Exploring Symptom Clusters in Individuals Undergoing Surgery for Pancreatic Cancer

2.50
Hdl Handle:
http://hdl.handle.net/10755/601746
Category:
Full-text
Format:
Text-based Document
Type:
Presentation
Title:
Exploring Symptom Clusters in Individuals Undergoing Surgery for Pancreatic Cancer
Other Titles:
Promoting Clinical Outcomes in Cancer Patients [Session]
Author(s):
Burrell, Sherry A.; Smeltzer, Suzanne C.; Yeo, Theresa Pluth
Lead Author STTI Affiliation:
Xi
Author Details:
Sherry A. Burrell, RN, ACNS-BC, CNE, sherryb@camden.rutgers.edu; Suzanne C. Smeltzer, RN, FAAN; Theresa Pluth Yeo, RN, AOCNP
Abstract:
Session presented on Monday, July 27, 2015: Purpose: 'The aims of this primary nested, longitudinal, exploratory study were to explore self-reported symptom profiles to identify the presence of and changes in symptom clusters (SCs) and factors that influence the severity of the SCs in individuals with stage II pancreatic cancer (PC) before and at three, six, and nine months after'surgery alone or in combination with adjuvant chemotherapy or chemoradiation therapy. '' Methods: 'This primary nested, longitudinal, exploratory study'was conducted within an ongoing single center, prospective, randomized, double-blind, placebo-controlled clinical trial of ethanol celiac plexis neurolysis versus placebo for pain control (the parent study).' One hundred and forty-three patients undergoing surgical resection for stage II PC were identified through the parent study located at a comprehensive cancer center in the northeastern United States. 'The Theory of Unpleasant Symptoms served as the theoretical framework to guide this study. 'Study variables included: 17 PC symptoms; 14 physiological factors; 4 psychological factors; and 6 situational factors.' Symptom data were measured by the Functional Assessment in Cancer Therapy: Hepatobiliary Cancer Tool.' Demographic and clinical data were obtained from a review of parent study folders that included supportive documentation from patients' electronic health records.' Major statistical methods used included exploratory and confirmatory factor analyses and generalized linear modeling.' Results: The prevalence and severity of symptoms varied over time; however,'five symptoms (fatigue, trouble sleeping, poor appetite, weight loss, and trouble digesting food) were consistently among the most prevalent and severe symptoms.'Sixteen'SCs were identified that'were not identical over time; although, four core'SC'sub-groupings were found, which included: a) depression and anxiety; b) trouble digesting food and loss of bowel control; c) change in taste, dry mouth, fatigue, and weight loss; and d) nausea, back pain, and abdominal pain / cramping.' Pre-operative factors that influenced the severity of'a SCs were also identified.'Pain status was'associated with the pain-gastrointestinal SC (slope=0.71; 95% CI 0.31, 1.11; p=0.0364) and cancer worry'was associated with the mood'SC'(slope=0.34, 95% CI 0.20, 0.48; p=0.0006). Conclusion: This was the first study to examine symptoms to identify and follow'SCs over time in post-operative patients with stage II PC.'Findings provided evidence of the existence of 16 distinict SCs, 4 symptom cluster core sub-groupings, and'2 pre-operative'factors that influenced the severity of'SCs in PC patients within the first 9 months of surgery.'The findings from this study may be used to provide anticipatory guidance and inform prevention, assessment, and management of'SCs in PC surgical populations.
Keywords:
Pancreatic Cancer; Surgery; Symptom Clusters
Repository Posting Date:
17-Mar-2016
Date of Publication:
17-Mar-2016 ; 17-Mar-2016
Other Identifiers:
INRC15L04
Conference Date:
2015
Conference Name:
26th International Nursing Research Congress
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
San Juan, Puerto Rico
Description:
Research Congress 2015 Theme: Question Locally, Engage Regionally, Apply Globally. Held at the Puerto Rico Convention Center.

Full metadata record

DC FieldValue Language
dc.language.isoenen
dc.type.categoryFull-texten
dc.formatText-based Documenten
dc.typePresentationen
dc.titleExploring Symptom Clusters in Individuals Undergoing Surgery for Pancreatic Canceren
dc.title.alternativePromoting Clinical Outcomes in Cancer Patients [Session]en
dc.contributor.authorBurrell, Sherry A.en
dc.contributor.authorSmeltzer, Suzanne C.en
dc.contributor.authorYeo, Theresa Pluthen
dc.contributor.departmentXien
dc.author.detailsSherry A. Burrell, RN, ACNS-BC, CNE, sherryb@camden.rutgers.edu; Suzanne C. Smeltzer, RN, FAAN; Theresa Pluth Yeo, RN, AOCNPen
dc.identifier.urihttp://hdl.handle.net/10755/601746-
dc.description.abstractSession presented on Monday, July 27, 2015: Purpose: 'The aims of this primary nested, longitudinal, exploratory study were to explore self-reported symptom profiles to identify the presence of and changes in symptom clusters (SCs) and factors that influence the severity of the SCs in individuals with stage II pancreatic cancer (PC) before and at three, six, and nine months after'surgery alone or in combination with adjuvant chemotherapy or chemoradiation therapy. '' Methods: 'This primary nested, longitudinal, exploratory study'was conducted within an ongoing single center, prospective, randomized, double-blind, placebo-controlled clinical trial of ethanol celiac plexis neurolysis versus placebo for pain control (the parent study).' One hundred and forty-three patients undergoing surgical resection for stage II PC were identified through the parent study located at a comprehensive cancer center in the northeastern United States. 'The Theory of Unpleasant Symptoms served as the theoretical framework to guide this study. 'Study variables included: 17 PC symptoms; 14 physiological factors; 4 psychological factors; and 6 situational factors.' Symptom data were measured by the Functional Assessment in Cancer Therapy: Hepatobiliary Cancer Tool.' Demographic and clinical data were obtained from a review of parent study folders that included supportive documentation from patients' electronic health records.' Major statistical methods used included exploratory and confirmatory factor analyses and generalized linear modeling.' Results: The prevalence and severity of symptoms varied over time; however,'five symptoms (fatigue, trouble sleeping, poor appetite, weight loss, and trouble digesting food) were consistently among the most prevalent and severe symptoms.'Sixteen'SCs were identified that'were not identical over time; although, four core'SC'sub-groupings were found, which included: a) depression and anxiety; b) trouble digesting food and loss of bowel control; c) change in taste, dry mouth, fatigue, and weight loss; and d) nausea, back pain, and abdominal pain / cramping.' Pre-operative factors that influenced the severity of'a SCs were also identified.'Pain status was'associated with the pain-gastrointestinal SC (slope=0.71; 95% CI 0.31, 1.11; p=0.0364) and cancer worry'was associated with the mood'SC'(slope=0.34, 95% CI 0.20, 0.48; p=0.0006). Conclusion: This was the first study to examine symptoms to identify and follow'SCs over time in post-operative patients with stage II PC.'Findings provided evidence of the existence of 16 distinict SCs, 4 symptom cluster core sub-groupings, and'2 pre-operative'factors that influenced the severity of'SCs in PC patients within the first 9 months of surgery.'The findings from this study may be used to provide anticipatory guidance and inform prevention, assessment, and management of'SCs in PC surgical populations.en
dc.subjectPancreatic Canceren
dc.subjectSurgeryen
dc.subjectSymptom Clustersen
dc.date.available2016-03-17T12:54:27Zen
dc.date.issued2016-03-17-
dc.date.issued2016-03-17en
dc.date.accessioned2016-03-17T12:54:27Zen
dc.conference.date2015en
dc.conference.name26th International Nursing Research Congressen
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen
dc.conference.locationSan Juan, Puerto Ricoen
dc.descriptionResearch Congress 2015 Theme: Question Locally, Engage Regionally, Apply Globally. Held at the Puerto Rico Convention Center.en
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