Relationships of Toxoplasma Gondii Antibody Titers and Dysphoric Mood in Female Veterans

2.50
Hdl Handle:
http://hdl.handle.net/10755/308310
Category:
Abstract
Type:
Presentation
Title:
Relationships of Toxoplasma Gondii Antibody Titers and Dysphoric Mood in Female Veterans
Author(s):
Duffy, Allyson R
Lead Author STTI Affiliation:
Delta Beta-at-Large
Author Details:
Allyson R Duffy, RN, MSN, aradford@health.usf.edu
Abstract:

Poster presented on: Saturday, November 16, 2013, Sunday, November 17, 2013

A cross-sectional study of ethnically diverse female veterans (n=53) was conducted.  These veterans had a mean age of 49.8 years.  A demographic scale and a panel of psychosocial instruments were employed. Blood was drawn for inflammatory markers and T. gondii titers.  Chronic T. gondii infection has been associated with behavioral and mood changes in several populations, but has not been studied in veterans.

Sixteen percent of this sample screened positive for PTSD and 20% for depression.  T. gondii chronic infection, defined as a titer of 10 IU/ml or higher was present in 16% of the sample, and 5% of the sample had levels consistent with reactivation of this brain parasite (>200 IU/ml). The titers associated with chronic infection were correlated significantly with depression (p<.03), anger (p<.001) and total disturbance (p<.03). Women screening positive for depression and/or PTSD had 4 times higher titers than non-depressed women. In addition, T. gondii positive women reported significantly more experiences of military sexual trauma (p<.04).

These data provide a snapshot of a group of older women veterans with a 22% infection T. gondii infection rate. These women may have been exposed in the middle east where the infection rate is much higher than in the U.S. This parasite localizes in the brain and may influence risk taking, reaction time, depression, schizophrenia and suicidality risk.  The role of this organism in military related psychological and neurological sequelae deserves attention.

Keywords:
TYPE NEW KEYWORD HERE; Toxoplasma gondii; dysphoric mood
Repository Posting Date:
19-Dec-2013
Date of Publication:
19-Dec-2013
Conference Date:
2013
Conference Name:
42nd Biennial Convention
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Indianapolis, Indiana, USA
Description:
42nd Biennial Convention 2013 Theme: Give Back to Move Forward. Held at the JW Marriott
Note:
This is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission.

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_GB
dc.type.categoryAbstracten_GB
dc.typePresentationen_GB
dc.titleRelationships of Toxoplasma Gondii Antibody Titers and Dysphoric Mood in Female Veteransen_GB
dc.contributor.authorDuffy, Allyson Ren_GB
dc.contributor.departmentDelta Beta-at-Largeen_GB
dc.author.detailsAllyson R Duffy, RN, MSN, aradford@health.usf.eduen_GB
dc.identifier.urihttp://hdl.handle.net/10755/308310-
dc.description.abstract<p>Poster presented on: Saturday, November 16, 2013, Sunday, November 17, 2013</p>A cross-sectional study of ethnically diverse female veterans (n=53) was conducted.  These veterans had a mean age of 49.8 years.  A demographic scale and a panel of psychosocial instruments were employed. Blood was drawn for inflammatory markers and <i>T. gondii</i> titers.  Chronic <i>T. gondii</i> infection has been associated with behavioral and mood changes in several populations, but has not been studied in veterans. <p>Sixteen percent of this sample screened positive for PTSD and 20% for depression.  <i>T. gondii</i> chronic infection, defined as a titer of 10 IU/ml or higher was present in 16% of the sample, and 5% of the sample had levels consistent with reactivation of this brain parasite (>200 IU/ml). The titers associated with chronic infection were correlated significantly with depression (p<.03), anger (p<.001) and total disturbance (p<.03). Women screening positive for depression and/or PTSD had 4 times higher titers than non-depressed women. In addition, <i>T. gondii</i> positive women reported significantly more experiences of military sexual trauma (p<.04). <p>These data provide a snapshot of a group of older women veterans with a 22% infection <i>T. gondii</i> infection rate. These women may have been exposed in the middle east where the infection rate is much higher than in the U.S. This parasite localizes in the brain and may influence risk taking, reaction time, depression, schizophrenia and suicidality risk.  The role of this organism in military related psychological and neurological sequelae deserves attention.en_GB
dc.subjectTYPE NEW KEYWORD HEREen_GB
dc.subjectToxoplasma gondiien_GB
dc.subjectdysphoric mooden_GB
dc.date.available2013-12-19T17:29:39Z-
dc.date.issued2013-12-19-
dc.date.accessioned2013-12-19T17:29:39Z-
dc.conference.date2013en_GB
dc.conference.name42nd Biennial Conventionen_GB
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen_GB
dc.conference.locationIndianapolis, Indiana, USAen_GB
dc.description42nd Biennial Convention 2013 Theme: Give Back to Move Forward. Held at the JW Marriotten_GB
dc.description.noteThis is an abstract-only submission. If the author has submitted a full-text item based on this abstract, you may find it by browsing the Virginia Henderson Global Nursing e-Repository by author. If author contact information is available in this abstract, please feel free to contact him or her with your queries regarding this submission.en_GB
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