2.50
Hdl Handle:
http://hdl.handle.net/10755/165189
Category:
Abstract
Type:
Presentation
Title:
CONFLICT OF INTEREST: MORE THAN YOU THINK
Author(s):
Brown, Sally
Author Details:
Sally Brown, RN BSN MGA OCN CCRP, Coordinator, Research Protocols, Franklin Square Hospital Center, Baltimore, Maryland, USA, email: sally.brown@medstar.net
Abstract:
Conflict of interest is inherent in clinical research. The concept has come under increased scrutiny in recent years as clinical research has expanded from academic centers to community hospitals and private physicians' offices. The most visual form of conflict of interest is financial as the majority of oncology research receives external financial support. Cooperative trials groups and pharmaceutical and device companies provide financial support for entering patients into clinical trials. Cooperative trials groups are increasing their collaboration with and funding from industry sources. This escalates the potential for conflict of interest in cooperative group studies. Physicians may have a financial stake in the success of the involved pharmaceutical or device company by holding stock or functioning as a private contractor with a company by participating in a speakersÆ bureau or on an advisory board. Conflict of interest does not necessarily mean there is inappropriate conduct, but it could be viewed as potentially inappropriate. Non-financial conflict of interest is less visual involving coordinators as well as investigators. Coordinators have a potential conflict of interest if accrual and delinquency rates are linked to evaluations and promotions. The need or desire to publish paradigm-changing results can be perceived as conflict of interest in the conduct of research. Another form of conflict of interest is physician-investigator confusion. If the treating physician is also the research investigator, the patient who has confidence in his/her physician, has the potential to agree to participate in research in order to maintain that relationship with the physician. Several authorities have addressed aspects of financial disclosure. There remains a need to determine the degree of disclosure that should be presented to potential participants. Exploration of the consequences of non-financial conflict of interest and the development of methods to reduce any impact are needed.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2007
Conference Name:
32nd Annual Oncology Nursing Society Congress
Conference Host:
Oncology Nursing Society
Conference Location:
Las Vegas, Nevada, USA
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleCONFLICT OF INTEREST: MORE THAN YOU THINKen_GB
dc.contributor.authorBrown, Sallyen_US
dc.author.detailsSally Brown, RN BSN MGA OCN CCRP, Coordinator, Research Protocols, Franklin Square Hospital Center, Baltimore, Maryland, USA, email: sally.brown@medstar.neten_US
dc.identifier.urihttp://hdl.handle.net/10755/165189-
dc.description.abstractConflict of interest is inherent in clinical research. The concept has come under increased scrutiny in recent years as clinical research has expanded from academic centers to community hospitals and private physicians' offices. The most visual form of conflict of interest is financial as the majority of oncology research receives external financial support. Cooperative trials groups and pharmaceutical and device companies provide financial support for entering patients into clinical trials. Cooperative trials groups are increasing their collaboration with and funding from industry sources. This escalates the potential for conflict of interest in cooperative group studies. Physicians may have a financial stake in the success of the involved pharmaceutical or device company by holding stock or functioning as a private contractor with a company by participating in a speakersÆ bureau or on an advisory board. Conflict of interest does not necessarily mean there is inappropriate conduct, but it could be viewed as potentially inappropriate. Non-financial conflict of interest is less visual involving coordinators as well as investigators. Coordinators have a potential conflict of interest if accrual and delinquency rates are linked to evaluations and promotions. The need or desire to publish paradigm-changing results can be perceived as conflict of interest in the conduct of research. Another form of conflict of interest is physician-investigator confusion. If the treating physician is also the research investigator, the patient who has confidence in his/her physician, has the potential to agree to participate in research in order to maintain that relationship with the physician. Several authorities have addressed aspects of financial disclosure. There remains a need to determine the degree of disclosure that should be presented to potential participants. Exploration of the consequences of non-financial conflict of interest and the development of methods to reduce any impact are needed.en_GB
dc.date.available2011-10-27T12:14:06Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T12:14:06Z-
dc.conference.date2007en_US
dc.conference.name32nd Annual Oncology Nursing Society Congressen_US
dc.conference.hostOncology Nursing Societyen_US
dc.conference.locationLas Vegas, Nevada, USAen_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
All Items in this repository are protected by copyright, with all rights reserved, unless otherwise indicated.