Development of a Self-Report Instrument to Evaluate the Cumulative Effect of Documented Risks, Triggers, and Protective Factors in Ovarian Cancer Expression

2.50
Hdl Handle:
http://hdl.handle.net/10755/201581
Type:
Presentation
Title:
Development of a Self-Report Instrument to Evaluate the Cumulative Effect of Documented Risks, Triggers, and Protective Factors in Ovarian Cancer Expression
Abstract:
(41st Biennial Convention) Introduction: Ovarian cancer is the most lethal of the gynecologic malignancies.  Early recognition is contingent upon the woman’s awareness of bodily changes and knowledge of risk factors that predispose her to this disease. It is the accumulation of several factors over time that leads to the expression of ovarian cancer. Worldwide, 300,000 women are diagnosed with ovarian cancer annually, the greatest incidence in the US and Europe, and lowest incidence in Africa and Asia.  Objectives: • Develop a self-report scale to assess the cumulative effect of multiple causative and protective factors leading to ovarian cancer • Establish content and construct validity of the instrument   • Establish reliability of the instrument Method/Procedure for tool development:  Due to non-availability of a relevant, multifaceted and comprehensive measure for examining multiple causative and protective factors leading to ovarian cancer, a self-report instrument is being developed based on a comprehensive literature review. Content and construct validity will be determined by factor analysis and expert review before being pilot tested. Statistical properties of each item will be determined and the items revised or deleted based on the empirical data.  Reliability will be determined by retesting. Results: Risks include: genetic factors; family or personal history of ovarian, breast, or colon cancer; aging; hormonal factors including early puberty, late menopause, nulliparity, infertility, and estrogen replacement therapy; obesity and dietary patterns; environmental/occupational exposure to pesticides, chemicals, asbestos, diesel fumes, and talcum powder; lifestyle factors of inactivity, alcohol use, smoking, and sexual orientation. Protective factors identified include use of contraception, breastfeeding, pregnancy, diet and exercise, certain medications, and specific menstrual cycle characteristics. Discussion & Conclusions: Instrument development will provide a means to investigate the multifaceted nature of the risks and protective factors related to ovarian cancer. Until a physiologically-based population screening test is developed, healthcare providers need more information about the combination of factors predisposing women to this deadly disease.
Keywords:
instrument development; ovarian cancer
Repository Posting Date:
11-Jan-2012
Date of Publication:
4-Jan-2012
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleDevelopment of a Self-Report Instrument to Evaluate the Cumulative Effect of Documented Risks, Triggers, and Protective Factors in Ovarian Cancer Expressionen_GB
dc.identifier.urihttp://hdl.handle.net/10755/201581-
dc.description.abstract(41st Biennial Convention) Introduction: Ovarian cancer is the most lethal of the gynecologic malignancies.  Early recognition is contingent upon the woman’s awareness of bodily changes and knowledge of risk factors that predispose her to this disease. It is the accumulation of several factors over time that leads to the expression of ovarian cancer. Worldwide, 300,000 women are diagnosed with ovarian cancer annually, the greatest incidence in the US and Europe, and lowest incidence in Africa and Asia.  Objectives: • Develop a self-report scale to assess the cumulative effect of multiple causative and protective factors leading to ovarian cancer • Establish content and construct validity of the instrument   • Establish reliability of the instrument Method/Procedure for tool development:  Due to non-availability of a relevant, multifaceted and comprehensive measure for examining multiple causative and protective factors leading to ovarian cancer, a self-report instrument is being developed based on a comprehensive literature review. Content and construct validity will be determined by factor analysis and expert review before being pilot tested. Statistical properties of each item will be determined and the items revised or deleted based on the empirical data.  Reliability will be determined by retesting. Results: Risks include: genetic factors; family or personal history of ovarian, breast, or colon cancer; aging; hormonal factors including early puberty, late menopause, nulliparity, infertility, and estrogen replacement therapy; obesity and dietary patterns; environmental/occupational exposure to pesticides, chemicals, asbestos, diesel fumes, and talcum powder; lifestyle factors of inactivity, alcohol use, smoking, and sexual orientation. Protective factors identified include use of contraception, breastfeeding, pregnancy, diet and exercise, certain medications, and specific menstrual cycle characteristics. Discussion & Conclusions: Instrument development will provide a means to investigate the multifaceted nature of the risks and protective factors related to ovarian cancer. Until a physiologically-based population screening test is developed, healthcare providers need more information about the combination of factors predisposing women to this deadly disease.en_GB
dc.subjectinstrument developmenten_GB
dc.subjectovarian canceren_GB
dc.date.available2012-01-11T10:41:22Z-
dc.date.issued2012-01-04en_GB
dc.date.accessioned2012-01-11T10:41:22Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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