PREVENTION OF FALLS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL BREAST CANCER SURVIVORS

2.50
Hdl Handle:
http://hdl.handle.net/10755/165163
Category:
Abstract
Type:
Presentation
Title:
PREVENTION OF FALLS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL BREAST CANCER SURVIVORS
Author(s):
Waltman, Nancy; Gross, Gloria; Lindsey, Ada; Ott, Carol; Twiss, Janice; Berg, Kris
Author Details:
Nancy Waltman, PhD, APRN, Associate Professor, University of Nebraska College of Nursing, Lincoln, Nebraska, USA, email: nwaltman@unmc.edu; Gloria Gross; Ada Lindsey; Carol Ott; Janice Twiss; Kris Berg
Abstract:
Topic: Major consequences of osteoporosis are fractures caused by low bone mineral density (BMD) and by falls. Breast cancer survivors (BCS) are at risk for osteoporosis because cancer treatments can cause early-onset menopause and early bone loss (low BMD). To prevent fractures in BCS, interventions need to address prevention of falls as well as improvement in BMD. Purpose: This study compared effectiveness of a two treatment group intervention (G1, G2) in preventing falls and fractures in 174 postmenopausal BCS. Framework: Facilitative strategies based on Bandura's (1997) Self-Efficacy Theory promoted adherence to intervention components in both G1 and G2 groups. Methods: Postmenopausal women with history of stage 0, I, or II breast cancer and with low BMD were randomly assigned to one of two treatment groups (G1 or G2). Both groups received risedronate, calcium, and vitamin D for 24 months. G1 subjects also participated in strength/weight training exercises (SWTE). Outcomes at 6 and/or 12-month intervals included muscle strength (Biodex), dynamic balance (backward tandem walk), falls, fractures, and BMD, and differences between groups were analyzed using ANCOVA. Findings: Findings are reported for first 12 months in an ongoing 24-month intervention, and BMD results are not included. Mean age of G1 (SWTE) group women (n = 81) was 58.7 (7.4) years compared to 58.5 (7.6) years in G2 group (n = 91). Mean time since menopause or HRT for G1 group was 6.8 (6.5) years compared to 7.8 (7.6) years in G2 group. Women in the G1 group had significantly improved balance [F (2,171) = 2.38, p = .007] and muscle strength for hip flexion [F (2,171) = 3.08, p= .04]. Differences in knee flexion [F (2,171) = 2.38, p = .09] and knee extension [F (2,171) = 2.34, p=.09] approached significance. Twenty-six of 81 G1 subjects reported a total of 40 falls and 32 of 93 G2 subjects reported 58 falls. Twenty percent of G2 subjects had multiple falls compared to less than 7% of G1 subjects (p =.01). G1 subjects had one fracture (right wrist) and G2 subjects had two fractures (left ankle and patella). Implications will be discussed at the presentation.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2006
Conference Name:
31st Annual Oncology Nursing Society Congress
Conference Host:
Oncology Nursing Society
Conference Location:
Boston, Massachusetts, USA
Sponsors:
Funding Sources: Aventis/Proctor & Gamble, Wyeth, and NIH/NINR.
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titlePREVENTION OF FALLS AND OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL BREAST CANCER SURVIVORSen_GB
dc.contributor.authorWaltman, Nancyen_US
dc.contributor.authorGross, Gloriaen_US
dc.contributor.authorLindsey, Adaen_US
dc.contributor.authorOtt, Carolen_US
dc.contributor.authorTwiss, Janiceen_US
dc.contributor.authorBerg, Krisen_US
dc.author.detailsNancy Waltman, PhD, APRN, Associate Professor, University of Nebraska College of Nursing, Lincoln, Nebraska, USA, email: nwaltman@unmc.edu; Gloria Gross; Ada Lindsey; Carol Ott; Janice Twiss; Kris Bergen_US
dc.identifier.urihttp://hdl.handle.net/10755/165163-
dc.description.abstractTopic: Major consequences of osteoporosis are fractures caused by low bone mineral density (BMD) and by falls. Breast cancer survivors (BCS) are at risk for osteoporosis because cancer treatments can cause early-onset menopause and early bone loss (low BMD). To prevent fractures in BCS, interventions need to address prevention of falls as well as improvement in BMD. Purpose: This study compared effectiveness of a two treatment group intervention (G1, G2) in preventing falls and fractures in 174 postmenopausal BCS. Framework: Facilitative strategies based on Bandura's (1997) Self-Efficacy Theory promoted adherence to intervention components in both G1 and G2 groups. Methods: Postmenopausal women with history of stage 0, I, or II breast cancer and with low BMD were randomly assigned to one of two treatment groups (G1 or G2). Both groups received risedronate, calcium, and vitamin D for 24 months. G1 subjects also participated in strength/weight training exercises (SWTE). Outcomes at 6 and/or 12-month intervals included muscle strength (Biodex), dynamic balance (backward tandem walk), falls, fractures, and BMD, and differences between groups were analyzed using ANCOVA. Findings: Findings are reported for first 12 months in an ongoing 24-month intervention, and BMD results are not included. Mean age of G1 (SWTE) group women (n = 81) was 58.7 (7.4) years compared to 58.5 (7.6) years in G2 group (n = 91). Mean time since menopause or HRT for G1 group was 6.8 (6.5) years compared to 7.8 (7.6) years in G2 group. Women in the G1 group had significantly improved balance [F (2,171) = 2.38, p = .007] and muscle strength for hip flexion [F (2,171) = 3.08, p= .04]. Differences in knee flexion [F (2,171) = 2.38, p = .09] and knee extension [F (2,171) = 2.34, p=.09] approached significance. Twenty-six of 81 G1 subjects reported a total of 40 falls and 32 of 93 G2 subjects reported 58 falls. Twenty percent of G2 subjects had multiple falls compared to less than 7% of G1 subjects (p =.01). G1 subjects had one fracture (right wrist) and G2 subjects had two fractures (left ankle and patella). Implications will be discussed at the presentation.en_GB
dc.date.available2011-10-27T12:13:39Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T12:13:39Z-
dc.conference.date2006en_US
dc.conference.name31st Annual Oncology Nursing Society Congressen_US
dc.conference.hostOncology Nursing Societyen_US
dc.conference.locationBoston, Massachusetts, USAen_US
dc.description.sponsorshipFunding Sources: Aventis/Proctor & Gamble, Wyeth, and NIH/NINR.-
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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