Measurement Issues in the Study of Risk Factors for Deficits in Cognitive Function Related to Chemotherapy

2.50
Hdl Handle:
http://hdl.handle.net/10755/201836
Type:
Presentation
Title:
Measurement Issues in the Study of Risk Factors for Deficits in Cognitive Function Related to Chemotherapy
Abstract:
(41st Biennial Convention) The goal of this presentation is to identify and propose solutions for many of the measurement issues involved in biopsychosocial research. Examples from current a current study of problems with cognitive function (CF) in women receiving chemotherapy for breast cancer (BC) are used. Identified methodological problems in this study include lack of a common definition of CF in this population, lack of pretreatment data, and potential confounds.  The specific aims of this presentation are to identify, describe and suggest solutions for a variety of issues to include:  1.) The objective measurement of cognition and cognitive changes in cancer patients.  How to adapt neuropsychological assessment, designed as a clinical tool for comparison between a patient’s current level of functioning and the known or estimated level of premobid functioning according to demographic “norms,” to a repeated measurement research tool sensitive to change in function in a high-functioning population of women with BC? How to address problems of practice effect and measurement bias?  2.) The differences between objective and subjective measurement. Research suggests that subjective report is not correlated with objective measures of cognitive problems and that subjective report of cognitive problems is related to depression and anxiety; 3) The control of covariability.   Categorically, biopsychosocial research problems such as the one described here involve complex variability; and 4.) The study of psychosocial factors affecting cognition and cognitive changes in cancer patients receiving CTX. Choice of instrumentation for the study is based on specificity to the research question, psychometric properties (specifically in BC), ease of completion, sensitivity to change over time. Measures must be stable enough to detect change over time while discriminating from other responses. Potential confounds exist in the measurement of many variables so the ability of an instrument to distinguish among concepts is an important part of validity.
Keywords:
biopsychosocial variability; research design; neuropsychological measures
Repository Posting Date:
11-Jan-2012
Date of Publication:
4-Jan-2012
Sponsors:
Sigma Theta Tau International

Full metadata record

DC FieldValue Language
dc.typePresentationen_GB
dc.titleMeasurement Issues in the Study of Risk Factors for Deficits in Cognitive Function Related to Chemotherapyen_GB
dc.identifier.urihttp://hdl.handle.net/10755/201836-
dc.description.abstract(41st Biennial Convention) The goal of this presentation is to identify and propose solutions for many of the measurement issues involved in biopsychosocial research. Examples from current a current study of problems with cognitive function (CF) in women receiving chemotherapy for breast cancer (BC) are used. Identified methodological problems in this study include lack of a common definition of CF in this population, lack of pretreatment data, and potential confounds.  The specific aims of this presentation are to identify, describe and suggest solutions for a variety of issues to include:  1.) The objective measurement of cognition and cognitive changes in cancer patients.  How to adapt neuropsychological assessment, designed as a clinical tool for comparison between a patient’s current level of functioning and the known or estimated level of premobid functioning according to demographic “norms,” to a repeated measurement research tool sensitive to change in function in a high-functioning population of women with BC? How to address problems of practice effect and measurement bias?  2.) The differences between objective and subjective measurement. Research suggests that subjective report is not correlated with objective measures of cognitive problems and that subjective report of cognitive problems is related to depression and anxiety; 3) The control of covariability.   Categorically, biopsychosocial research problems such as the one described here involve complex variability; and 4.) The study of psychosocial factors affecting cognition and cognitive changes in cancer patients receiving CTX. Choice of instrumentation for the study is based on specificity to the research question, psychometric properties (specifically in BC), ease of completion, sensitivity to change over time. Measures must be stable enough to detect change over time while discriminating from other responses. Potential confounds exist in the measurement of many variables so the ability of an instrument to distinguish among concepts is an important part of validity.en_GB
dc.subjectbiopsychosocial variabilityen_GB
dc.subjectresearch designen_GB
dc.subjectneuropsychological measuresen_GB
dc.date.available2012-01-11T10:55:33Z-
dc.date.issued2012-01-04en_GB
dc.date.accessioned2012-01-11T10:55:33Z-
dc.description.sponsorshipSigma Theta Tau Internationalen_GB
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