THE EFFECT OF NEUTROPENIA ON A COGNITIVE BEHAVIORAL INTERVENTION FOR SYMPTOM MANAGEMENT

2.50
Hdl Handle:
http://hdl.handle.net/10755/165270
Category:
Abstract
Type:
Presentation
Title:
THE EFFECT OF NEUTROPENIA ON A COGNITIVE BEHAVIORAL INTERVENTION FOR SYMPTOM MANAGEMENT
Author(s):
Given, Barbara; Given, Charles; Kozachik, Sharon; Jeon, Sangchoon; Sikorskii, Alla
Author Details:
Barbara Given, PhD, RN, FAAN, Michgan State University, East Lansing, Michigan, USA; Charles Given, PhD; Sharon Kozachik; Sangchoon Jeon; Alla Sikorskii
Abstract:
Trials of cognitive behavioral interventions designed to reduce symptom severity or improve dimensions of quality of life seldom consider the toxic effects of treatment moderate the impact of the trial on the designated outcome. To address this issue, the moderating effect of neutropenia on the impact of a cognitive behavioral intervention for reducing symptom severity is evaluated among cancer patients undergoing a first course of chemotherapy. The intervention was based on Cognitive Behavioral Theory and focused on problem solving and decision making intervention strategies, self care information, counseling and support, and communication with providers. A randomized 10 contact, 20-week trial of a nurse delivered cognitive behavioral intervention on symptom severity is described, and the moderating effects of a neutropenia episode on symptom severity at 20 weeks are evaluated. There were 118 experimental patients and 119 controls who had a diagnosis of solid tumors. Symptom severity scores were based on sum scores (0-10) for 15 symptoms. Data collection interviews were carried out at baseline, 10, 20, and 32 weeks. Sites and stages of cancer and neutropenia episodes were obtained through an audit of patients medical records. To determine the presence of neutropenia and how it moderates the impact of the intervention on symptom severity, we examined both the main effect for the intervention and neutropenia as well as the interaction between intervention group and neutropenic using a General Linear Model. There was an effect for age (younger) and group on severity at 20 weeks and an interaction between neutropenia and group. Among patients with no evidence of neutropenia, those in the experimental group had a 9-point lower severity score. Among patients who experienced neutropenia, differences in symptom severity by intervention group were less than 3 points. Further, fatigue, fever, and pain were more prevalent among patients with neutropenia. Patients who experience neutropenia do not benefit from a cognitive behavioral intervention to lower symptoms. The overall effect of this intervention comes almost exclusively from patients without neutropenia. These data indicate the importance of incorporating clinical measures of toxicity when attempting to evaluate behavioral interventions.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2005
Conference Name:
30th Annual Oncology Nursing Society Congress
Conference Host:
Oncology Nursing Society
Conference Location:
Orlando, Florida, USA
Sponsors:
Funding Sources: National Cancer Institute.
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleTHE EFFECT OF NEUTROPENIA ON A COGNITIVE BEHAVIORAL INTERVENTION FOR SYMPTOM MANAGEMENTen_GB
dc.contributor.authorGiven, Barbaraen_US
dc.contributor.authorGiven, Charlesen_US
dc.contributor.authorKozachik, Sharonen_US
dc.contributor.authorJeon, Sangchoonen_US
dc.contributor.authorSikorskii, Allaen_US
dc.author.detailsBarbara Given, PhD, RN, FAAN, Michgan State University, East Lansing, Michigan, USA; Charles Given, PhD; Sharon Kozachik; Sangchoon Jeon; Alla Sikorskiien_US
dc.identifier.urihttp://hdl.handle.net/10755/165270-
dc.description.abstractTrials of cognitive behavioral interventions designed to reduce symptom severity or improve dimensions of quality of life seldom consider the toxic effects of treatment moderate the impact of the trial on the designated outcome. To address this issue, the moderating effect of neutropenia on the impact of a cognitive behavioral intervention for reducing symptom severity is evaluated among cancer patients undergoing a first course of chemotherapy. The intervention was based on Cognitive Behavioral Theory and focused on problem solving and decision making intervention strategies, self care information, counseling and support, and communication with providers. A randomized 10 contact, 20-week trial of a nurse delivered cognitive behavioral intervention on symptom severity is described, and the moderating effects of a neutropenia episode on symptom severity at 20 weeks are evaluated. There were 118 experimental patients and 119 controls who had a diagnosis of solid tumors. Symptom severity scores were based on sum scores (0-10) for 15 symptoms. Data collection interviews were carried out at baseline, 10, 20, and 32 weeks. Sites and stages of cancer and neutropenia episodes were obtained through an audit of patients medical records. To determine the presence of neutropenia and how it moderates the impact of the intervention on symptom severity, we examined both the main effect for the intervention and neutropenia as well as the interaction between intervention group and neutropenic using a General Linear Model. There was an effect for age (younger) and group on severity at 20 weeks and an interaction between neutropenia and group. Among patients with no evidence of neutropenia, those in the experimental group had a 9-point lower severity score. Among patients who experienced neutropenia, differences in symptom severity by intervention group were less than 3 points. Further, fatigue, fever, and pain were more prevalent among patients with neutropenia. Patients who experience neutropenia do not benefit from a cognitive behavioral intervention to lower symptoms. The overall effect of this intervention comes almost exclusively from patients without neutropenia. These data indicate the importance of incorporating clinical measures of toxicity when attempting to evaluate behavioral interventions.en_GB
dc.date.available2011-10-27T12:15:32Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T12:15:32Z-
dc.conference.date2005en_US
dc.conference.name30th Annual Oncology Nursing Society Congressen_US
dc.conference.hostOncology Nursing Societyen_US
dc.conference.locationOrlando, Florida, USAen_US
dc.description.sponsorshipFunding Sources: National Cancer Institute.-
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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