Toward Therapeutics for Symptom Clusters During the Menopausal Transition and Early Postmenopause: A Systematic Review

2.50
Hdl Handle:
http://hdl.handle.net/10755/303986
Category:
Full-text
Type:
Presentation
Title:
Toward Therapeutics for Symptom Clusters During the Menopausal Transition and Early Postmenopause: A Systematic Review
Author(s):
Woods, Nancy Fugate; Thomas, Annette; Mitchell, Ellen Sullivan; Schnall, Janet; Taylor-Swanson, Lisa; Ismail, Rita; Cray, Lori
Lead Author STTI Affiliation:
Non-member
Author Details:
Nancy Fugate Woods, PhD, RN, FAAN, nfwoods@uw.edu; Annette Thomas, BSN; Ellen Sullivan Mitchell, RN, PhD; Janet Schnall, MS, AHIP; Lisa Taylor-Swanson, EAMP, BS, MS Dipl. OM (NCCAOM); Rita Ismail, BSN; Lori Cray, PhD, RN;
Abstract:

Session presented on: Tuesday, July 23, 2013

Purpose: Systematically review clinical trials of Traditional East Asian Medicine, herbals, soy and isoflavone preparations, and body-mind therapies for managing symptoms of hot flashes and at least one additional symptom, including mood, sleep, pain, and cognitive symptoms.

Methods: Searched PubMED/Medline, CINAHL Plus, PsycInfo, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Web of Science, EMBASE, AMED, and Alt-Health Watch for randomized controlled trials reported in English between 2004 and 2012. Of 1193 abstracts identified, 59 trials included data on hot flash and at least one other symptom

Results: Several trials of acupuncture (13), herbals including black cohosh (18), soy and isoflavone preparations (17), and body-mind therapies (9) yielded significant effects on multiple symptoms.' Seven acupuncture trials revealed significantly reduced hot flash frequency, intensity or bother, along with improved mood and sleep.' Chinese herbal medicine significantly reduced HF frequency, and mood, sleep, and pain. Four of 9 black cohosh trials significantly improved hot flashes, sleep and mood. ''Two trials of at least 60-70 mg of isoflavones daily significantly reduced vasomotor, sleep, cognitive and pain symptoms. Equol supplements of 30 mg/d for non-Equol producing women significantly reduced vasomotor, psychological and somatic symptoms. Two trials of Genistein preparations reduced hot flashes by 30-51% but not other symptoms. 'Red Clover isoflavone (80 mg/d) significantly reduced hot flashes, night sweats, sleep, cognition and pain symptoms. Mindfulness and relaxation therapy significantly reduced hot flashes and sleep symptoms. Yoga significantly reduced hot flashes and improved cognitive symptoms.' Exercise trials yielded mixed results, with half significantly reducing hot flashes and one cognitive symptoms.

Conclusion: Few investigators report treatment effects in ways that allow clinicians to consider symptom clusters when prescribing therapies, despite promising therapies

Keywords:
menopause; symptom clusters; complementary therapies
Repository Posting Date:
22-Oct-2013
Date of Publication:
22-Oct-2013 ; 22-Oct-2013
Conference Date:
2013
Conference Name:
24th International Nursing Research Congress
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Prague, Czech Republic
Description:
24th International Nursing Research Congress Theme: Bridge the Gap Between Research and Practice Through Collaboration. Held at the Hilton Prague Hotel.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_GB
dc.language.isoenen
dc.type.categoryFull-texten
dc.typePresentationen
dc.titleToward Therapeutics for Symptom Clusters During the Menopausal Transition and Early Postmenopause: A Systematic Reviewen
dc.contributor.authorWoods, Nancy Fugateen
dc.contributor.authorThomas, Annetteen
dc.contributor.authorMitchell, Ellen Sullivanen
dc.contributor.authorSchnall, Janeten
dc.contributor.authorTaylor-Swanson, Lisaen
dc.contributor.authorIsmail, Ritaen
dc.contributor.authorCray, Lorien
dc.contributor.departmentNon-memberen
dc.author.detailsNancy Fugate Woods, PhD, RN, FAAN, nfwoods@uw.edu; Annette Thomas, BSN; Ellen Sullivan Mitchell, RN, PhD; Janet Schnall, MS, AHIP; Lisa Taylor-Swanson, EAMP, BS, MS Dipl. OM (NCCAOM); Rita Ismail, BSN; Lori Cray, PhD, RN;en
dc.identifier.urihttp://hdl.handle.net/10755/303986-
dc.description.abstract<p>Session presented on: Tuesday, July 23, 2013</p><b>Purpose: </b> Systematically review clinical trials of Traditional East Asian Medicine, herbals, soy and isoflavone preparations, and body-mind therapies for managing symptoms of hot flashes and at least one additional symptom, including mood, sleep, pain, and cognitive symptoms. <p><b>Methods: </b> Searched PubMED/Medline, CINAHL Plus, PsycInfo, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Web of Science, EMBASE, AMED, and Alt-Health Watch for randomized controlled trials reported in English between 2004 and 2012. Of 1193 abstracts identified, 59 trials included data on hot flash and at least one other symptom <p><b>Results: </b> Several trials of acupuncture (13), herbals including black cohosh (18), soy and isoflavone preparations (17), and body-mind therapies (9) yielded significant effects on multiple symptoms.' Seven acupuncture trials revealed significantly reduced hot flash frequency, intensity or bother, along with improved mood and sleep.' Chinese herbal medicine significantly reduced HF frequency, and mood, sleep, and pain. Four of 9 black cohosh trials significantly improved hot flashes, sleep and mood. ''Two trials of at least 60-70 mg of isoflavones daily significantly reduced vasomotor, sleep, cognitive and pain symptoms. Equol supplements of 30 mg/d for non-Equol producing women significantly reduced vasomotor, psychological and somatic symptoms. Two trials of Genistein preparations reduced hot flashes by 30-51% but not other symptoms. 'Red Clover isoflavone (80 mg/d) significantly reduced hot flashes, night sweats, sleep, cognition and pain symptoms. Mindfulness and relaxation therapy significantly reduced hot flashes and sleep symptoms. Yoga significantly reduced hot flashes and improved cognitive symptoms.' Exercise trials yielded mixed results, with half significantly reducing hot flashes and one cognitive symptoms. <p><b>Conclusion: </b> Few investigators report treatment effects in ways that allow clinicians to consider symptom clusters when prescribing therapies, despite promising therapiesen
dc.subjectmenopauseen
dc.subjectsymptom clustersen
dc.subjectcomplementary therapiesen
dc.date.available2013-10-22T20:27:08Z-
dc.date.issued2013-10-22-
dc.date.issued2013-10-22en
dc.date.accessioned2013-10-22T20:27:08Z-
dc.conference.date2013en
dc.conference.name24th International Nursing Research Congressen
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen
dc.conference.locationPrague, Czech Republicen
dc.description24th International Nursing Research Congress Theme: Bridge the Gap Between Research and Practice Through Collaboration. Held at the Hilton Prague Hotel.en
All Items in this repository are protected by copyright, with all rights reserved, unless otherwise indicated.