A Pilot Intervention to Improve Medication Adherence in Nonadherenct Inflammatory Bowel Disease Patients

2.50
Hdl Handle:
http://hdl.handle.net/10755/244051
Category:
Abstract
Type:
Research Study
Title:
A Pilot Intervention to Improve Medication Adherence in Nonadherenct Inflammatory Bowel Disease Patients
Author(s):
Matteson, Michelle L.; Russell, Cynthia L.
Lead Author STTI Affiliation:
Alpha Iota
Author Details:
Michelle L. Matteson RN, CS, FNP/GNP, PhD (c) (corresponding author) Doctoral Student Sinclair School of Nursing University of Missouri One Hospital Drive, DC 0043.00 Columbia, MO 65212 (573) 884-7600 work; (573) 884-8200 Fax mattesonml@health.missouri.edu Cynthia L. Russell, RN, PhD, ACNS-BC, FAAN Associate Professor Sinclair School of Nursing University of Missouri Columbia, MO 65211 (573) 884-9541 work; (573) 884-4544 fax RussellC@missouri.edu
Abstract:

A PILOT INTERVENTION TO IMPROVE MEDICATION ADHERENCE IN NONADHERENCT INFLAMMATORY BOWEL DISEASE PATIENTS

Michelle L. Matteson

Dr. Cynthia Russell, Dissertation Supervisor

Abstract

 

Background: Medication nonadherence in inflammatory bowel disease (IBD) can lead to suboptimal control of the disease, decreased quality of life, and poorer outcomes. This pilot study evaluated the feasibility, intervention mechanism, and potential effectiveness of a three-month continuous self-improvement (CSI) intervention to enhance medication adherence in adult nonadherent IBD patients.

Methods: Adult IBD patients taking a daily or twice-daily dosed maintenance medication were screened for two months to determine baseline medication adherence levels. Adherence was monitored electronically. Nonadherent IBD participants were randomized to receive either the CSI intervention or the attention control intervention and then monitored for three-months. The CSI intervention consisted of a data evaluation and system refinement process in which personal system changes were identified and implemented. The attention control group was given only educational information regarding IBD disease process, extra-intestinal manifestations of IBD, and medical therapy actions and side effects. Demographic statistics, change scores for within and between-group differences, and effect size estimates were calculated. 

Results: Nine nonadherent participants (medication adherence score   System thinking scores trended in the anticipated direction.  Although no statistically significant improvement in medication adherence was found (p=0.14), medication adherence improved in 3 of 4 of the CSI group and only 1 of 2 in the attention control group. The effect size calculation of 1.9 will determine the sample size for future study.

Conclusions: The results of this pilot study showed the intervention was feasible and had a positive effect on the medication adherence change score and on adherence levels. A larger fully powered study is needed to test of the effectiveness of this innovative intervention.

Keywords:
adherence; inflammatory bowel diseases psychology; intervention
Repository Posting Date:
14-Sep-2012
Date of Publication:
2011
Citation:
Matteson, M. (2011). A pilot intervention to improve medication adherence in nonadherent inflammatory bowel disease patients. University of Missouri - Columbia). ProQuest Dissertations and Theses, Retrieved from http://search.proquest.com/docview/1018400874?accountid=14576. (1018400874).
Publisher:
ProQuest #1018400874
Sponsors:
Sigma Theta Tau International
Note:
The Sigma Theta Tau International grant application that funded this research, in whole or in part, was completed by the applicant and peer-reviewed prior to the award of the STTI grant. No further peer-review has taken place upon the completion of the STTI grant final report and its appearance in this repository.; This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen
dc.type.categoryAbstracten
dc.typeResearch Studyen
dc.titleA Pilot Intervention to Improve Medication Adherence in Nonadherenct Inflammatory Bowel Disease Patientsen_US
dc.contributor.authorMatteson, Michelle L.-
dc.contributor.authorRussell, Cynthia L.-
dc.contributor.departmentAlpha Iotaen
dc.author.detailsMichelle L. Matteson RN, CS, FNP/GNP, PhD (c) (corresponding author) Doctoral Student Sinclair School of Nursing University of Missouri One Hospital Drive, DC 0043.00 Columbia, MO 65212 (573) 884-7600 work; (573) 884-8200 Fax mattesonml@health.missouri.edu Cynthia L. Russell, RN, PhD, ACNS-BC, FAAN Associate Professor Sinclair School of Nursing University of Missouri Columbia, MO 65211 (573) 884-9541 work; (573) 884-4544 fax RussellC@missouri.eduen
dc.identifier.urihttp://hdl.handle.net/10755/244051-
dc.description.abstract<p class="MsoListParagraph" style="margin: 0in 0in 0pt; line-height: 200%; text-autospace: ideograph-numeric; text-align: center; mso-margin-top-alt: auto;" align="center"><span style="font-size: small; font-family: Times New Roman;">A PILOT INTERVENTION TO IMPROVE MEDICATION ADHERENCE IN NONADHERENCT INFLAMMATORY BOWEL DISEASE PATIENTS </span></p> <p class="MsoListParagraph" style="margin: 0in 0in 0pt; line-height: 200%; text-autospace: ideograph-numeric; text-align: center; mso-margin-top-alt: auto;" align="center"><span style="font-size: small; font-family: Times New Roman;">Michelle L. Matteson</span></p> <p class="MsoListParagraph" style="margin: 0in 0in 0pt; line-height: 200%; text-autospace: ideograph-numeric; text-align: center; mso-margin-top-alt: auto;" align="center"><span style="font-size: small; font-family: Times New Roman;">Dr. Cynthia Russell, Dissertation Supervisor</span></p> <p class="MsoNormal" style="margin: 0in 0in 0pt; text-align: center;" align="center"><span style="font-size: small; font-family: Times New Roman;">Abstract</span></p> <p class="MsoNormal" style="margin: 0in 0in 0pt; text-align: center;" align="center"><span style="font-size: small; font-family: Times New Roman;"> </span></p> <p class="MsoNormal" style="margin: 0in 0in 0pt; line-height: 200%;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong style="mso-bidi-font-weight: normal;">Background:</strong> Medication nonadherence in inflammatory bowel disease (IBD) can lead to suboptimal control of the disease, decreased quality of life, and poorer outcomes. This pilot study evaluated the feasibility, intervention mechanism, and potential effectiveness of a three-month continuous self-improvement (CSI) intervention to enhance medication adherence in adult nonadherent IBD patients.</span></span></p> <p class="MsoNormal" style="margin: 0in 0in 0pt; line-height: 200%;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong style="mso-bidi-font-weight: normal;">Methods:</strong> Adult IBD patients taking a daily or twice-daily dosed maintenance medication were screened for two months to determine baseline medication adherence levels. Adherence was monitored electronically. Nonadherent IBD participants were randomized to receive either the CSI intervention or the attention control intervention and then monitored for three-months. The CSI intervention consisted of a data evaluation and system refinement process in which personal system changes were identified and implemented. The attention control group was given only educational information regarding IBD disease process, extra-intestinal manifestations of IBD, and medical therapy actions and side effects. Demographic statistics, change scores for within and between-group differences, and effect size estimates were calculated.<span style="mso-spacerun: yes;">  </span></span></span></p> <p class="MsoNormal" style="margin: 0in 0in 0pt; line-height: 200%;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong style="mso-bidi-font-weight: normal;">Results:</strong> Nine nonadherent participants (medication adherence score   </span>System thinking scores trended in the anticipated direction.<span style="mso-spacerun: yes;">  </span>Although no statistically significant improvement in medication adherence was found (p=0.14), medication adherence improved in 3 of 4 of the CSI group and only 1 of 2 in the attention control group. The effect size calculation of 1.9 will determine the sample size for future study.</span></p> <p class="MsoNormal" style="margin: 0in 0in 0pt; line-height: 200%;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><strong style="mso-bidi-font-weight: normal;">Conclusions:</strong> The results of this pilot study showed the intervention was feasible and had a positive effect on the medication adherence change score and on adherence levels. A larger fully powered study is needed to test of the effectiveness of this innovative intervention.</span></span></p>en_GB
dc.subjectadherenceen_GB
dc.subjectinflammatory bowel diseases psychologyen_GB
dc.subjectinterventionen_GB
dc.date.available2012-09-14T21:27:05Z-
dc.date.issued2011-
dc.date.accessioned2012-09-14T21:27:05Z-
dc.identifier.citationMatteson, M. (2011). A pilot intervention to improve medication adherence in nonadherent inflammatory bowel disease patients. University of Missouri - Columbia). ProQuest Dissertations and Theses, Retrieved from http://search.proquest.com/docview/1018400874?accountid=14576. (1018400874).en_GB
dc.publisherProQuest #1018400874en_GB
dc.identifier.isbn9.78127E+12-
dc.description.sponsorshipSigma Theta Tau Internationalen
dc.identifier.citationMatteson, M. (2011). A pilot intervention to improve medication adherence in nonadherent inflammatory bowel disease patients. University of Missouri - Columbia). ProQuest Dissertations and Theses, Retrieved from http://search.proquest.com/docview/1018400874?accountid=14576. (1018400874).en_GB
dc.description.noteThe Sigma Theta Tau International grant application that funded this research, in whole or in part, was completed by the applicant and peer-reviewed prior to the award of the STTI grant. No further peer-review has taken place upon the completion of the STTI grant final report and its appearance in this repository.en
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission. Alternatively, please contact the conference host, journal, or publisher (according to the circumstance) for further details regarding this item.-
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