Sleep Disturbance and Fatigue in Renal Transplant Patients: A Pilot Study

2.50
Hdl Handle:
http://hdl.handle.net/10755/603085
Category:
Full-text
Format:
Text-based Document
Type:
Presentation
Title:
Sleep Disturbance and Fatigue in Renal Transplant Patients: A Pilot Study
Other Titles:
Research and Improvements in Clinical Care [Session]
Author(s):
Landreneau, Kandace
Lead Author STTI Affiliation:
Beta Chi
Author Details:
Kandace Landreneau, CCTC, landreneauk@nsula.edu
Abstract:
Session presented on Monday, November 9, 2015: Background :  Renal disease is the ninth leading cause of death in the United States. An estimated 80,000 are diagnosed annually with chronic renal failure, and over 400,000 Americans are receiving renal replacement therapy, dialysis or renal transplantation, to sustain life.  When a patient receives a renal transplant (RT), and no longer has renal failure, it has been assumed that any prior sleep problems are resolved.  These patients had experienced uremia with symptoms that include fatigue and day/night reversal. Day/night reversal or circadian rhythm disturbances and sleep problems have been recognized as an important issue in dialysis patients. However, the extent to which sleep problems continue after RT remains unclear. Purpose :  The purpose of this pilot study was to categorize types of sleep problems in patients who have experienced renal transplantation, test recruitment procedures for a larger study, determine feasibility of questionnaires and actigraphy monitors, and gather preliminary data regarding valid and reliable measures for sleep disturbance and fatigue. Design and Methods:   A pilot study was conducted with the screening of 10 participants from a renal transplant clinic in a western U.S. state. Four participants met the criteria for a sleep disturbance and continued the study. In addition to actigraphy monitoring as a measure of sleep, biomarkers included hemoglobin for anemia and hemoglobin A1C as an indicator of glucose metabolism related to fatigue level along with relevant personal and treatment variables.  Results: Four of the 10 participants had sleep disturbance and continued in the study. Even though there were only 4 participants, self-report of sleep quality correlated with actigraphy in all 4 participants.  The better the self-report, the better the sleep efficiency and the more minutes of sleep.  The lab values (Creatinine/BUN/Hgb/Hct) and the sleep variables (fatigue, sleep quality, sleep efficiency) revealed that the better the sleep and the more minutes of sleep, the lower the creatinine and BUN.  Conclusions: The pilot study aims were achieved and the plan to do a larger study is appropriate.  Sleep disturbance and fatigue has not been fully studied in renal transplant patients and further study is needed - in this population - for best and appropriate interventions.
Keywords:
renal transplant; sleep disturbance; fatigue
Repository Posting Date:
21-Mar-2016
Date of Publication:
21-Mar-2016
Other Identifiers:
CONV15F16
Conference Date:
2015
Conference Name:
43rd Biennial Convention
Conference Host:
Sigma Theta Tau International, the Honor Society of Nursing
Conference Location:
Las Vegas, Nevada, USA
Description:
43rd Biennial Convention 2015 Theme: Serve Locally, Transform Regionally, Lead Globally.`

Full metadata record

DC FieldValue Language
dc.language.isoen_USen
dc.type.categoryFull-texten
dc.formatText-based Documenten
dc.typePresentationen
dc.titleSleep Disturbance and Fatigue in Renal Transplant Patients: A Pilot Studyen
dc.title.alternativeResearch and Improvements in Clinical Care [Session]en
dc.contributor.authorLandreneau, Kandaceen
dc.contributor.departmentBeta Chien
dc.author.detailsKandace Landreneau, CCTC, landreneauk@nsula.eduen
dc.identifier.urihttp://hdl.handle.net/10755/603085en
dc.description.abstractSession presented on Monday, November 9, 2015: Background :  Renal disease is the ninth leading cause of death in the United States. An estimated 80,000 are diagnosed annually with chronic renal failure, and over 400,000 Americans are receiving renal replacement therapy, dialysis or renal transplantation, to sustain life.  When a patient receives a renal transplant (RT), and no longer has renal failure, it has been assumed that any prior sleep problems are resolved.  These patients had experienced uremia with symptoms that include fatigue and day/night reversal. Day/night reversal or circadian rhythm disturbances and sleep problems have been recognized as an important issue in dialysis patients. However, the extent to which sleep problems continue after RT remains unclear. Purpose :  The purpose of this pilot study was to categorize types of sleep problems in patients who have experienced renal transplantation, test recruitment procedures for a larger study, determine feasibility of questionnaires and actigraphy monitors, and gather preliminary data regarding valid and reliable measures for sleep disturbance and fatigue. Design and Methods:   A pilot study was conducted with the screening of 10 participants from a renal transplant clinic in a western U.S. state. Four participants met the criteria for a sleep disturbance and continued the study. In addition to actigraphy monitoring as a measure of sleep, biomarkers included hemoglobin for anemia and hemoglobin A1C as an indicator of glucose metabolism related to fatigue level along with relevant personal and treatment variables.  Results: Four of the 10 participants had sleep disturbance and continued in the study. Even though there were only 4 participants, self-report of sleep quality correlated with actigraphy in all 4 participants.  The better the self-report, the better the sleep efficiency and the more minutes of sleep.  The lab values (Creatinine/BUN/Hgb/Hct) and the sleep variables (fatigue, sleep quality, sleep efficiency) revealed that the better the sleep and the more minutes of sleep, the lower the creatinine and BUN.  Conclusions: The pilot study aims were achieved and the plan to do a larger study is appropriate.  Sleep disturbance and fatigue has not been fully studied in renal transplant patients and further study is needed - in this population - for best and appropriate interventions.en
dc.subjectrenal transplanten
dc.subjectsleep disturbanceen
dc.subjectfatigueen
dc.date.available2016-03-21T16:42:59Zen
dc.date.issued2016-03-21en
dc.date.accessioned2016-03-21T16:42:59Zen
dc.conference.date2015en
dc.conference.name43rd Biennial Conventionen
dc.conference.hostSigma Theta Tau International, the Honor Society of Nursingen
dc.conference.locationLas Vegas, Nevada, USAen
dc.description43rd Biennial Convention 2015 Theme: Serve Locally, Transform Regionally, Lead Globally.`en
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