The Impact of Hyperglycemia on Clinical Outcomes of Hospitalized Leukemia Patients

2.50
Hdl Handle:
http://hdl.handle.net/10755/308304
Category:
Abstract
Type:
Presentation
Title:
The Impact of Hyperglycemia on Clinical Outcomes of Hospitalized Leukemia Patients
Author(s):
Storey, Susan L.; Von Ah, Diane
Lead Author STTI Affiliation:
N/A
Author Details:
Susan L. Storey, PhD(c), RN, AOCNS, slstorey@stvincent.org; Diane Von Ah, PhD, RN
Abstract:

Poster presented on: Sunday, November 17, 2013, Saturday, November 16, 2013

The Impact of Hyperglycemia on Clinical Outcomes of Hospitalized Leukemia Patients

 

BACKGROUND

Hyperglycemia in hospitalized patients is a concern for individuals with and without diabetes. The link between hyperglycemia and poor clinical outcomes has been well documented in the critically ill patient population. However, to date, few studies have examined the role hyperglycemia in hospitalized leukemia patient.

 

PURPOSE

The purpose of this study was to compare clinical outcomes in hospitalized leukemia patients with hyperglycemia to those with normoglycemia.

 

THEORETICAL/SCIENTIFIC FRAMEWORK

The Malglycemia Orbit Model was used to guide this study.

 

METHODS

A cohort of 42 consecutive leukemia patients admitted for chemotherapy or symptom management between October, 2009, and February, 2011 were reviewed retrospectively. Fasting blood glucose levels were used and hyperglycemia was defined as a blood glucose ≥ 126 mg/dL. Primary outcomes included length of stay, number of neutropenic days and documented infection. Descriptive statistics and t-tests were used to analyze the data. 

 

RESULTS

For the entire sample, 25 of the 42 (60%) leukemia patients were identified as hyperglycemic; 19 of 42 (45%) had a documented infection and the average hospital length of stay for was 13.8 (SD=14.1) days. Leukemia patients with hyperglycemia had significantly longer length of stay (19.6 days versus 5.2 days; p=0.02) and more neutropenic days (11 days versus .4 days; p<0.000) than patients with normoglycemia. There was no difference in diagnosis of infection between the two groups.

 

CONCLUSIONS                

Hyperglycemia was found to be prevalent in this sample of hospitalized leukemia patients. Leukemia patients with hyperglycemia had poorer outcomes including longer length of stay in the hospital and more neutropenic days. These findings suggest that managing blood glucose levels to avoid hyperglycemia could improve outcomes for leukemia patients. More research in this is needed to better understand the impact hyperglycemia has on outcomes of hospitalized leukemia patients.

Keywords:
Hyperglycemia; Clinical outcomes; Acute Myeloid Leukemia
Repository Posting Date:
19-Dec-2013
Date of Publication:
19-Dec-2013
Conference Date:
2013
Conference Name:
42nd Biennial Convention
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Indianapolis, Indiana, USA
Description:
42nd Biennial Convention 2013 Theme: Give Back to Move Forward. Held at the JW Marriott
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_GB
dc.type.categoryAbstracten_GB
dc.typePresentationen_GB
dc.titleThe Impact of Hyperglycemia on Clinical Outcomes of Hospitalized Leukemia Patientsen_GB
dc.contributor.authorStorey, Susan L.en_GB
dc.contributor.authorVon Ah, Dianeen_GB
dc.contributor.departmentN/Aen_GB
dc.author.detailsSusan L. Storey, PhD(c), RN, AOCNS, slstorey@stvincent.org; Diane Von Ah, PhD, RNen_GB
dc.identifier.urihttp://hdl.handle.net/10755/308304-
dc.description.abstract<p>Poster presented on: Sunday, November 17, 2013, Saturday, November 16, 2013</p><b>The Impact of Hyperglycemia on Clinical Outcomes of Hospitalized Leukemia Patients</b><b></b><p><b> </b><p><b>BACKGROUND </b><p>Hyperglycemia in hospitalized patients is a concern for individuals with and without diabetes. The link between hyperglycemia and poor clinical outcomes has been well documented in the critically ill patient population. However, to date, few studies have examined the role hyperglycemia in hospitalized leukemia patient. <p><b> </b><p><b>PURPOSE</b><p>The purpose of this study was to compare clinical outcomes in hospitalized leukemia patients with hyperglycemia to those with normoglycemia<b>. </b><p><b> </b><p><b>THEORETICAL/SCIENTIFIC FRAMEWORK </b><p>The Malglycemia Orbit Model was used to guide this study. <p><b> </b><p><b>METHODS </b><p>A cohort of 42 consecutive leukemia patients admitted for chemotherapy or symptom management between October, 2009, and February, 2011 were reviewed retrospectively. Fasting blood glucose levels were used and hyperglycemia was defined as a blood glucose ≥ 126 mg/dL. Primary outcomes included length of stay, number of neutropenic days and documented infection. Descriptive statistics and t-tests were used to analyze the data.  <p><b> </b><p><b>RESULTS</b><p>For the entire sample, 25 of the 42 (60%) leukemia patients were identified as hyperglycemic; 19 of 42 (45%) had a documented infection and the average hospital length of stay for was 13.8 (SD=14.1) days. Leukemia patients with hyperglycemia had significantly longer length of stay (19.6 days versus 5.2 days; <i>p=</i>0.02) and more neutropenic days (11 days versus .4 days; p<0.000) than patients with normoglycemia. There was no difference in diagnosis of infection between the two groups. <p><b> </b><p><b>CONCLUSIONS                 </b><p>Hyperglycemia was found to be prevalent in this sample of hospitalized leukemia patients. Leukemia patients with hyperglycemia had poorer outcomes including longer length of stay in the hospital and more neutropenic days. These findings suggest that managing blood glucose levels to avoid hyperglycemia could improve outcomes for leukemia patients. More research in this is needed to better understand the impact hyperglycemia has on outcomes of hospitalized leukemia patients.en_GB
dc.subjectHyperglycemiaen_GB
dc.subjectClinical outcomesen_GB
dc.subjectAcute Myeloid Leukemiaen_GB
dc.date.available2013-12-19T17:29:34Z-
dc.date.issued2013-12-19-
dc.date.accessioned2013-12-19T17:29:34Z-
dc.conference.date2013en_GB
dc.conference.name42nd Biennial Conventionen_GB
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen_GB
dc.conference.locationIndianapolis, Indiana, USAen_GB
dc.description42nd Biennial Convention 2013 Theme: Give Back to Move Forward. Held at the JW Marriotten_GB
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission.en_GB
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