CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY (CIPN): PATIENT PERSPECTIVES ON WHETHER TO CONTINUE NEUROTOXIC TREATMENT

2.50
Hdl Handle:
http://hdl.handle.net/10755/165365
Category:
Abstract
Type:
Presentation
Title:
CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY (CIPN): PATIENT PERSPECTIVES ON WHETHER TO CONTINUE NEUROTOXIC TREATMENT
Author(s):
Bakitas, Marie
Author Details:
Marie Bakitas, DNSc, ARNP, AOCN, FAAN, Nurse Practitioner, Palliative Care, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA, email: marie.bakitas@dartmouth.edu
Abstract:
Topic: Chemotherapy-induced peripheral neuropathy is a common, but understudied dose-limiting toxicity of chemotherapy. CIPN incidence ranges from 10-100% depending on the drug(s), dose(s), patient factors, and measurement system. Empirical reports using quantitative objective measures identify a wide spectrum of impact from "minimal" to "devastating"; however subjective data is lacking regarding specific symptoms and the impact on everyday life. As a result, CIPN has been identified as a priority symptom within the 2005-09 ONS-Research Agenda. Purpose: The overall purpose of the current study was to describe patient's perspectives on the symptom experience and the impact of symptoms on everyday life. A secondary aim was to understand the influence of symptoms on treatment decision-making. Framework: Current measures do not capture the clinically relevant patient perspective on the subjective CIPN experience. In order to address this gap, the naturalistic paradigm (Lincoln & Guba, 1985) was chosen to give voice to previously unrevealed, in-depth aspects of the symptom experience and how these effects influence everyday life, and decisions about whether to continue neurotoxic treatments. Methods: This exploratory, qualitative descriptive study identified CIPN symptoms and their effect on everyday life. Verbatim transcribed interviews were coded and analyzed using Atlas-TI software. A progressive process of classifying, comparing, grouping, and refining data resulted in patterns, relationships, and themes that provided insights about symptoms, and CIPN impact on everyday life and treatment decisions. Conceptual redundancy (saturation) was reached after 28 interviews. Findings: Five over-arching themes emerged that provided a comprehensive understanding of CIPN symptoms, functional effects, and treatment decision-making. This presentation will focus on the over-arching theme of "Making Choices". Sub themes included: "Thinking it Through", "Doing Whatever it Takes", and "Changing Course". Currently, subjective symptom reports and function are the determining factors in chemotherapy dose reduction or discontinuation. However, little is known about how this process occurs. The current study adds to our understanding of the patient's perspective on that process including insights about how clinicians approached this process and how patient's weighed CIPN symptoms with their (or the clinician's) desire to continue beneficial, but neurotoxic chemotherapy.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2006
Conference Name:
31st Annual Oncology Nursing Society Congress
Conference Host:
Oncology Nursing Society
Conference Location:
Boston, Massachusetts, USA
Sponsors:
Funding Sources: Department of Defense, Breast Cancer Research Program.
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleCHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY (CIPN): PATIENT PERSPECTIVES ON WHETHER TO CONTINUE NEUROTOXIC TREATMENTen_GB
dc.contributor.authorBakitas, Marieen_US
dc.author.detailsMarie Bakitas, DNSc, ARNP, AOCN, FAAN, Nurse Practitioner, Palliative Care, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA, email: marie.bakitas@dartmouth.eduen_US
dc.identifier.urihttp://hdl.handle.net/10755/165365-
dc.description.abstractTopic: Chemotherapy-induced peripheral neuropathy is a common, but understudied dose-limiting toxicity of chemotherapy. CIPN incidence ranges from 10-100% depending on the drug(s), dose(s), patient factors, and measurement system. Empirical reports using quantitative objective measures identify a wide spectrum of impact from "minimal" to "devastating"; however subjective data is lacking regarding specific symptoms and the impact on everyday life. As a result, CIPN has been identified as a priority symptom within the 2005-09 ONS-Research Agenda. Purpose: The overall purpose of the current study was to describe patient's perspectives on the symptom experience and the impact of symptoms on everyday life. A secondary aim was to understand the influence of symptoms on treatment decision-making. Framework: Current measures do not capture the clinically relevant patient perspective on the subjective CIPN experience. In order to address this gap, the naturalistic paradigm (Lincoln & Guba, 1985) was chosen to give voice to previously unrevealed, in-depth aspects of the symptom experience and how these effects influence everyday life, and decisions about whether to continue neurotoxic treatments. Methods: This exploratory, qualitative descriptive study identified CIPN symptoms and their effect on everyday life. Verbatim transcribed interviews were coded and analyzed using Atlas-TI software. A progressive process of classifying, comparing, grouping, and refining data resulted in patterns, relationships, and themes that provided insights about symptoms, and CIPN impact on everyday life and treatment decisions. Conceptual redundancy (saturation) was reached after 28 interviews. Findings: Five over-arching themes emerged that provided a comprehensive understanding of CIPN symptoms, functional effects, and treatment decision-making. This presentation will focus on the over-arching theme of "Making Choices". Sub themes included: "Thinking it Through", "Doing Whatever it Takes", and "Changing Course". Currently, subjective symptom reports and function are the determining factors in chemotherapy dose reduction or discontinuation. However, little is known about how this process occurs. The current study adds to our understanding of the patient's perspective on that process including insights about how clinicians approached this process and how patient's weighed CIPN symptoms with their (or the clinician's) desire to continue beneficial, but neurotoxic chemotherapy.en_GB
dc.date.available2011-10-27T12:17:14Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T12:17:14Z-
dc.conference.date2006en_US
dc.conference.name31st Annual Oncology Nursing Society Congressen_US
dc.conference.hostOncology Nursing Societyen_US
dc.conference.locationBoston, Massachusetts, USAen_US
dc.description.sponsorshipFunding Sources: Department of Defense, Breast Cancer Research Program.-
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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