A RCT of the Effects of Medication Adherence Therapy for People with Schizophrenia Specturm Disorders

2.50
Hdl Handle:
http://hdl.handle.net/10755/335032
Category:
Full-text
Type:
Presentation
Title:
A RCT of the Effects of Medication Adherence Therapy for People with Schizophrenia Specturm Disorders
Other Titles:
Global Nursing Research: Medication Related Randomized Controlled Trials
Author(s):
Chien, Wai Tong; Mui, Jolene; Cheung, Eric
Lead Author STTI Affiliation:
Non-member
Author Details:
Wai Tong Chien, PhD, MPhil, BN, RMN, wai.tong.chien@polyu.edu.hk; Jolene Mui, MSc, BSc, RMN (UK, HK), CPN (HK); Eric Cheung, MB, BS (HK), FRCPsych (UK), FHKCPsych, FHKAM (Psychiatry)
Abstract:
Session presented on Saturday, July 26, 2014: Purpose: This randomized controlled trial, using a repeated measures control group design, tested the effectiveness of a 6-session medication adherence program for Chinese outpatients with schizophrenia and its subtypes over a 12-month follow-up. Methods: A two-site controlled trial was conducted with 134 Chinese patients with psychotic disorders in Hong Kong. The program is a motivational and insight-inducing educational program that addresses patients' awareness and knowledge of schizophrenia and skills of medication management (Gray et al., 2006) . They were randomly assigned to either the medication adherence program or usual psychiatric outpatient care. The patients' levels of medication adherence (using Drug Attitude Inventory, DAI), mental (Positive and Negative Syndrome Scale, PANSS) and psychosocial (Specific Level of Functioning scale, SLOF) functioning, insights into illness (Insight and Treatment Attitude Questionnaire, ITAQ), and re-hospitalization rates (number and length in six months) were measured at recruitment and at one week (Post-test 1) and 12 months (Post-test 2) after the intervention. Results: Preliminary results of MANOVA test indicated that the participants in the NPP reported significantly overall improvements on the patient outcomes [F (1, 132) = 6.12, p=0.005; Wilks' Lambda= 0.95; a large effect with partial (eta)2 = 0.39]. Post hoc Tukey's HSD test indicated that their mental state (PANSS score), attitude towards medication use (DAI score), and insight into the illness (ITAQ scores) were significantly improved and hospitalization rates (both number and length of re-admissions) were significantly reduced at both one week and 12 months after the intervention, compared with standard care. Conclusion: The results of this controlled trial can provide evidence of the effectiveness of a community-based adherence therapy for schizophrenia in improving medication adherence, mental condition and insight into the illness and its treatment. This can then result in reducing the risk of relapse and re-admission over 12 months, and hence minimize those tragic events in relation to relapse such as violence and self-harm, as well as the medical and social costs.
Keywords:
motivational technique; medication adherence; randomised controlled trial
Repository Posting Date:
17-Nov-2014
Date of Publication:
17-Nov-2014 ; 17-Nov-2014
Other Identifiers:
INRC14G10
Conference Date:
2014
Conference Name:
25th International Nursing Research Congress
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Hong Kong
Description:
International Nursing Research Congress, 2014 Theme: Engaging Colleagues: Improving Global Health Outcomes. Held at the Hong Kong Convention and Exhibition Centre, Wanchai, Hong Kong

Full metadata record

DC FieldValue Language
dc.language.isoen_USen_GB
dc.language.isoenen
dc.type.categoryFull-texten
dc.typePresentationen
dc.titleA RCT of the Effects of Medication Adherence Therapy for People with Schizophrenia Specturm Disordersen
dc.title.alternativeGlobal Nursing Research: Medication Related Randomized Controlled Trialsen
dc.contributor.authorChien, Wai Tongen
dc.contributor.authorMui, Joleneen
dc.contributor.authorCheung, Ericen
dc.contributor.departmentNon-memberen
dc.author.detailsWai Tong Chien, PhD, MPhil, BN, RMN, wai.tong.chien@polyu.edu.hk; Jolene Mui, MSc, BSc, RMN (UK, HK), CPN (HK); Eric Cheung, MB, BS (HK), FRCPsych (UK), FHKCPsych, FHKAM (Psychiatry)en
dc.identifier.urihttp://hdl.handle.net/10755/335032-
dc.description.abstractSession presented on Saturday, July 26, 2014: Purpose: This randomized controlled trial, using a repeated measures control group design, tested the effectiveness of a 6-session medication adherence program for Chinese outpatients with schizophrenia and its subtypes over a 12-month follow-up. Methods: A two-site controlled trial was conducted with 134 Chinese patients with psychotic disorders in Hong Kong. The program is a motivational and insight-inducing educational program that addresses patients' awareness and knowledge of schizophrenia and skills of medication management (Gray et al., 2006) . They were randomly assigned to either the medication adherence program or usual psychiatric outpatient care. The patients' levels of medication adherence (using Drug Attitude Inventory, DAI), mental (Positive and Negative Syndrome Scale, PANSS) and psychosocial (Specific Level of Functioning scale, SLOF) functioning, insights into illness (Insight and Treatment Attitude Questionnaire, ITAQ), and re-hospitalization rates (number and length in six months) were measured at recruitment and at one week (Post-test 1) and 12 months (Post-test 2) after the intervention. Results: Preliminary results of MANOVA test indicated that the participants in the NPP reported significantly overall improvements on the patient outcomes [F (1, 132) = 6.12, p=0.005; Wilks' Lambda= 0.95; a large effect with partial (eta)2 = 0.39]. Post hoc Tukey's HSD test indicated that their mental state (PANSS score), attitude towards medication use (DAI score), and insight into the illness (ITAQ scores) were significantly improved and hospitalization rates (both number and length of re-admissions) were significantly reduced at both one week and 12 months after the intervention, compared with standard care. Conclusion: The results of this controlled trial can provide evidence of the effectiveness of a community-based adherence therapy for schizophrenia in improving medication adherence, mental condition and insight into the illness and its treatment. This can then result in reducing the risk of relapse and re-admission over 12 months, and hence minimize those tragic events in relation to relapse such as violence and self-harm, as well as the medical and social costs.en
dc.subjectmotivational techniqueen
dc.subjectmedication adherenceen
dc.subjectrandomised controlled trialen
dc.date.available2014-11-17T13:42:26Z-
dc.date.issued2014-11-17-
dc.date.issued2014-11-17en
dc.date.accessioned2014-11-17T13:42:26Z-
dc.conference.date2014en
dc.conference.name25th International Nursing Research Congressen
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen
dc.conference.locationHong Kongen
dc.descriptionInternational Nursing Research Congress, 2014 Theme: Engaging Colleagues: Improving Global Health Outcomes. Held at the Hong Kong Convention and Exhibition Centre, Wanchai, Hong Kongen
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