Six-Minute Walk Distance Predicts Event-Free Survival After Acute Heart Failure Hospitalization

2.50
Hdl Handle:
http://hdl.handle.net/10755/308152
Category:
Abstract
Type:
Presentation
Title:
Six-Minute Walk Distance Predicts Event-Free Survival After Acute Heart Failure Hospitalization
Author(s):
McCabe, Nancy; Higgins, Melinda; Reilly, Carolyn
Lead Author STTI Affiliation:
Non-member
Author Details:
Nancy McCabe, BA, BSN, RN, nmccabe@emory.edu; Melinda Higgins, PhD; Carolyn Reilly, RN, PhD
Abstract:

Poster presented on: Sunday, November 17, 2013, Saturday, November 16, 2013

Background:

Distance walked on six-minute walk tests (6MWD) is known to predict event-free survival in ambulatory populations of heart failure (HF) patients, but its ability to predict event-free survival following acute HF hospitalization is poorly understood.1 The purpose of this study is to determine whether 6MWD prior to discharge from an acute HF hospitalization is predictive of event-free survival.

Methods:

A secondary analysis of 55 persons with NYHA Class II-III HF (mean age 51 years [SD 13], 65% male, 64% African American, 62% length of diagnosis ≥ 5 years, mean LVEF 24.8% [SD 13.6],) from an on-going HF trial was conducted.  Kaplan-Meier and Cox regression analyses were used to determine the relationship between event-free survival (event=transplant or listed, death, LVAD, or HF rehospitalization) and 6WMD prior to hospital discharge.

Results:

During an average follow-up of 130 days [SD 98], 34 events occurred in 25 (45%) persons (death=5, transplant/listed=3, LVAD=2, HF rehospitalization=24).  Event-free survival was 76%, 65%, 56% at 30, 60, and 90 days after HF hospitalization.  Overall mean 6MWD was 886 feet [SD 405].  Persons with an event had lower mean 6MWD (778 feet [SD 412]) than persons without an event (977 feet [SD 384]), but this was not significant (t(53)=1.85, p=.07). Time to first event was significantly related to 6MWD (χ2 4.59, p=0.03), which remained significant after adjusting for LVEF, race, length of diagnosis, and the Enhanced Feedback for Effective Cardiac Treatment Score, a commonly employed HF mortality risk score and calculated using age, laboratory values, vital signs, and comorbidities (χ2 7.39, p=.02).

Conclusions:

6MWD is a simple, feasible assessment that is independently predictive of event-free survival following acute HF hospitalization.  Further study is warranted regarding the use of the 6MWD to predict adverse events, guide treatment decisions, and discharge planning including timing of discharge in persons with HF.

Keywords:
TYPE NEW KEYWORD HERE; Six-Minute Walk Test; Heart Failure
Repository Posting Date:
19-Dec-2013
Date of Publication:
19-Dec-2013
Conference Date:
2013
Conference Name:
42nd Biennial Convention
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Indianapolis, Indiana, USA
Description:
42nd Biennial Convention 2013 Theme: Give Back to Move Forward. Held at the JW Marriott
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_GB
dc.type.categoryAbstracten_GB
dc.typePresentationen_GB
dc.titleSix-Minute Walk Distance Predicts Event-Free Survival After Acute Heart Failure Hospitalizationen_GB
dc.contributor.authorMcCabe, Nancyen_GB
dc.contributor.authorHiggins, Melindaen_GB
dc.contributor.authorReilly, Carolynen_GB
dc.contributor.departmentNon-memberen_GB
dc.author.detailsNancy McCabe, BA, BSN, RN, nmccabe@emory.edu; Melinda Higgins, PhD; Carolyn Reilly, RN, PhDen_GB
dc.identifier.urihttp://hdl.handle.net/10755/308152-
dc.description.abstract<p>Poster presented on: Sunday, November 17, 2013, Saturday, November 16, 2013</p><p>Background: <p>Distance walked on six-minute walk tests (6MWD) is known to predict event-free survival in ambulatory populations of heart failure (HF) patients, but its ability to predict event-free survival following acute HF hospitalization is poorly understood.<sup>1</sup> The purpose of this study is to determine whether 6MWD prior to discharge from an acute HF hospitalization is predictive of event-free survival. <p>Methods: <p>A secondary analysis of 55 persons with NYHA Class II-III HF (mean age 51 years [SD 13], 65% male, 64% African American, 62% length of diagnosis ≥ 5 years, mean LVEF 24.8% [SD 13.6],) from an on-going HF trial was conducted.  Kaplan-Meier and Cox regression analyses were used to determine the relationship between event-free survival (event=transplant or listed, death, LVAD, or HF rehospitalization) and 6WMD prior to hospital discharge. <p>Results: <p>During an average follow-up of 130 days [SD 98], 34 events occurred in 25 (45%) persons (death=5, transplant/listed=3, LVAD=2, HF rehospitalization=24).  Event-free survival was 76%, 65%, 56% at 30, 60, and 90 days after HF hospitalization.  Overall mean 6MWD was 886 feet [SD 405].  Persons with an event had lower mean 6MWD (778 feet [SD 412]) than persons without an event (977 feet [SD 384]), but this was not significant (<i>t</i>(53)=1.85, p=.07). Time to first event was significantly related to 6MWD (χ<sup>2</sup> 4.59, p=0.03), which remained significant after adjusting for LVEF, race, length of diagnosis, and the Enhanced Feedback for Effective Cardiac Treatment Score, a commonly employed HF mortality risk score and calculated using age, laboratory values, vital signs, and comorbidities (χ<sup>2</sup> 7.39, p=.02). <p>Conclusions: <p>6MWD is a simple, feasible assessment that is independently predictive of event-free survival following acute HF hospitalization.  Further study is warranted regarding the use of the 6MWD to predict adverse events, guide treatment decisions, and discharge planning including timing of discharge in persons with HF. <p>en_GB
dc.subjectTYPE NEW KEYWORD HEREen_GB
dc.subjectSix-Minute Walk Testen_GB
dc.subjectHeart Failureen_GB
dc.date.available2013-12-19T17:27:34Z-
dc.date.issued2013-12-19-
dc.date.accessioned2013-12-19T17:27:34Z-
dc.conference.date2013en_GB
dc.conference.name42nd Biennial Conventionen_GB
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen_GB
dc.conference.locationIndianapolis, Indiana, USAen_GB
dc.description42nd Biennial Convention 2013 Theme: Give Back to Move Forward. Held at the JW Marriotten_GB
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission.en_GB
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