2.50
Hdl Handle:
http://hdl.handle.net/10755/165348
Category:
Abstract
Type:
Presentation
Title:
Chemotherapy Handling and Effects Among Nurses and Their Offspring
Author(s):
Martin, S.
Author Details:
S. Martin, Oncology Nursing Consultant, Long Beach, New York, USA
Abstract:
The use of antineoplastic chemotherapeutic agents for the treatment of cancer and some other non-neoplastic diseases has expanded widely during the past several decades. There is growing concern regarding the safety of healthcare workers who handle these agents. The literature has described adverse health effects such as chromosomal aberrations, reproductive dysfunction, and acute symptomatology. At present, the literature is lacking research that investigates the occupational exposure to chemotherapy and potential adverse effects among nurses¡¦ offspring. Purpose: This investigation studied whether there was an association between maternal occupational antineoplastic chemotherapeutic exposure and learning disabilities among offspring as well as infertility, miscarriage and pregnancy and birth complications among oncology nurses. Theoretical/Scientific Framework: The conceptual framework of the epidemiologic triad where adverse health effects is a product of an interaction between the person at risk (host), an exposure to antineoplastic chemotherapeutic (agent), and the environment (availability of resources). Methods: This epidemiological retrospective survey case-control design surveyed 7500 members of the Oncology Nursing Society using a self-report mailed survey. Data Analysis: Non-parametric testing (Chi square) was used to estimate the prevalence of dependent variables. Logistic regression was used to compare prevalence of the dependent variables, adjusting for the effects of interactions, confounders or other risk factors. Findings and Implications: The response rate was 50 %. Controlling for risk factors, significant associations were reported with chemotherapy handling and infertility in nurses who handled chemotherapy before the age of 25 (OR = 1.42, 95 % CI = 1.05 -1.91), and miscarriages (OR = 1.01, 95 % CI = 1.001 -1.02). Preterm labor was associated with administering nine or greater doses of chemotherapy per day (OR = 2.98, 95 % CI = 1.75 -5.04) and preterm births were associated with preparing nine or greater doses per day (OR = 5.56, 95 % CI = 1.96 -15.78). Learning disabilities were associated with the frequency of glove use (OR = 2.56, 95 % CI = 1.75 -3.72). Specific learning disabilities including motor (OR = 2.53, 95 % CI = 1.30 -4.91), cognitive (OR = 2.25, 95 % CI = 1.22 -4.17), ADHD (OR =1.88, 95 % CI = 1.07 -3.30), and speech (OR = 2.47, 95 % CI = 1.58 -3.85) were significant. These findings raise many questions regarding the potential long-term effects of chemotherapy handling on both oncology nurses and their offspring.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2005
Conference Name:
30th Annual Oncology Nursing Society Congress
Conference Host:
Oncology Nursing Society
Conference Location:
Orlando, Florida, USA
Sponsors:
Funding Sources: Oncology Nursing Foundation AMGEN (Funded Doctoral Fellowship)
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleChemotherapy Handling and Effects Among Nurses and Their Offspringen_GB
dc.contributor.authorMartin, S.en_US
dc.author.detailsS. Martin, Oncology Nursing Consultant, Long Beach, New York, USAen_US
dc.identifier.urihttp://hdl.handle.net/10755/165348-
dc.description.abstractThe use of antineoplastic chemotherapeutic agents for the treatment of cancer and some other non-neoplastic diseases has expanded widely during the past several decades. There is growing concern regarding the safety of healthcare workers who handle these agents. The literature has described adverse health effects such as chromosomal aberrations, reproductive dysfunction, and acute symptomatology. At present, the literature is lacking research that investigates the occupational exposure to chemotherapy and potential adverse effects among nurses¡¦ offspring. Purpose: This investigation studied whether there was an association between maternal occupational antineoplastic chemotherapeutic exposure and learning disabilities among offspring as well as infertility, miscarriage and pregnancy and birth complications among oncology nurses. Theoretical/Scientific Framework: The conceptual framework of the epidemiologic triad where adverse health effects is a product of an interaction between the person at risk (host), an exposure to antineoplastic chemotherapeutic (agent), and the environment (availability of resources). Methods: This epidemiological retrospective survey case-control design surveyed 7500 members of the Oncology Nursing Society using a self-report mailed survey. Data Analysis: Non-parametric testing (Chi square) was used to estimate the prevalence of dependent variables. Logistic regression was used to compare prevalence of the dependent variables, adjusting for the effects of interactions, confounders or other risk factors. Findings and Implications: The response rate was 50 %. Controlling for risk factors, significant associations were reported with chemotherapy handling and infertility in nurses who handled chemotherapy before the age of 25 (OR = 1.42, 95 % CI = 1.05 -1.91), and miscarriages (OR = 1.01, 95 % CI = 1.001 -1.02). Preterm labor was associated with administering nine or greater doses of chemotherapy per day (OR = 2.98, 95 % CI = 1.75 -5.04) and preterm births were associated with preparing nine or greater doses per day (OR = 5.56, 95 % CI = 1.96 -15.78). Learning disabilities were associated with the frequency of glove use (OR = 2.56, 95 % CI = 1.75 -3.72). Specific learning disabilities including motor (OR = 2.53, 95 % CI = 1.30 -4.91), cognitive (OR = 2.25, 95 % CI = 1.22 -4.17), ADHD (OR =1.88, 95 % CI = 1.07 -3.30), and speech (OR = 2.47, 95 % CI = 1.58 -3.85) were significant. These findings raise many questions regarding the potential long-term effects of chemotherapy handling on both oncology nurses and their offspring.en_GB
dc.date.available2011-10-27T12:16:56Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T12:16:56Z-
dc.conference.date2005en_US
dc.conference.name30th Annual Oncology Nursing Society Congressen_US
dc.conference.hostOncology Nursing Societyen_US
dc.conference.locationOrlando, Florida, USAen_US
dc.description.sponsorshipFunding Sources: Oncology Nursing Foundation AMGEN (Funded Doctoral Fellowship)-
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
All Items in this repository are protected by copyright, with all rights reserved, unless otherwise indicated.