Correlation of Patient Perception of Fatigue, Sleep Disturbance with Motivation and Pituitary Hormonal Deficiencies in Patients with Pituitary Tumors

2.50
Hdl Handle:
http://hdl.handle.net/10755/304498
Category:
Full-text
Type:
Presentation
Title:
Correlation of Patient Perception of Fatigue, Sleep Disturbance with Motivation and Pituitary Hormonal Deficiencies in Patients with Pituitary Tumors
Author(s):
Yedinak, Christine G.
Lead Author STTI Affiliation:
Non-member
Author Details:
Christine G. Yedinak, DNP, FNP, MN, BS, yedinakc@ohsu.edu
Abstract:

Session presented on: Friday, July 26, 2013

Background: Pituitary tumors may be present in 15-30% of the population and are classified by size ( <1cm or >1cm) and hormonal secretory activity (deficiency or excess).' Sleep disturbance has been demonstrated in patients with large tumors but there is a paucity of information regarding sleep disturbance for small tumors. ''Such tumors have been presumed to be asymptomatic and treatment has been limited to replacement of pituitary hormonal deficiencies or hypersecretion.' Clinically, patients report sleep disturbance, fatigue and motivational deficits. There are no data that correlate these symptoms and no longitudinal data that reflect the impact of biochemical replacement therapies on these dysfunctions.'

Purpose: ' To determine patient perception and severity of sleep disturbance and fatigue and if these correlate to perceived motivational disturbance, tumor size and pituitary hormonal dysfunction in patients with pituitary tumors.

Methods: A total of sixty seven subjects ( 47F/20M) with pituitary tumors meeting criteria were asked to complete a 17 item questionnaire identifying and quantifying sleep disturbance, fatigue and motivational deficiencies on a 6 point Likert scale (no dysfunction to severe dysfunction). On average a moderate level of dysfunction was reported in each category. '

Results: All dysfunctions were significantly correlated (p>.000). There was no significant gender difference in the perception of sleep and motivation dysfunction but females perceived more fatigue than males t(64) = 2.49 ( p=0.015). 'A significant correlation was found between sleep disturbance and multiple pituitary hormonal deficiencies (rs=.27, p= 0.027) and greater sleep disturbance correlated with patients with smaller tumors rs=.256, p=0.037.

Conclusion: Patients with small pituitary tumors (<1cm), without pituitary deficiencies, require evaluation and treatment for sleep disturbance with a particular focus on fatigue in women. Further understanding of the etiology of these dysfunctions is needed in order to develop appropriate therapies.

Keywords:
sleep disturbance; fatigue; pituitary tumor
Repository Posting Date:
22-Oct-2013
Date of Publication:
22-Oct-2013 ; 22-Oct-2013
Conference Date:
2013
Conference Name:
24th International Nursing Research Congress
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Prague, Czech Republic
Description:
24th International Nursing Research Congress Theme: Bridge the Gap Between Research and Practice Through Collaboration. Held at the Hilton Prague Hotel.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_GB
dc.language.isoenen
dc.type.categoryFull-texten
dc.typePresentationen
dc.titleCorrelation of Patient Perception of Fatigue, Sleep Disturbance with Motivation and Pituitary Hormonal Deficiencies in Patients with Pituitary Tumorsen
dc.contributor.authorYedinak, Christine G.en
dc.contributor.departmentNon-memberen
dc.author.detailsChristine G. Yedinak, DNP, FNP, MN, BS, yedinakc@ohsu.eduen
dc.identifier.urihttp://hdl.handle.net/10755/304498-
dc.description.abstract<p>Session presented on: Friday, July 26, 2013</p><b>Background:</b> Pituitary tumors may be present in 15-30% of the population and are classified by size ( <1cm or >1cm) and hormonal secretory activity (deficiency or excess).' Sleep disturbance has been demonstrated in patients with large tumors but there is a paucity of information regarding sleep disturbance for small tumors. ''Such tumors have been presumed to be asymptomatic and treatment has been limited to replacement of pituitary hormonal deficiencies or hypersecretion.' Clinically, patients report sleep disturbance, fatigue and motivational deficits. There are no data that correlate these symptoms and no longitudinal data that reflect the impact of biochemical replacement therapies on these dysfunctions.' <p><b><b>Purpose: </b></b>' To determine patient perception and severity of sleep disturbance and fatigue and if these correlate to perceived motivational disturbance, tumor size and pituitary hormonal dysfunction in patients with pituitary tumors. <p><b><b>Methods: </b></b> A total of sixty seven subjects ( 47F/20M) with pituitary tumors meeting criteria were asked to complete a 17 item questionnaire identifying and quantifying sleep disturbance, fatigue and motivational deficiencies on a 6 point Likert scale (no dysfunction to severe dysfunction). On average a moderate level of dysfunction was reported in each category. ' <p><strong><b>Results: </b></strong>All dysfunctions were significantly correlated (<i>p>.</i>000). There was no significant gender difference in the perception of sleep and motivation dysfunction but females perceived more fatigue than males <i>t<sub>(64)</sub> = </i>2.49 ( <i>p=</i>0.015). 'A significant correlation was found between sleep disturbance and multiple pituitary hormonal deficiencies (<i>rs=.</i>27, p= 0.027) and greater sleep disturbance correlated with patients with smaller tumors <i>rs=</i>.256, <i>p=</i>0.037. <p><b><b>Conclusion</b>: </b> Patients with small pituitary tumors (<1cm), without pituitary deficiencies, require evaluation and treatment for sleep disturbance with a particular focus on fatigue in women. Further understanding of the etiology of these dysfunctions is needed in order to develop appropriate therapies.en
dc.subjectsleep disturbanceen
dc.subjectfatigueen
dc.subjectpituitary tumoren
dc.date.available2013-10-22T20:37:19Z-
dc.date.issued2013-10-22-
dc.date.issued2013-10-22en
dc.date.accessioned2013-10-22T20:37:19Z-
dc.conference.date2013en
dc.conference.name24th International Nursing Research Congressen
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen
dc.conference.locationPrague, Czech Republicen
dc.description24th International Nursing Research Congress Theme: Bridge the Gap Between Research and Practice Through Collaboration. Held at the Hilton Prague Hotel.en
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