2.50
Hdl Handle:
http://hdl.handle.net/10755/165847
Category:
Abstract
Type:
Presentation
Title:
Are natural killer cells response to emotional status?
Author(s):
Lewis, Sharon
Author Details:
Sharon Lewis, Professor, University of Texas Health Science Center-San Antonio School of Nursing, San Antonio, Texas, USA, email: lewissl@uthscsa.edu
Abstract:
Emotional distress can alter immune function and predispose an individual to an increased incidence of infectious diseases and cancer. A brief review of studies will focus on how chronic stress depresses the immune system. This brief overview will focus particularly on natural killer (NK) cells, including their function and why they are responsive to an individual's emotional state. Methods to measure NK cell number and function will be compared and discussed. Specific information related to quality control and laboratory measurements will be presented. Ideas will also be presented on when NK cells are an appropriate measurement in a given study design. A program of research will be described that focuses on a relaxation therapy intervention for caregivers of patients with Alzheimer's disease. This research program has shown that caregivers experience a great deal of depression, stress, diminished quality of life, and decreased NK cell number and function as compared to non-caregiver controls. In this study caregivers are taught simple relaxation techniques and studied at 5 different times over a 16-week period. They complete questionnaires that assess physical, mental, social, and emotional health. During each testing session blood was drawn to assess immune function, including NK cell number and function. The results of this study indicate that over the course of the study caregivers had significant improvements in depression, stress, quality of life, and NK cell number and function. These results indicate that a biobehavioral intervention can impact immune function in a group of people who are chronically stressed and have poor immune function.
Repository Posting Date:
27-Oct-2011
Date of Publication:
27-Oct-2011
Conference Host:
Southern Nursing Research Society
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleAre natural killer cells response to emotional status?en_GB
dc.contributor.authorLewis, Sharonen_US
dc.author.detailsSharon Lewis, Professor, University of Texas Health Science Center-San Antonio School of Nursing, San Antonio, Texas, USA, email: lewissl@uthscsa.eduen_US
dc.identifier.urihttp://hdl.handle.net/10755/165847-
dc.description.abstractEmotional distress can alter immune function and predispose an individual to an increased incidence of infectious diseases and cancer. A brief review of studies will focus on how chronic stress depresses the immune system. This brief overview will focus particularly on natural killer (NK) cells, including their function and why they are responsive to an individual's emotional state. Methods to measure NK cell number and function will be compared and discussed. Specific information related to quality control and laboratory measurements will be presented. Ideas will also be presented on when NK cells are an appropriate measurement in a given study design. A program of research will be described that focuses on a relaxation therapy intervention for caregivers of patients with Alzheimer's disease. This research program has shown that caregivers experience a great deal of depression, stress, diminished quality of life, and decreased NK cell number and function as compared to non-caregiver controls. In this study caregivers are taught simple relaxation techniques and studied at 5 different times over a 16-week period. They complete questionnaires that assess physical, mental, social, and emotional health. During each testing session blood was drawn to assess immune function, including NK cell number and function. The results of this study indicate that over the course of the study caregivers had significant improvements in depression, stress, quality of life, and NK cell number and function. These results indicate that a biobehavioral intervention can impact immune function in a group of people who are chronically stressed and have poor immune function.en_GB
dc.date.available2011-10-27T14:34:57Z-
dc.date.issued2011-10-27en_GB
dc.date.accessioned2011-10-27T14:34:57Z-
dc.conference.hostSouthern Nursing Research Societyen_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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