2.50
Hdl Handle:
http://hdl.handle.net/10755/165543
Category:
Abstract
Type:
Presentation
Title:
GM-CSF Use For Extravasation of Doxorubicin and Vincristine
Author(s):
Lawrence, Sherry
Author Details:
Sherry Lawrence, Oncology & Hematology Associates, Greenfield, Indiana, USA
Abstract:
Doxorubicin and Vincristine are chemotherapy agents with extensive vesicant properties used in the treatment of certain types of cancers. The usual course of treatment of extravasation is plastic surgery to repair the damaged area. We report a case of Doxorubicin & Vincristine extravasation in an 87-year-old patient with multiple myeloma treated in our clinic. The patient was on a continuous infusion of 15mg\day of Doxorubicin and 0.4mg of Vincristine in a continuous infusion CADD pump through a port. Unfortunately, this patient had an underlying condition of Alzheimer's. He removed the port needle which caused the drug to extravasate into his chest wall, causing a 10 x 12 x 16 cm area of induration which eventually became necrotic on day #3. We treated the patient with 500 mcg of GM-CSF (sargramostim), subcutaneous at four quadrants around the site on days three, six, and 10. On day 10 the area of tissue damage had been reduced to 8 x 3.8 cm and finally to 1.5 x 1.5 cm on day 13. The area on day 13 was dry, healing and scabbed over. GM-CSF has been shown to be effective in the treatment of various skin ulcers, and to date, this is the first reported use of GM-CSF in the U.S. for the treatment of chemo-induced extravasation.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Date:
2002
Conference Name:
27th Annual Oncology Nursing Society Congress
Conference Host:
Oncology Nursing Society
Conference Location:
Washington, D.C., USA
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleGM-CSF Use For Extravasation of Doxorubicin and Vincristineen_GB
dc.contributor.authorLawrence, Sherryen_US
dc.author.detailsSherry Lawrence, Oncology & Hematology Associates, Greenfield, Indiana, USAen_US
dc.identifier.urihttp://hdl.handle.net/10755/165543-
dc.description.abstractDoxorubicin and Vincristine are chemotherapy agents with extensive vesicant properties used in the treatment of certain types of cancers. The usual course of treatment of extravasation is plastic surgery to repair the damaged area. We report a case of Doxorubicin & Vincristine extravasation in an 87-year-old patient with multiple myeloma treated in our clinic. The patient was on a continuous infusion of 15mg\day of Doxorubicin and 0.4mg of Vincristine in a continuous infusion CADD pump through a port. Unfortunately, this patient had an underlying condition of Alzheimer's. He removed the port needle which caused the drug to extravasate into his chest wall, causing a 10 x 12 x 16 cm area of induration which eventually became necrotic on day #3. We treated the patient with 500 mcg of GM-CSF (sargramostim), subcutaneous at four quadrants around the site on days three, six, and 10. On day 10 the area of tissue damage had been reduced to 8 x 3.8 cm and finally to 1.5 x 1.5 cm on day 13. The area on day 13 was dry, healing and scabbed over. GM-CSF has been shown to be effective in the treatment of various skin ulcers, and to date, this is the first reported use of GM-CSF in the U.S. for the treatment of chemo-induced extravasation.en_GB
dc.date.available2011-10-27T12:20:33Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T12:20:33Z-
dc.conference.date2002en_US
dc.conference.name27th Annual Oncology Nursing Society Congressen_US
dc.conference.hostOncology Nursing Societyen_US
dc.conference.locationWashington, D.C., USAen_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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