Efficacy of Cryotherapy on Oral Mucositis in Autologous Stem Cell Transplant Patients: A Pilot Randomized Trial

2.50
Hdl Handle:
http://hdl.handle.net/10755/164800
Category:
Abstract
Type:
Presentation
Title:
Efficacy of Cryotherapy on Oral Mucositis in Autologous Stem Cell Transplant Patients: A Pilot Randomized Trial
Author(s):
Salvador, Prisco; Howell, Doris; Buco, Christina
Author Details:
Prisco Salvador, RN, MSc, Staff RN, University Health Network/Princess Margaret Hospital site, Toronto, Ontario, Canada, email: prisco.salvador@uhn.on.ca; Doris Howell, RN, PhD; Christina Buco, RN
Abstract:
Research Study: Oral mucositis remains a significant problem for autologous stem cell transplant (ASCT) patients. The systematic application of an oral care protocol and oral cryotherapy in populations other than ASCT are the most effective non-pharmacological options available in the practice setting. The potential effectiveness of oral cryotherapy in tandem with an established oral care protocol in the ASCT population has not been adequately examined. The purpose of this pilot randomized trial was to determine the efficacy of oral cryotherapy plus a systematic oral care on outcomes that include oral mucositis severity, mucositis-related pain, ability to eat and drink, tolerability of oral cryotherapy, and length of hospital stay (LOS) in ASCT patients. An oral care intervention model was developed, based on Neuman Systems Model, to underpin this research project. Patients were recruited from a hospitalÆs inpatient unit. Patients in the experimental group were asked to suck on ice chips for 60 minutesùfive minutes before, 30 minutes during, and 25 minutes after melphalan. All study patients received a standard oral care protocol. Each patient was assessed on day -1, 3, 6, 9, and 12 using a data collection tool developed and validated for the purpose of the study. Data analysis was completed using a SAS software package. Forty five patients with multiple myeloma for ASCT were randomized to oral self-care alone (n=22) or oral self-care plus cryotherapy (n=23). Oral mucositis severity scores, in OMAS and WHO scales, for the experimental group were significantly different than the control group with p-values of 0.001 and 0.006 respectively. Mouth/throat pain scores for the experimental group was significantly different than the control group (p=0.009). There was no significant difference between groups on functional outcomes of food and fluid intake scores (p=0.91). Oral cryotherapy was well tolerated by patients in the experimental group. A one day shorter non-statistical difference in LOS was noted for the experimental arm patients. In conclusion, oral cryotherapy plus an oral self-care protocol may offer beneficial results over and above systematic oral care alone in ASCT patients.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2009
Conference Name:
34th Annual Oncology Nursing Society Congress
Conference Host:
Oncology Nursing Society
Conference Location:
San Antonio, Texas, USA
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleEfficacy of Cryotherapy on Oral Mucositis in Autologous Stem Cell Transplant Patients: A Pilot Randomized Trialen_GB
dc.contributor.authorSalvador, Priscoen_US
dc.contributor.authorHowell, Dorisen_US
dc.contributor.authorBuco, Christinaen_US
dc.author.detailsPrisco Salvador, RN, MSc, Staff RN, University Health Network/Princess Margaret Hospital site, Toronto, Ontario, Canada, email: prisco.salvador@uhn.on.ca; Doris Howell, RN, PhD; Christina Buco, RNen_US
dc.identifier.urihttp://hdl.handle.net/10755/164800-
dc.description.abstractResearch Study: Oral mucositis remains a significant problem for autologous stem cell transplant (ASCT) patients. The systematic application of an oral care protocol and oral cryotherapy in populations other than ASCT are the most effective non-pharmacological options available in the practice setting. The potential effectiveness of oral cryotherapy in tandem with an established oral care protocol in the ASCT population has not been adequately examined. The purpose of this pilot randomized trial was to determine the efficacy of oral cryotherapy plus a systematic oral care on outcomes that include oral mucositis severity, mucositis-related pain, ability to eat and drink, tolerability of oral cryotherapy, and length of hospital stay (LOS) in ASCT patients. An oral care intervention model was developed, based on Neuman Systems Model, to underpin this research project. Patients were recruited from a hospitalÆs inpatient unit. Patients in the experimental group were asked to suck on ice chips for 60 minutesùfive minutes before, 30 minutes during, and 25 minutes after melphalan. All study patients received a standard oral care protocol. Each patient was assessed on day -1, 3, 6, 9, and 12 using a data collection tool developed and validated for the purpose of the study. Data analysis was completed using a SAS software package. Forty five patients with multiple myeloma for ASCT were randomized to oral self-care alone (n=22) or oral self-care plus cryotherapy (n=23). Oral mucositis severity scores, in OMAS and WHO scales, for the experimental group were significantly different than the control group with p-values of 0.001 and 0.006 respectively. Mouth/throat pain scores for the experimental group was significantly different than the control group (p=0.009). There was no significant difference between groups on functional outcomes of food and fluid intake scores (p=0.91). Oral cryotherapy was well tolerated by patients in the experimental group. A one day shorter non-statistical difference in LOS was noted for the experimental arm patients. In conclusion, oral cryotherapy plus an oral self-care protocol may offer beneficial results over and above systematic oral care alone in ASCT patients.en_GB
dc.date.available2011-10-27T12:07:14Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T12:07:14Z-
dc.conference.date2009en_US
dc.conference.name34th Annual Oncology Nursing Society Congressen_US
dc.conference.hostOncology Nursing Societyen_US
dc.conference.locationSan Antonio, Texas, USAen_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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