hostEastern Nursing Research Societyen_US
dc.conference.locationProvidence, Rhode Island, USAen_US
dc.descriptionConference theme: Building Communities of Scholarship and Research, held April 12-14, 2007 at The Westin Providence.en_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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