2.50
Hdl Handle:
http://hdl.handle.net/10755/183108
Category:
Abstract
Type:
Presentation
Title:
Does Interferon Therapy Impact the Oral Health of Veterans with Hepatitis C?
Author(s):
Taylor-Young, Patty; Zucker, Betsy; McKeown, Sean; Chang, Michael; Sasaki, Anna
Author Details:
Patty Taylor-Young, PhD, RN,FNP, Portland VA Medical Center, Portland, OR, email: patricia.taylor-young@va.gov; Betsy Zucker, NP; Sean McKeown, DDS; Michael Chang, MD; Anna Sasaki, MD, PhD
Abstract:
Purpose: Anecdotal evidence from experience clinicians suggests that oral health problems occur in veterans undergoing interferon therapy for hepatitis C (HCV). However, there has been no prospective investigation of this association.
This study will expand knowledge regarding the oral health of veterans with HCV and provide new knowledge regarding the effects of interferon therapy on the oral health of veterans with HCV. This study was designed to determine if veterans with HCV undergoing 6 months of interferon therapy: (1) experience deterioration of their oral health compared to veterans with HCV not undergoing interferon therapy; (2) have decreased saliva flow (xerostomia); (3) and experience comparable oral health related quality of life (QOL) to veterans with HCV. If it is found that there is deterioration in the oral health in veterans with HCV undergoing interferon therapy then future studies will investigate possible interventions to prevent or minimize these changes.
Methods: This prospective cohort study will investigate group differences in the primary outcome (oral health) and secondary outcomes (xerostomia and QOL) between two groups over a period of 6 months. Twenty veterans with HCV undergoing interferon therapy and twenty veterans with HCV not undergoing interferon therapy will be enrolled. After informed consent is obtained participants will receive a comprehensive oral evaluation at the Portland VA Medical Center dental clinic. This evaluation will include a panoramic radiograph, periodontal charting, and evaluation for carious surfaces on teeth. Resting and stimulated salivary flow rates will be measured to determine the presence of xerostomia. Lastly, participants will complete the Oral Health Impact Profile (OHIP-14) as a measure of oral health QOL. After 24 weeks participants will return to the dental clinic and the study protocol will be repeated (dental exam, resting and stimulated saliva flow rate, and OHIP-14).
Results: Study in progress.
Repository Posting Date:
28-Oct-2011
Date of Publication:
28-Oct-2011
Conference Date:
2009
Conference Name:
6th Annual Florida Magnet Research Conference
Conference Host:
University of South Florida College of Nursing; Magnet Hospitals of Florida; Sigma Theta Tau International; Florida Organization of Nurse Executives
Conference Location:
Kissimmee, Florida
Description:
6th Annual Florida Magnet Research Conference � Theme: Research at the Point of Care. Held 12-13 February 2009 at Gaylord Palms Resort and Convention Center, Kissimmee, Florida, USA.
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_US
dc.typePresentationen_GB
dc.titleDoes Interferon Therapy Impact the Oral Health of Veterans with Hepatitis C?en_GB
dc.contributor.authorTaylor-Young, Pattyen_US
dc.contributor.authorZucker, Betsyen_US
dc.contributor.authorMcKeown, Seanen_US
dc.contributor.authorChang, Michaelen_US
dc.contributor.authorSasaki, Annaen_US
dc.author.detailsPatty Taylor-Young, PhD, RN,FNP, Portland VA Medical Center, Portland, OR, email: patricia.taylor-young@va.gov; Betsy Zucker, NP; Sean McKeown, DDS; Michael Chang, MD; Anna Sasaki, MD, PhDen_US
dc.identifier.urihttp://hdl.handle.net/10755/183108-
dc.description.abstractPurpose: Anecdotal evidence from experience clinicians suggests that oral health problems occur in veterans undergoing interferon therapy for hepatitis C (HCV). However, there has been no prospective investigation of this association. <br/>This study will expand knowledge regarding the oral health of veterans with HCV and provide new knowledge regarding the effects of interferon therapy on the oral health of veterans with HCV. This study was designed to determine if veterans with HCV undergoing 6 months of interferon therapy: (1) experience deterioration of their oral health compared to veterans with HCV not undergoing interferon therapy; (2) have decreased saliva flow (xerostomia); (3) and experience comparable oral health related quality of life (QOL) to veterans with HCV. If it is found that there is deterioration in the oral health in veterans with HCV undergoing interferon therapy then future studies will investigate possible interventions to prevent or minimize these changes.<br/>Methods: This prospective cohort study will investigate group differences in the primary outcome (oral health) and secondary outcomes (xerostomia and QOL) between two groups over a period of 6 months. Twenty veterans with HCV undergoing interferon therapy and twenty veterans with HCV not undergoing interferon therapy will be enrolled. After informed consent is obtained participants will receive a comprehensive oral evaluation at the Portland VA Medical Center dental clinic. This evaluation will include a panoramic radiograph, periodontal charting, and evaluation for carious surfaces on teeth. Resting and stimulated salivary flow rates will be measured to determine the presence of xerostomia. Lastly, participants will complete the Oral Health Impact Profile (OHIP-14) as a measure of oral health QOL. After 24 weeks participants will return to the dental clinic and the study protocol will be repeated (dental exam, resting and stimulated saliva flow rate, and OHIP-14). <br/>Results: Study in progress.en_GB
dc.date.available2011-10-28T16:14:53Z-
dc.date.issued2011-10-28en_GB
dc.date.accessioned2011-10-28T16:14:53Z-
dc.conference.date2009en_US
dc.conference.name6th Annual Florida Magnet Research Conferenceen_US
dc.conference.hostUniversity of South Florida College of Nursingen_US
dc.conference.hostMagnet Hospitals of Floridaen_US
dc.conference.hostSigma Theta Tau Internationalen_US
dc.conference.hostFlorida Organization of Nurse Executivesen_US
dc.conference.locationKissimmee, Floridaen_US
dc.description6th Annual Florida Magnet Research Conference � Theme: Research at the Point of Care. Held 12-13 February 2009 at Gaylord Palms Resort and Convention Center, Kissimmee, Florida, USA.en_US
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item. If a citation is listed in this record, the item has been published and is available via open-access avenues or a journal/database subscription. Contact your library for assistance in obtaining the as-published article.-
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