Sleep Patterns and Nocturnal Disturbances in Hospitalized Hematopoietic Stem Cell Transplant Patients

2.50
Hdl Handle:
http://hdl.handle.net/10755/243415
Category:
Abstract
Type:
Presentation
Title:
Sleep Patterns and Nocturnal Disturbances in Hospitalized Hematopoietic Stem Cell Transplant Patients
Author(s):
Hacker, Eileen Danaher; Stainthorpe, Megan; Larson, Janet L.; Ferrans, Carol Estwing; Patel, Purvi
Author Details:
Hacker, Eileen Danaher, PhD, APN, AOCN, ehacker@uic.edu; Stainthorpe, MeganLarson, Janet L., RN, PhD, FAAN; Ferrans, Carol Estwing, PhD, RN, FAAN; Patel, Purvi;
Abstract:
Purpose: People receiving high-dose chemotherapy followed by hematopoietic stem cell transplantation (HSCT) frequently report sleep disturbances during the acute phase of treatment although objective documentation of this is lacking.  This study employed subjective and objective sleep assessments to evaluate sleep patterns and examine relationships among sleep patterns, quality of life, and demographic factors.

Methods: The convenience sample consisted of 40 hospitalized HSCT patients.  Each subject wore a wrist actigraph for five days to assess sleep patterns and completed a quality of life questionnaire that included a sleep disturbance item (EORTC QLQ C-30).  The medical record was retrospectively reviewed to determine the number and type of nocturnal disturbances.

Results: Results indicate there is a high prevalence of sleep disturbances during hospitalization following HSCT. Most subjects (n=82%) reported some sleep disturbance.  The mean total sleep time per 24-hour period was 5:41 hours and sleep efficiency, 55%.  Thirty-five percent of subjects did not experience a major sleep interval (lasting more than 3 hours) during one or more 24-hour period.  Subjects older than 60 spent more time attempting to fall asleep compared to those between 18 and 39 (p< .05). The most common nocturnal disturbance was medication administration. Total sleep time was moderately correlated with pain (r=.363, p< .05) and dyspnea (r =.372, p< .05). Subjective assessment of sleep negatively correlated with age (r= -.375, p< .05) and cognitive function (r= -.380, p< .05) while positively correlated with pain (r= .327, p< .05).

Conclusion: Findings suggest that a substantial number of HSCT patients experience sleep disturbances during the acute phase of HSCT treatment. Reductions in total sleep time were associated with increased pain and dyspnea.  As sleep is an essential biological function, additional research is needed regarding the effects of sleep disturbances on recovery following HSCT and interventions to optimize sleep during hospitalization.

Keywords:
sleep disturbances; hematopoietic stem cell transplantation; quality of life
Repository Posting Date:
12-Sep-2012
Date of Publication:
12-Sep-2012
Conference Date:
2012
Conference Name:
23rd International Nursing Research Congress
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Brisbane, Australia

Full metadata record

DC FieldValue Language
dc.type.categoryAbstracten_GB
dc.typePresentationen_GB
dc.titleSleep Patterns and Nocturnal Disturbances in Hospitalized Hematopoietic Stem Cell Transplant Patientsen_GB
dc.contributor.authorHacker, Eileen Danaheren_GB
dc.contributor.authorStainthorpe, Meganen_GB
dc.contributor.authorLarson, Janet L.en_GB
dc.contributor.authorFerrans, Carol Estwingen_GB
dc.contributor.authorPatel, Purvien_GB
dc.author.detailsHacker, Eileen Danaher, PhD, APN, AOCN, ehacker@uic.edu; Stainthorpe, MeganLarson, Janet L., RN, PhD, FAAN; Ferrans, Carol Estwing, PhD, RN, FAAN; Patel, Purvi;en_GB
dc.identifier.urihttp://hdl.handle.net/10755/243415-
dc.description.abstract<b>Purpose: </b> People receiving high-dose chemotherapy followed by hematopoietic stem cell transplantation (HSCT) frequently report sleep disturbances during the acute phase of treatment although objective documentation of this is lacking.&nbsp; This study employed subjective and objective sleep assessments to evaluate sleep patterns and examine relationships among sleep patterns, quality of life, and demographic factors. <p><b>Methods: </b> The convenience sample consisted of 40 hospitalized HSCT patients. &nbsp;Each subject wore a wrist actigraph for five days to assess sleep patterns and completed a quality of life questionnaire that included a sleep disturbance item (EORTC QLQ C-30). &nbsp;The medical record was retrospectively reviewed to determine the number and type of nocturnal disturbances. <p><b>Results: </b> Results indicate there is a high prevalence of sleep disturbances during hospitalization following HSCT. Most subjects (n=82%) reported some sleep disturbance. &nbsp;The mean total sleep time per 24-hour period was 5:41 hours and sleep efficiency, 55%.&nbsp; Thirty-five percent of subjects did not experience a major sleep interval (lasting more than 3 hours) during one or more 24-hour period.&nbsp; Subjects older than 60 spent more time attempting to fall asleep compared to those between 18 and 39 (p&lt; .05). The most common nocturnal disturbance was medication administration. Total sleep time was moderately correlated with pain (r=.363, p&lt; .05) and dyspnea (r =.372, p&lt; .05). Subjective assessment of sleep negatively correlated with age (r= -.375, p&lt; .05) and cognitive function (r= -.380, p&lt; .05) while positively correlated with pain (r= .327, p&lt; .05). <p><b>Conclusion: </b> Findings suggest that a substantial number of HSCT patients experience sleep disturbances during the acute phase of HSCT treatment. Reductions in total sleep time were associated with increased pain and dyspnea. &nbsp;As sleep is an essential biological function, additional research is needed regarding the effects of sleep disturbances on recovery following HSCT and interventions to optimize sleep during hospitalization.en_GB
dc.subjectsleep disturbancesen_GB
dc.subjecthematopoietic stem cell transplantationen_GB
dc.subjectquality of lifeen_GB
dc.date.available2012-09-12T09:21:56Z-
dc.date.issued2012-09-12-
dc.date.accessioned2012-09-12T09:21:56Z-
dc.conference.date2012en_GB
dc.conference.name23rd International Nursing Research Congressen_GB
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen_GB
dc.conference.locationBrisbane, Australiaen_GB
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