2.50
Hdl Handle:
http://hdl.handle.net/10755/211544
Type:
Research Study
Title:
PREVALENCE AND CORRELATES OF SUICIDE IDEATION IN PATIENTS WITH COPD
Abstract:
Background: Depression in patients with chronic obstructive pulmonary disease (COPD) is associated with worse clinical and functional outcomes.  However, very little research has been done on suicide ideation (SI) and its correlates in this population.  The aim of this analysis is to examine the prevalence of SI and its correlates in patients with stable moderate to very severe COPD. Methods: This is an exploratory analysis from an ongoing longitudinal observational study of the biological causes and functional consequences of depression in patients with COPD.  We measured depression and SI using the Personal Health Questionnaire (PHQ-9) at study entry. Correlates included demographic characteristics, disease severity, time since COPD diagnosis, scores on the Hospital Anxiety and Depression Questionnaire (HADS), history of depression, current treatments for depression and anxiety, smoking status, alcohol use, and performance on a six minute walk test.  Independent t-tests and chi-square tests were used to compare differences between patients endorsing SI versus not. Results: The characteristics of the 117 participants were: mean age of 68 ± 9;, 22% females, and forced expiratory volume in 1 second (FEV1) % predicted of 41.5 ± 15%. The prevalence of SI was 10%. Patients who endorsed SI were significantly more likely to be females, have better lung function (FEV1 % predicted of 40 vs. 49%, p=.07), lived with COPD for a longer time, have a household income less than 20K/year, had a history of depression prior to being diagnosed with COPD (p=.09), have higher PHQ-9 and HADS scores, be on an antidepressant, and received mental health counseling (all p<.05 unless otherwise noted); however, they were no more likely to have a history of heavy drinking, be current smokers or taking anxiolytics, and were of similar age and physical functioning compared to patients who did not endorse SI. Implications:  We found that the prevalence of SI in patients with stable moderate to severe COPD falls within the wide range of SI prevalence estimated from population-based surveys across 9 countries, 2-19% (Weissman et al, Psych Med, 1999, 29(1):9-17). Patients who endorse SI experience severe depression and anxiety that may be due to the burden of COPD and economic hardship, and may need better treatment optimization. A major limitation of this analysis is the use of a convenience, non-representative sample.
Keywords:
COPD; Chronic obstructive pulmonary disease; Depression
Repository Posting Date:
20-Feb-2012
Date of Publication:
20-Feb-2012
Other Identifiers:
5416
Sponsors:
Western Institute of Nursing

Full metadata record

DC FieldValue Language
dc.typeResearch Studyen_GB
dc.titlePREVALENCE AND CORRELATES OF SUICIDE IDEATION IN PATIENTS WITH COPDen_GB
dc.identifier.urihttp://hdl.handle.net/10755/211544-
dc.description.abstractBackground: Depression in patients with chronic obstructive pulmonary disease (COPD) is associated with worse clinical and functional outcomes.  However, very little research has been done on suicide ideation (SI) and its correlates in this population.  The aim of this analysis is to examine the prevalence of SI and its correlates in patients with stable moderate to very severe COPD. Methods: This is an exploratory analysis from an ongoing longitudinal observational study of the biological causes and functional consequences of depression in patients with COPD.  We measured depression and SI using the Personal Health Questionnaire (PHQ-9) at study entry. Correlates included demographic characteristics, disease severity, time since COPD diagnosis, scores on the Hospital Anxiety and Depression Questionnaire (HADS), history of depression, current treatments for depression and anxiety, smoking status, alcohol use, and performance on a six minute walk test.  Independent t-tests and chi-square tests were used to compare differences between patients endorsing SI versus not. Results: The characteristics of the 117 participants were: mean age of 68 ± 9;, 22% females, and forced expiratory volume in 1 second (FEV1) % predicted of 41.5 ± 15%. The prevalence of SI was 10%. Patients who endorsed SI were significantly more likely to be females, have better lung function (FEV1 % predicted of 40 vs. 49%, p=.07), lived with COPD for a longer time, have a household income less than 20K/year, had a history of depression prior to being diagnosed with COPD (p=.09), have higher PHQ-9 and HADS scores, be on an antidepressant, and received mental health counseling (all p<.05 unless otherwise noted); however, they were no more likely to have a history of heavy drinking, be current smokers or taking anxiolytics, and were of similar age and physical functioning compared to patients who did not endorse SI. Implications:  We found that the prevalence of SI in patients with stable moderate to severe COPD falls within the wide range of SI prevalence estimated from population-based surveys across 9 countries, 2-19% (Weissman et al, Psych Med, 1999, 29(1):9-17). Patients who endorse SI experience severe depression and anxiety that may be due to the burden of COPD and economic hardship, and may need better treatment optimization. A major limitation of this analysis is the use of a convenience, non-representative sample.en_GB
dc.subjectCOPDen_GB
dc.subjectChronic obstructive pulmonary diseaseen_GB
dc.subjectDepressionen_GB
dc.date.available2012-02-20T12:01:23Z-
dc.date.issued2012-02-20T12:01:23Z-
dc.date.accessioned2012-02-20T12:01:23Z-
dc.description.sponsorshipWestern Institute of Nursingen_GB
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