State of the Science: Symptoms and Quality of Life in Individuals with Pancreatic Cancer Undergoing Surgery

2.50
Hdl Handle:
http://hdl.handle.net/10755/243381
Category:
Full-text
Type:
Presentation
Title:
State of the Science: Symptoms and Quality of Life in Individuals with Pancreatic Cancer Undergoing Surgery
Author(s):
Burrell, Sherry A.; Yeo, Theresa Pluth; Smeltzer, Suzanne C.
Lead Author STTI Affiliation:
Delta Rho
Author Details:
Burrell, Sherry A., MSN, RN, ACNS-BC, CNE, sherryb@camden.rutgers.edu; Yeo, Theresa Pluth, PhD, MPH, MSN; Smeltzer, Suzanne C., EdD, RN, MS, FAAN;
Abstract:
Purpose:   The purpose of this integrative review was to examine the science regarding symptoms and quality of life (QoL) in individuals with pancreatic cancer (PC) undergoing surgery with or without adjuvant therapy.

Methods: The integrative review method was used to conduct this review of the literature. Whittemore and Knafl’s (2005) updated integrative review guidelines were followed.  Fourteen studies were included for review as a result of a search in Medline, PubMED, and CINAHL databases from 1995 to 2012.

Results: Several studies had methodological issues including poor response rates, small sample sizes, and heterogeneous samples that limited the generalizability of results and failed to provide a full picture of symptoms and QoL in individuals with PC after surgery with or without adjuvant therapy.   Nonetheless, studies revealed the occurrence of foul stools, flatus, thirst, frequent urination, diabetes mellitus, heartburn, nausea, vomiting, weight loss, abdominal pain, fatigue, and muscle weakness were major symptom concerns in this population.  In several studies, individuals with PC were found to experience significantly higher symptom severity when compared to individuals with benign pancreas conditions.  More than 70% of studies that concurrently examined symptoms revealed that overall QoL or one or more domains of QoL were significantly impaired.  Thus, suggesting that multiple symptoms may have a negative impact on QoL in this population.

Conclusions:   Individuals with PC undergoing surgery with or without adjuvant therapy experience multiple symptoms that may have a negative impact on QoL.  Methodological concerns were apparent in the previous research; thus, future research should include homogenous samples to improve the generalizability of findings and be conducted longitudinally to capture changes in symptoms and QoL over time. It is clear that additional research is needed to fully understand symptoms, the factors that influence symptoms, and the direct impact that symptoms have on QoL in this population.

Keywords:
Pancreatic Cancer; Symptoms and Quality of Life; Integrative Review of the Literature
Repository Posting Date:
12-Sep-2012
Date of Publication:
12-Sep-2012 ; 12-Sep-2012
Conference Date:
2012
Conference Name:
23rd International Nursing Research Congress
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Brisbane, Australia

Full metadata record

DC FieldValue Language
dc.language.isoenen
dc.type.categoryFull-texten
dc.typePresentationen
dc.titleState of the Science: Symptoms and Quality of Life in Individuals with Pancreatic Cancer Undergoing Surgeryen
dc.contributor.authorBurrell, Sherry A.en
dc.contributor.authorYeo, Theresa Pluthen
dc.contributor.authorSmeltzer, Suzanne C.en
dc.contributor.departmentDelta Rhoen
dc.author.detailsBurrell, Sherry A., MSN, RN, ACNS-BC, CNE, sherryb@camden.rutgers.edu; Yeo, Theresa Pluth, PhD, MPH, MSN; Smeltzer, Suzanne C., EdD, RN, MS, FAAN;en
dc.identifier.urihttp://hdl.handle.net/10755/243381-
dc.description.abstract<b><b>Purpose: </b></b>&nbsp; The purpose of this integrative review was to examine the science regarding symptoms and quality of life (QoL) in individuals with pancreatic cancer (PC) undergoing surgery with or without adjuvant therapy. <p><b><b>Methods: </b> </b>The integrative review method was used to conduct this review of the literature. Whittemore and Knafl&rsquo;s (2005) updated integrative review guidelines were followed.&nbsp; Fourteen studies were included for review as a result of a search in Medline, PubMED, and CINAHL databases from 1995 to 2012.<b></b><p><b><b>Results: </b> </b>Several studies had methodological issues including poor response rates, small sample sizes, and heterogeneous samples that limited the generalizability of results and failed to provide a full picture of symptoms and QoL in individuals with PC after surgery with or without adjuvant therapy.&nbsp; &nbsp;Nonetheless, studies revealed the occurrence of foul stools, flatus, thirst, frequent urination, diabetes mellitus, heartburn, nausea, vomiting, weight loss, abdominal pain, fatigue, and muscle weakness were major symptom concerns in this population.<sup> </sup>&nbsp;In several studies, individuals with PC were found to experience significantly higher symptom severity when compared to individuals with benign pancreas conditions. &nbsp;More than 70% of studies that concurrently examined symptoms revealed that overall QoL or one or more domains of QoL were significantly impaired.&nbsp; Thus, suggesting that multiple symptoms may have a negative impact on QoL in this population. <p><b><b>Conclusions: </b></b>&nbsp; Individuals with PC undergoing surgery with or without adjuvant therapy experience multiple symptoms that may have a negative impact on QoL.&nbsp; Methodological concerns were apparent in the previous research; thus, future research should include homogenous samples to improve the generalizability of findings and be conducted longitudinally to capture changes in symptoms and QoL over time. It is clear that additional research is needed to fully understand symptoms, the factors that influence symptoms, and the direct impact that symptoms have on QoL in this population.en
dc.subjectPancreatic Canceren
dc.subjectSymptoms and Quality of Lifeen
dc.subjectIntegrative Review of the Literatureen
dc.date.available2012-09-12T09:21:27Z-
dc.date.issued2012-09-12-
dc.date.issued2012-09-12en
dc.date.accessioned2012-09-12T09:21:27Z-
dc.conference.date2012en
dc.conference.name23rd International Nursing Research Congressen
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen
dc.conference.locationBrisbane, Australiaen
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